... symptomatic with a lower Constant score (79) and a higher DASH score (14) Discussion The displaced lateral clavicle fracture is an uncommon fracture Although 15% of all clavicle fractures consist of lateral ... vertical part of the hook and the tip must have contact with the underside of the acromion hereby maintaining reduction of the fractureand withstanding forces applied to the fracture ends Pressure ... arthrosis in patients with conservatively treated lateral clavicle fractures Flinkkila et al [5] described 63 patients with displaced lateral clavicle fractures treated with the clavicle hook...
... doctors and lawyers in the officer corps and to enlisted band members based on nonmilitary training and experience This report explores options for expanding a specific form of lateral entry: lateral ... framework, and evaluates the feasibility of implementing a lateral entry program with the current desired characteris- iii iv Expanding Enlisted Lateral Entry tics The report offers conclusions and ... Corresponding to Lateral Entry Goals and Constraints 15 2.3 Entry Requirements of Lateral Entry Programs Reviewed .16 2.4 Relationship Between Lateral Entry Goals and Training and Experience...
... measurements Patients were treated with either gatifloxacin or levofloxacin Among patients with positive cultures (5 with S pneumoniae, with H influenzae, andwith both H influenzae and M catarrhalis), (87.5%) ... anticholinergic effects and is nonsedative Its adjunctive effect to standard treatment with antibiotics and oral steroids was examined in a double-blind, placebo-controlled RCT in 139 adults withacute rhinosinusitis ... for children and adults with ABRS from geographic regions with high endemic rates ($10%) of invasive PNS S pneumoniae, those withsevere infection (eg, evidence of systemic toxicity with fever...
... without Nonidet P-40 andwith or without ATP (final volume 20 lL) In some experiments, various nucleotide analogs were added at mm final concentration to the EB buffer prior to adding protein and ... twice with buffer N (24 mm Hepes, pH 7.6, with 150 mm potassium acetate, 1.5 mm MgCl2, and 5% glycerol) KCl was added to the lysate to a final concentration of 0.4 m, and the lysate was tumbled with ... mixture was poured into a column and washed sequentially at °C with buffer N plus 0.4 m KCl, buffer N alone, and buffer N with mm imidazole IRP-1 was eluted with buffer N containing 50 mm imidazole...
... simultaneously detected and quantified with the respective complex fraction on the same membrane for each experiment Quantification of purified proteins MBP-NifL and MBPNifA was linear within absolute amounts ... possibly by direct interaction with NifL or the NifL–NifA complex We thus examined: (a) the formation of complexes between NifL, NifA and the primary nitrogen sensor GlnK; and (b) how GlnK effects ... cytoplasm and copurified with the MBPNifL–NifA complexes based on specific binding to either NifL or NifA, or to the NifL–NifA complex In order to confirm the in vivo formation of a trimeric complex...
... individually in ESAT-6 and CFP-10 on complex formation (A) and (D) show 15N-1H-HSQC spectra of 15 N-labeled CFP-10 in the free state and in complexwith unlabeled ESAT-6, respectively (B) and (E) show ... necessary for complex formation with CFP-10 CD scans were recorded for samples in which ESAT-6 and CFP10 were mixed at 25, 30, 35, 40, 45, 50 and 55 °C, and compared with CD scans of the complex formed ... treatment of the complexwith trypsin at °C, one additional band appeared after incubation The largest and smallest of these bands corresponded to CFP-10 and ESAT-6, respectively A third band labeled...
... Experimental procedures Cells and reagents FDC-P1, BAF-3, TF-1, BJAB, A20 and HEK293 cells and primary porcine Achilles tendon fibroblasts (tenocytes) were grown at 37 °C and 5% (v ⁄ v) CO2 with ... treated as follows The cells were either treated with or without cytokines (5% WEHI-3 and 1% GM-CSF) andwith or without inhibitors (LY294002 and U0126) The cells were incubated at 37 °C, 5% ... two bands indicated as phosphorylated Erk1 and Erk2 in FDC-P1 cell extracts (Figs and 2) corresponded to bands detected with anti-Erk serum (data not shown) The nature of the lower two bands,...
... that at least 75% of children have been infected with HPIV1 by years of age [4,5] HPIV1 and show high prevalence and are associated with up to 12% of acute lower respiratory tract infections in adults ... fluid by using ISOGEN (Nippon Gene, Tokyo, Japan) and was then transcribed into cDNA with M-MLV reverse transcriptase (Nippon Gene) and a random primer (Takara Bio Inc., Otsu, Japan) Reverse transcription ... CAT TGA CAA CTT G -3′ (primer HPIV-1USR, position 8034–8061); and second primer pair, 5′- CRA GTS RAG GWA TAG RAG AYT TAG TAT TTG -3′(primer HPIV-1DSF, position 7750–7779) and 5′- GGT TRA TTT CAA...
... treated with various concentrations of curcumin for 24 h The cells were then washed with PBS and incubated with JC-1 working solution for 20 at 37°C in the dark Cells were washed with PBS and resuspended ... (KG1a and Kasumi-1) and in CD34+ primary AML samples We showed that curcumin selectively induced apoptosis in KG1a and Kasumi1 cell lines, as well as in primary CD34+ AML cells, in association with ... D) The IC 50 values at 24, 48, 72, and 96 h were 230.5, 86.9, 60.0, and 35.7 μM for KG1a, 68.5, 46.6, 28.8, and 23.5 μM for Kasumi-1, and 58.3, 26.0, 10.6, and 4.4 μM for U937 cells, respectively...
... the bone); 0.5 mm lateraldisplacement from the central position; mm lateraldisplacement from the central position; 1.5 mm lateraldisplacement from the central position (the lateral edge of the ... medial andlateral edges of the bone Central Central position of the prosthesis in the tibia model; the baseplate is equidistant from the medial andlateral edges of the bone The medial andlateral ... medial andlateral (Figure 6a) The average stress in the interfacial ROI was not influenced by mediolateral baseplate position (Figure 6b) Lateral ROI Stress in the lateral ROI increased significantly...
... a) AP andwith kyphosis of 28-degrees patient with showing1 unstable L1 fracture b) lateral radiogram of a showing preoperative a) AP and b) lateral radiogram of a patient with unstable L1 fracture ... 18 males and 13 females with an average age of 40.6 ± 12.7 (range, 19~63 years) There were 7, 13 and 11 patients who had fractures at T11, T12 and L1 level, respectively 22 patients had injury ... data and revising it critically, KCN has contributed in acquisition of data and analysis and interpretation of data, and JHY has contributed in acquisition and analysis of data All authors read and...
... continue to struggle with the pressures of complexity and commoditization, which have escalated since I wrote the first edition of Mastering the Complex Sale, and while I work with business-to-business ... factor and squander the long-term opportunity We need to address the hopes, fears, and aspirations of our customers and create mutually beneficial relationships Get beyond rote talking points and ... the complex sale Enjoy the read! Enjoy your journey! Mastering Complex Sale the Second Edition I The World in Which We Sell Caught between Complexity and Commoditization If Our Solution Is So Complex, ...
... create and clarify value for their customers and for their employers We see the dynamics of this complex sale challenge every day My colleagues and I spend thousands of hours each year working with ... CAUGHT BETWEEN COMPLEXITY AND COMMODITIZATION questions, such as whether the opportunity actually existed in the first place and why it was pursued at such length and cost When we work with clients ... behind this, but to truly understand the situation, it is important to understand the dynamics at work within complex sales that impact customer decision making and your ability to effectively...
... in a consistent and measureable manner Further, the Prime Process offers sales organizations a platform on which to understand and integrate their professional skills and develop and apply a mental ... selling techniques and they rarely follow their company’s standard sales processes They are not using their company’s sales brochures and other collateral, reciting prepared pitches and presenting, ... organization and are selling at a rate that is three to five times the average We want to understand what they believe, how they think, and how they interact with their customers and colleagues...
... client provides The construction and design of decision trees is a complicated process that becomes more and more difficult and more and more involved as solution complexity rises For instance, ... and miscommunication, the mental framework with which we approach today’s complex sale acts as the enabler of all that follows Without the proper mind-set or point of view, the best systems and ... why change and risk management play such major roles in complex sales The more complex the sale, the more radical the change that the customer must undertake, and the greater the actual and perceived...
... gambling your time and resources on vague and unsubstantiated opportunities and, subsequently, your sales results will be less robust, random, and unpredictable DISCOVER THE PRIME CUSTOMER 94 ... employees approach and perceive their world—the organization’s strategies and business culture, its driving forces and goals, and the attitudes and beliefs that underpin the behavior and decision making ... call and discuss the client’s situation with a considerable degree of understanding and ask some very relevant questions The quality of our research has just as much to with the content and analysis...
... credibility, and their ability to win complex sales is severely compromised The outcome of the sale becomes random 122 DIAGNOSE COMPLEX PROBLEMS and unpredictable When they don’t thoroughly diagnose a complex ... place, and customers know that they are dealing with someone who can be trusted and will treat them with respect The stage is set for the second phase of the Prime Process: Diagnose 5 Diagnose Complex ... includes the facts and figures needed to check for symptoms of the customer’s problem, the information and resources that the customer will bring to the next meeting, and the information and resources...
... valid, and when used with the customer’s numbers, will provide a credible outcome, that the customer is part of the calculation process, and that the customer is willing to ‘‘own’’ the outcome With ... work with customers to determine whether that cost justifies immediate action relative to other issues and opportunities If you are still engaged with the customer at this point in the Prime Process, ... to Buy, and from Whom Is Made During the Diagnosis Conventional salespeople believe the decision to buy is made after they have presented the solution and as they are handling objections and attempting...
... passed through the Diagnose and Design phases In Diagnose, they have understood and confirmed the risks they are facing and their causes, along with the resulting consequences and their financial impact ... salesperson prepares and presents the proposal and the customer accepts it In delivery and implementation of solutions, sales professionals work with colleagues in their own and their customers’ ... special phrases and meanings that make sense to and strike chords in the people who work within them Listen for key phrases and adopt them Echo this language in your proposal and your customers...