acute and chronic myeloid leukaemia
Chapter 104. Acute and Chronic Myeloid Leukemia (Part 1) ppsx
Ngày tải lên :
07/07/2014, 04:20
... in the past by the Food and Drug
Administration (FDA) for marketing based on trials using the FAB criteria.
Acute Myeloid Leukemia
Incidence
The incidence of acute myeloid leukemia (AML) ...
Chemical and Other Exposures
Exposure to benzene, a solvent used in the chemical, plastic, rubber, and
pharmaceutical industries, is associated with an increased incidence of AML.
Smoking and exposure ... years after exposure,
and affected individuals have aberrations in chromosomes 5 and 7. Topoisomerase
II inhibitor–associated leukemias occur 1–3 years after exposure, and affected
individuals...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 2) pot
Ngày tải lên :
07/07/2014, 04:20
... Acute myelomonocytic leukemia
Acute monoblastic and monocytic leukemia
Acute erythroid leukemia
Acute megakaryoblastic leukemia
Acute basophilic leukemia
Acute panmyelosis ...
Acute megakaryoblastic leukemia
Acute basophilic leukemia
Acute panmyelosis with myelofibrosis
Myeloid sarcoma
French-American-British (FAB) Classification
c
Incidence
M0: Minimally differentiated ... myelodysplastic
syndrome/myeloproliferative disorder
Without antecedent myelodysplastic syndrome
III. AML and myelodysplastic syndromes, therapy-related
Alkylating agent–related
Topoisomerase type II...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 3) pps
Ngày tải lên :
07/07/2014, 04:20
... Continuous
activation of Flt3 and downstream target kinases, including signal transducer and
Chapter 104. Acute and Chronic
Myeloid Leukemia
(Part 3)
Immunophenotype and Relevance to the WHO ... associated with younger age are t(8;21) and t(l5;17); with older
age, del(5q) and del(7q). Myeloid sarcomas (see below) are associated with t(8;21)
and disseminated intravascular coagulation ... important in the development of
myeloid and lymphoid lineages. Activating mutations of the gene FLT3 are
present in ~30% of adult AML patients due to internal tandem duplications (ITDs)
in the...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 4) pps
Ngày tải lên :
07/07/2014, 04:20
... Chapter 104. Acute and Chronic
Myeloid Leukemia
(Part 4)
Clinical Presentation
Symptoms
Patients with AML most often present with nonspecific symptoms that
begin gradually or abruptly and are ... they are,
myeloid lineage is virtually certain (Fig 104-1). Poor neutrophil function may be
noted by impaired phagocytosis and migration and morphologically by abnormal
lobulation and deficient ... anemia.
The median presenting leukocyte count is about 15,000/àL. Between 25
and 40% of patients have counts <5000/àL, and 20% have counts >100,000/àL.
Fewer than 5% have no detectable leukemic...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 5) docx
Ngày tải lên :
07/07/2014, 04:20
... Chapter 104. Acute and Chronic
Myeloid Leukemia
(Part 5)
Morphology of AML cells. A. Uniform population of primitive
myeloblasts with immature chromatin, nucleoli in some cells, and primary ... patients, and
about 25% have counts <25,000/àL. Both morphologic and functional platelet
abnormalities can be observed, including large and bizarre shapes with abnormal
granulation and inability ...
patients and cryopreserved for future use as new tests and therapeutics become
available. All patients should be evaluated for infection.
Table 104-
2 Initial Diagnostic Evaluation and Management...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 6) pps
Ngày tải lên :
07/07/2014, 04:20
... achievement of CR. In addition, patients who achieve
Chapter 104. Acute and Chronic
Myeloid Leukemia
(Part 6)
Most patients are anemic and thrombocytopenic at presentation.
Replacement of the appropriate ... entering CR, the length of CR, and
the curability of AML. CR is defined after examination of both blood and bone
marrow. The blood neutrophil count must be 1000/àL and the platelet count
100,000/àL. ... clinical
feature associated with a lower CR rate and shorter survival time. The CR rate is
lower in patients who have had anemia, leukopenia, and/ or thrombocytopenia for
>3 months before...
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Tài liệu Canadian clinical practice guidelines for acute and chronic rhinosinusitis pdf
Ngày tải lên :
19/02/2014, 08:20
... Comparison of the efficacy and tolerability of amoxycillin/
clavulanic acid 875 mg b.i.d. with cefuroxime 500 mg b.i.d. in the
treatment of chronic and acute exacerbation of chronic sinusitis in
adults. ... research tools
and are not currently available in the clinical setting.
Maxillary Sinus Aspirate (MSA) MSA is considered
the gold standard for bacterial recovery in acute and
chronic sinusitis, ... P:
Antibiotics and topical nasal steroid for treatment of acute maxillary
sinusitis: a randomized controlled trial. JAMA 2007, 298:2487-2496.
110. Meltzer EO: Antibiotics and nasal steroids for acute...
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Tài liệu Acute and chronic sinusitis pdf
Ngày tải lên :
19/02/2014, 08:20
... Acute and chronic sinusitis
PLAIN X‐RAYS
Fluid level frontal sinuses
Surgical treatment chronic
Surgical
treatment
chronic
maxillar
y
sinusitis
y
Inferior ... Pharyngeal, laryngeal and ear infections
ã Mucocele
ã Osteomyelitis
Obit l li ti
ã
O
r
bit
a
l
comp
li
ca
ti
ons
ã
Intracranial complications
ã
Intracranial
complications
Acute sinusitis
Acute
sinusitis
... (sinusitis)
Fluid
Level
(sinusitis)
CT SCAN
Complete opacity Rt sphenoid siunus
Treatment of chronic maxillary
sinusitis
Cld llL ’ ti
C
a
ld
we
ll
L
uc
’
s opera
ti
on
Orbital Complications
Orbital...
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Acute and Chronic Sinusitis - A Practical Guide for Diagnosis and Treatment docx
Ngày tải lên :
16/03/2014, 14:20
... causes of and risk factors associated
with sinusitis
ã Differentiate acute from chronic sinusitis
ã Evaluate patients by history, physical exam, appropriate
laboratory and imaging studies, and when ... regimens for acute and
chronic sinusitis
ã Know of the relationships between upper airway
(rhinosinusitis) and lower airway disease (asthma)
37
0031003
Additional Antibiotics for Acute
Bacterial ... 1/2
solution. Turn head to opposite side and repeat process.
– Use once, twice daily or as often as needed
1
Acute and Chronic Sinusitis
A Practical Guide for
Diagnosis and Treatment
...
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Báo cáo sinh học: " Hepatitis B virus (HBV) genotypes in Egyptian pediatric cancer patients with acute and chronic active HBV infection" pptx
Ngày tải lên :
18/06/2014, 18:20
... cancer patients with acute
and chronic liver disease.
Methods: HBV genotypes were determined in 22 patients who had acute forms of liver disease
(AH) and in 48 patients with chronic active hepatitis ... Five cases had
both genotypes A and D, 2 cases had C and D, 2 other
cases had B and D and 2 cases had genotypes B and C. The
distribution of mixed genotypes among AH and CAH
patients is shown in ... distribution between and even within
regions, and are proving to be an invaluable tool in trac-
ing the molecular evolution and patterns and modes of
spread of HBV. Structural and functional differences
between...
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Báo cáo sinh học: " Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: An experimental murine model" pot
Ngày tải lên :
19/06/2014, 08:20
... pathogenesis of the acute
RSV-induced disease process is not completely under-
stood, and their potential role in determining the chronic
consequences of RSV infection, such as AO, AHR and
chronic inflammation ... days after (not shown). Acute and chronic inflammatory infiltrates, surrounding airways and vessels are
demonstrated in RSV-inoculated mice of both strains, on days 5 and 77 after inoculation ... children
and its potential contribution to the development and
maintenance of AHR is a critical question that needs to be
addressed.
In summary, we provide evidence that RSV-induced acute
and chronic...
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