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adenosine adenosine receptors and the regulation of glial cells in neuronal damage

Báo cáo khoa học: MicroRNAs and the regulation of fibrosis potx

Báo cáo khoa học: MicroRNAs and the regulation of fibrosis potx

Báo cáo khoa học

... deposition of collagen and other ECM proteins within the pulmonary interstitium and is commonly associated with the up -regulation of TGF-b [31] Little is known regarding the role of miRNAs in lung ... Irregularities in multiple pathways involved in tissue repair and in ammation can lead to the development of fibrosis Collagens are the predominant ECM proteins, while other ECM proteins such as fibronectins, ... understood and there are few effective therapies For these reasons, and knowing the multitude of pathways that miRNAs can affect, it is envisaged that investigating the roles of miRNAs in fibrosis...
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Báo cáo khoa học: Galanin-like peptide and the regulation of feeding behavior and energy metabolism pptx

Báo cáo khoa học: Galanin-like peptide and the regulation of feeding behavior and energy metabolism pptx

Báo cáo khoa học

... neurons in the LH and tyrosine hydroxylase-containing neurons in the ARC, although their physiological actions are uncertain GALP neurons in the ARC are innervated by orexin neurons in the LH and ... through thermogenesis by long-term activation of the sympathetic nervous system Therefore, both prostaglandins in the brain and uncoupling protein-1 in peripheral tissue are involved in GALP-induced ... one in which GALPcontaining neurons project from the ARC to the PVN, and the other in which they project to the MPA, bed nucleus of the stria terminalis and lateral septal nucleus Central administration...
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báo cáo khoa học:

báo cáo khoa học: " Trust and the regulation of pharmaceuticals: South Asia in a globalised world" ppt

Báo cáo khoa học

... than writing generic names, with the rationale that in the market place, and with increasing numbers of brands coming and going, this was the best way to be sure of the quality of the drugs In one ... the chain The president of the Association of Pharmaceutical Producers of Nepal linked the gift and bonus giving to the increase in competition in the market But he defined the problem with the ... mutatis mutandis, in India and in Nepal But here, as in some other parts of the world, physicians face additional complications in sustaining the trust of their patients, because there are state-sanctioned...
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Báo cáo y học:

Báo cáo y học: "Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor" ppsx

Báo cáo khoa học

... effect of HLA in RA in the Spanish population, we investigated the association of SE-containing HLA-DRB1 alleles with susceptibility to RA and then examined the possible protective effect of HLA-DR3 ... participated in data collection and helped draft the manuscript GO helped in the statistical analysis and participated in the design of the study MAL-N and JLV carried out the HLA determination, ... no competing interests Authors' contributions AB, AC, JM, EM-M and DP-S participated in the design of the study, helped in the statistical analysis, and helped draft the manuscript TC and EM-C...
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Báo cáo y học:

Báo cáo y học: "Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology" ppsx

Báo cáo khoa học

... (blocked arrows) of different stages in the proposed pathway are indicated Genistein is an inhibitor of tyrosine protein kinase and competitive inhibitor of ATP in other protein kinase reactions; ... switches off the induction of Bcl-2 and rather predominates Bax in controlling apoptosis within the perinatal lung This reinforces the presumption that signaling pathways mediating apoptosis in response ... online http://respiratory-research.com/content/3/1/26 a decrease in the thickness of the interstitium, thinning of the epithelium and separation of the terminal air units This stage also marks the...
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Báo cáo y học:

Báo cáo y học: "Global nucleosome distribution and the regulation of transcription in yeas" doc

Báo cáo khoa học

... in vivo and then separating the aqueous phase from the organic phase in phenol:chloroform extractions Free DNA segregates into the aqueous phase and DNA bound to proteins remain s in the organic ... results in differential segregation of intergenic regions of the genome into the aqueous phase Nagy et al [13] proposed that this may be a result of different efficiency of chromatin cross-linking ... depleted of nucleosomes, and other proteins bound at these regions may not cross-link to DNA as efficiently as histones In either case, the physical fractionation of yeast chromatin suggests that the...
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UN-REDD programme and the progress of implementing REDD in Vietnam

UN-REDD programme and the progress of implementing REDD in Vietnam

Báo cáo khoa học

... Protection in 2005 and carbon rights as well as the decentralization of power to the Ministry of Agriculture and Rural Development and Ministry of Natural Resources and Environment in the land allocation ... more interested in the financial benefits of REDD rather than the social and environmental benefits Then now, the question is: In your opinion, how to sustain the programme’s efficiency? I think ... and has generated important discussions among forestry policy makers In the pilot province of Lam Dong, the pilot exercises on applying the principles of Free, Prior and Informed Consent in the...
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Tài liệu Corporate Ownership structure and the Informativeness of Accounting Earnings in East Asia doc

Tài liệu Corporate Ownership structure and the Informativeness of Accounting Earnings in East Asia doc

Kế toán - Kiểm toán

... earnings divided by the market value of equity at the beginning of the year SIZE = the natural logarithm of the market value of equity in millions of U.S dollar at the beginning of the year Q = the ... logarithm of the market value of equity in millions of U.S dollars at the beginning of year t; Qit = the market value of equity divided by the book value of total assets at the beginning of year ... that the entrepreneur controls 25% of Firm B the weakest link in the chain of voting rights At the same time, the entrepreneur owns about 8% of the cash flow rights of Firm B, the product of the...
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Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx

Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx

Báo cáo khoa học

... and 3) Translational regulation of iPLA2c in myocardium Owing to the obvious complexity of the regulation of iPLA2c resulting from the combined presence of transcriptional and translational regulation, ... which regulates the flow of the Gibbs free energy inherent in C–C bonds in fatty acids into the production of either chemical energy or heat by directing the flow of iPLA2c into either the peroxisomal ... boundaries of the iPLA2c gene are shown in scale (kb) The 13 exons of the iPLA2c gene are indicated as boxes Spaces between the exons represent the relative sizes of the 12 introns contained within the...
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Multidimensional Poverty and the State of Child Health in India pdf

Multidimensional Poverty and the State of Child Health in India pdf

Sức khỏe trẻ em

... from the composite wealth index using the PCA The cut off point of poor in is 26% in urban areas and 28% in rural areas This cut-off point is equivalent to the poverty estimates of the Planning ... Pradesh and Nagaland had a value of three and more indicating higher inequality in the state of health care All other states had a value between two and three indicating the degree of inequality in ... variable in the construction of the wealth index for rural India Third, we have equated the cutoff point of the poor to the Planning Commission, Government of India estimates of poverty in 14 2004-05,...
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Trial and Error: J. Marion Sims and the Birth of Modern Gynecology in the American South docx

Trial and Error: J. Marion Sims and the Birth of Modern Gynecology in the American South docx

Sức khỏe phụ nữ

... fame were a result of his surgical discoveries, including the invention the Sims Speculum and the Sims Position, and the use of silver sutures to prevent internal infections These innovations eventually ... saying “there is no science in it (and) there is no honor to be achieved in it.”7 This was a popular perception of the field; in the South Carolina piedmont in the 1830s, a career in medicine ... students examining Lucy, while Anarcha and Betsy watch from behind a curtain This artist’s rendering does not show the pain or suffering of these women, and fails to include any sign of their ailments...
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Cost Recovery and the Crisis of Service Delivery in South Africa ppt

Cost Recovery and the Crisis of Service Delivery in South Africa ppt

Khoa học xã hội

... commercial, industrial and high-income areas Consider the following The Durban Chamber of Commerce and Industry “has in recent years expressed the concern of its members regarding the increasing cost of ... bulk of it was indirect, extracted unwittingly from the apartheid state in the form of payment boycotts by township residents in the 1980s and early 1990s In spite of the boycotts, the apartheid ... interests The point of departure for any community-controlled development process is that finance and the financial system must serve the interests of poor communities and not the interests of...
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Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf

Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf

Ngân hàng - Tín dụng

... the left to the right-hand side of the map decreases the probability of Expected-Debt to be equal to ô ằ (increase in indebtedness) by 15 points (33 minus 18), and increases the probability of ... Survey In 1996, the credit has overall been decreasing for 53% of the sample, it has been increasing for 36%, and has been stable for the remaining 11% An increase in indebtedness (of 80% in average) ... constraints The descriptive, statistical analysis in Table indeed confirms that the lower the decline in production (or the higher its increase, in the best cases), the higher the probability of...
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THE SUSTAINABLE DEVELOPMENT OF TREE CROPS AND THE PREVENTION OF VEGETATION FIRES IN SOUTH SUMATRA, INDONESIA pptx

THE SUSTAINABLE DEVELOPMENT OF TREE CROPS AND THE PREVENTION OF VEGETATION FIRES IN SOUTH SUMATRA, INDONESIA pptx

Lâm nghiệp

... smallholder farming remains the main land-use in the peneplains of Sumatra (10 million hectares nationwide) These smallholders retain a direct interest in the preservation of the both forests and the plantations ... extent, the size of the area burnt - and the matching of these with maps of land-use This indicated that most serious and persistent fires originated in logging concessions and agro-industrial ... Sumatra province contains numerous examples of the changes found in all the fire affected provinces of the island: logging in the peneplains and peat forests, development of large industrial forest...
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The financial crisis and the pricing of interest rates in the Irish mortgage market: 2003-2011 ppt

The financial crisis and the pricing of interest rates in the Irish mortgage market: 2003-2011 ppt

Ngân hàng - Tín dụng

... Table summarises the data used in the modelling The price lenders have to pay for their funding is a key variable of interest in the analysis In the case of Ireland up to the end of 2008, lenders ... as the cost of the liquidity funding provided by the ECB and the Irish central bank are also incorporated within the analysis The rest of the paper is outlined as follows: Section provides further ... behaviour of interest rates in their dataset For instance, Sander and Kleimeier (2004) and and De Graeve et al (2007) select the threshold that minimises the residual sum of squares or results in the...
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Cost Recovery and the Crisis of Service Delivery in South Africa doc

Cost Recovery and the Crisis of Service Delivery in South Africa doc

Khoa học xã hội

... commercial, industrial and high-income areas Consider the following The Durban Chamber of Commerce and Industry “has in recent years expressed the concern of its members regarding the increasing cost of ... bulk of it was indirect, extracted unwittingly from the apartheid state in the form of payment boycotts by township residents in the 1980s and early 1990s In spite of the boycotts, the apartheid ... interests The point of departure for any community-controlled development process is that finance and the financial system must serve the interests of poor communities and not the interests of...
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Báo cáo khoa học: Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells doc

Báo cáo khoa học: Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells doc

Báo cáo khoa học

... 11 The effect of creatine on the kinetics of respiration of skinned bers by exogenous ATP at 0.1 and 2.0 lM free calcium At the 0.1 lM calcium concentration, and in the presence of creatine, the ... sigmoidally increasing the active tension in cardiac cells as a result of the formation of actomyosinADP rigor complexes [59] In the presence of the exogenous ATP regenerating system and of high ... turnover of contractile cycles during high workloads and as a result of the presence of creatine kinase and adenylate kinase systems, the channelling of adenine nucleotides and metabolic signalling...
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Báo cáo khoa học: Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells pot

Báo cáo khoa học: Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells pot

Báo cáo khoa học

... bearing in mind that the incorporation of choline into PC might be inhibited by HePC interfering with the biosynthesis of PC, we went on to analyse the enzyme activities involved in this synthetic ... in the tumoral hepatic cell line HepG2, HePC hinders the incorporation of radiolabelled choline into PC, the endproduct of the CDP–choline pathway This reduction in the incorporation of choline ... cells [16] and KB and Raji cells [32], in which the authors showed that APC did in fact interfere with the uptake of choline into the cell, leading to a decrease in PC biosynthesis In the present...
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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo khoa học

... 3, and > h from the start of glucose infusion For the calculation of glycogen C6 changes, data acquired within h of the start of the glucose infusion was not included to avoid any in uence of ... up -regulation of glucokinase and a down -regulation of glucose-6-phosphatase gene expression, suggesting that this biofactor may also be involved in balancing the uptake and release of glucose from the ... the initial rate of label incorporation into glycogen C6 relative to the rate of label incorporation into glycogen C1 reflects the relative isotopic enrichment of Glc6P in the C6 relative to the...
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Báo cáo Y học: Changes in ultrastructure and the occurrence of permeability transition in mitochondria during rat liver regeneration ppt

Báo cáo Y học: Changes in ultrastructure and the occurrence of permeability transition in mitochondria during rat liver regeneration ppt

Báo cáo khoa học

... succinate and phosphate Mitochondria were suspended in the swelling medium and the absorbance of the mitochondrial suspension as a function of time was monitored either in the absence or in the ... Matrix proteins release assay For the assay of the in vitro release of matrix proteins, mitochondria (10 mg proteinÆmL)1) were suspended in the swelling medium, above reported, and incubated at ... at 24 h after PH The increase in the number of lysosomes, even if at a low extent, the presence of autophagosomes and the reduction in the number of mitochondria that we observe in hepatocytes...
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