... low ADH(Vmax) and high Gra3PDH(Vmax) andis similar to a sub regime of extreme JðglycolysisÞ PFK flux control in which CADH approaches 0.2, in that it is correlated with reduced ADH(Vmax) and that ... of metabolite concentration and flux are obtained from populations of yeast cells and so reflect an aggregate of the states of many individual organisms Although no fitted model in this paper individually ... represent natural variability in the yeast population, and we investigated the regions of parameter and variable space described by them Metabolic Fig Schematic of the model yeast glycolytic pathway...
... points of the axis are non-wandering; is the place of delay near fixed points Lemma 3.5 A closed invariant set W is Lyapunov stable if and only if it has a fundamental system of positively invariant ... mechanisms of slow relaxations can be readily mentioned: The delay of motion near an unstable fixed point, and the delay of motion in a domain where a fixed point appears under a small change of parameters ... there are both τ1 -slow relaxations and Ω(x)-bifurcations For A- flows a weaker version of the statement of Theorem 3.12 is valid (A- flow is called a flow satisfying S.Smale A- axiom [68], in regard...
... transplantation and 2) analyzed long term engraftment in multiple organs and the infarct zone as well as the regenerative effects of cell treatment by molecular and mechanistic approaches at ... evaluated on the day of transplantation (day post surgery) and at one and four weeks post transplantation as described [20] Animals were stratified into groups with small, medium and large infarcts, ... ALDHloLin- transplanted animals and never in multiple organs of the same animal (data not shown) Engrafting human cells appeared small and round to oval shaped with a small cytoplasm relative to the...
... inhibition of VCAM-1 expression in cerebral vasculature by anandamide provides a new mechanism that may explain the therapeutic action of increased anandamide tone in neuroinflammatory diseases like ... clinical form of the disease [8] The endocannabinoid system (ECS), consists of endogenous ligands (AEA and 2-AG) and congeners, target receptors, synthesis (NAPE-PLD; DAG lipase), and degradation ... A, Bari M, Granata F, Gasperi V, De Stefano ME, FinazziAgrò A, Strom R: Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial...
... intrathecal application of exogenous TNFα induced mechanical allodynia and thermal hyperalgesia in rats and mice [13-15] Pain hypersensitivity associated with peripheral neuropathy was attenuated ... Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy Diana Spicarova, Vladimir Nerandzic and Jiri Palecek Department of Functional Morphology, ... Committee and were consistent with the guidelines of the International Association for the Study of Pain, the National Institutes of Health Guide for the Care and Use of Laboratory Animals and the...
... Furusho S, Kita T, Katayama N, Abo M, Ohkura N, Herai Y, Hori A, Ishiura Y, Nobata K, Ogawa H, Yasui M, Kasahara K, Nakao S: Comparison of cough reflex sensitivity after an inhaled antigen challenge ... The AgNOR analysis was performed by counting the number of AgNOR (black dots) per cell at a magnification of 1000× (each group n = animals) Analysis of data The secretory basal and stimulated activity ... activity of glandular cells Therefore, an AgNOR-analysis was performed which is related to rRNA transcriptional activity and cellular pro- Page of 10 (page number not for citation purposes) Journal of...
... the scale differences among traits and allowed reliable comparisons of family covariances among different traits Covariance components, for each cambial age and transformed (standardized) traits, ... Cov(Ax, Ay) and CovFxy are the additive genetic covariance and family covariance component between traits X and Y, respectively Approximate standard errors of heritability and new family covariance ... The family covariance between ED and EA was negative at age and positive between ages and 7, which is mainly juvenile wood (Fig 6B) This covariance decreased with cambial age after ring and was...
... stay from day to weeks and serve regional agencies of the Massachusetts Department of Mental Health They have the same mission and similar staffing, for both psychosocial and pharmacological ... beginning of treatment (that is, from the subject's examination by a psychiatrist and formulation ofa treatment plan by the clinical team) Research assistants ('raters'), who were master's level ... Health Organization: International Statistical Classification of Diseases and Related Health Problems: 10th Revision (ICD-10) Volume Geneva, Switzerland: World Health Organization; 2007 20 Laddis...
... analysis PLoS Biol 2005, 3:e334 10 Kobayashi K, Ogura M, Yamaguchi H, Yoshida K, Ogasawara N, Tanaka T, Fujita Y: Comprehensive DNA microarray analysis of Bacillus subtilis twocomponent regulatory ... Berriman M, Tivey A, Patel C, Bohme U, Barrell BG, Parkhill J, Rajandream MA: Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database Bioinformatics 2008, 24:2672-2676 ... DVU0110, and DVUA0057 (each colored differently) have overlapping targets Objects are not drawn to scale This isa conservative list of the most likely targets, and the complete list of peaks is available...
... and drafted the manuscript FG and HK participated in the data analysis and review of the manuscript YN performed project planning, participated in the data analysis and helped to draft the manuscript ... biological role and function of HSV-2 UL56, and its interaction with E3 ligase Nedd4, we visualized and characterized the dynamic intracellular localization of UL56 and Nedd4 using live-cell imaging ... γ-adaptin and δ-adaptin), and partially with marker proteins for Golgi complex proteins (Golgi58K and GM130) and early endosomes (EEA1) Scale bars, 10 μm Page of 13 (page number not for citation...
... infusion, and after 15 minutes of nitric oxide inhalation Data represent the mean ± standard deviation CO, cardiac output; MPAP, mean pulmonary arterial pressure; PVR, pulmonary vascular resistance; ... pulmonary vascular resistance, whereas the cardiac output remained unaltered There was a mean decrease in the mean arterial pressure The systemic vascular resistance fell as well, but the decrease ... elucidate the mechanisms of response and nonresponse to INO in an endotoxin-induced animal lung injury model Materials and methods Animals After approval of the local Animal Research Ethical committee,...
... recurrent abdominal pain and anxiety disorders J Pediatr Psychol 2009, 34:176-186 Kristjansdottir G: Prevalence of pain combinations and overall pain: A study of headache, stomach pain and back pain among ... questionnaire, developed by Audhild Løhre ache and headache as dependent variables First, each factor was included separately as a covariate, adjusting only for gender and grade Thereafter, all covariates ... for sadness, anxiety, stomach ache and headache The left part of Table 2, 3, 4, and show the association of each independent variable, with adjustment for gender and grade In the right part of...
... to animal preparation, performance of experimental work, analysis of mechanical and histological data, statistical analysis, and writing of the manuscript FFC contributed to animal preparation, ... GTC CTG AA-3' and antisense 5'-CTT CAG AGG CAG GAA ACA GG-3'); and glyceraldehyde-3-phosphate dehydrogenase (GAPDH; sense 5'-GGT GAA GGT CGG TGTG AAC- 3' and antisense 5'-CGT TGA TGG CAA CAA TGT ... [9,21] All data were analyzed using ANADAT data analysis software (RHT-InfoData, Inc., Montreal, Quebec, Canada) Echocardiography Volemic status and cardiac function were assessed by an echocardiograph...
... (1990) and Gelfand and Smith variable x can be written as: An estimator of p(!) is: (1990), the marginal density ofa random Thus, the estimator of the marginal density of Qis: e The estimated values ... transformations of random variables to the estimated densities, with minimal additional calculations Examples of estimating the densities of variance ratios andof an intraclass correlation are ... belief&dquo; parameter, and se ) can be interpreted as a u; e (v ) a (su prior value of the appropriate variance In this paper, as in Gelfand et al (1990) we assume the degree of belief parameters, v and...
... and Halliday and Hasan, 1973, 1978, 1989, 1994) had drawn certain attention to this branch by clarifying some “contextual, grammar and cohesional models as well as pragmatic and conversational ... that postulated a double audience, consisting of one party that hearing shall hear and shall not understand, and another party that, 11 when more is meant than meets the ear, is aware both of ... far from the capital city of Havana Havana is the capital of Cuba and forms a distant background to Santiago‘s journey; he uses 14 the lights of the city to find his way back home at night A...
... conformation of DNA, a range of materials are used These materials include mica and polydimethylsiloxane (PDMS) PDMS is widely used in micro- and nanofluidics in the area of lab-on-chip applications ... the physical and chemical phenomena that are important in the condensation of DNA In this thesis, we seek to uncover the behavior of single stranded and double stranded DNA molecules, and explore ... PDMS- and mica-involved experimental strategies allow the investigation of the conformations and real-time responses of DNA 2.1.1.General Features of Mica Mica isa non-swelling clay mineral It has...
... 1111 DATA0 DATA1 DATA2 MDATA Handshake 0010 1010 1110 0110 ACK Handshake NAK Handshake STALL Handshake NYET (No Response Yet) Special 1100 1100 1000 0100 PREamble ERR Split Ping Thereis bits ... of transaction to follow, data packets contain the payload, handshake packets are used for acknowledging data or reporting errors and start of frame packets indicate the start ofa new frame Token ... Data0 Data1 Data packets have the following format Sync PID Data CRC16 EOP Handshake Packets There are three type of handshake packets which consist simply of the PID ACK – Acknowledgment that...
... target than negative opinions We believe that the validation of this hypothesis requires a thorough study, based on a larger amount of data spanning more electoral debates Based on the data analyzed ... Topic-Sentiment Analysis for Mass Opinion Measurement, Hong Kong Acknowledgments Wiebe, Janice, Theresa Wilson, and Claire Cardie 2005 “Annotating expressions of opinions and emotions in language” In Language ... under grant UTA Est/MAI/0006/2009 (REACTION project), and Wilson, Theresa, Janice Wiebe, and Paul Hoffmann 2005 “Recognizing Contextual Polarity in PhraseLevel Sentiment Analysis” In Proc of the...