acting beta agonist salmeterol via specific b agonist effect
Báo cáo y học: " Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke" pot
... experiments Membrane expression of TLR4 is upregulated by the longacting beta-< /b> agonist < /b> Salmeterol < /b> via < /b> specific < /b> β -agonist < /b> effect We next examined the effect of the long acting < /b> beta < /b> agonist < /b> salmeterol < /b> ... (Figure 5C), an effect which was confirmed by Laser Scanning Cytometry (Figure 5D) Pre-treatment of cells with the beta-< /b> blocker Butoxamine abrogated the effect of Salmeterol < /b> 10-6 M on membrane expression ... untreated or incubated with salmeterol < /b> over the dose ranges 10-9 to 10-6 M for hours Beta-< /b> agonist < /b> effect was examined by pre-treatment of cells with Butoxamine 0.5 M × 30 minutes prior to salmeterol...
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Báo cáo y học: "Long acting b2-agonist and corticosteroid restore airway glandular cell function altered by bacterial supernatant" pdf
... laboratory MJ is employed by GlaxoSmithKline who markets Seretide, a combination of a long -acting < /b> beta-< /b> agonist < /b> (salmeterol)< /b> and a corticosteroid (fluticasone propionate) FD, FT, BNR, CK, JM, GB, ... (Raytest, Courbevoie, France) Actin and CFTR co-localisation by immunocytochemistry To detect actin by immunofluorescence, we used an affinity isolated antigen specific < /b> antibody obtained from rabbit anti-actin ... viability, airway glandular cells were incubated with increasing concentrations of bacterial supernatant Cell death was evaluated by using the propidium iodide fluorescent probe and cell viability...
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Báo cáo y học: " Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trials" pps
... Hence it is plausible that bronchodilator responsiveness to ipratropium could be affected by beta-< /b> agonist < /b> tolerance Moreover, it is possible that beta-< /b> agonists have a non -specific < /b> effect on airway ... is not overcome by mg of nebulised salbutamol The effect is specific < /b> to beta-< /b> agonists and does not affect the response to ipratropium bromide Patients using long -acting < /b> beta-< /b> agonists may respond ... response to beta-< /b> agonists In practice, many patients are given repeated doses of beta-< /b> agonists via < /b> nebuliser during an acute exacerbation It was not possible to test the effects of repeated nebulisations...
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Báo cáo y học: "Inhaled steroid/long-acting β2 agonist combination products provide 24 hours improvement in lung function in adult asthmatic patients" pps
... screening for randomised patients (n) BDP: 200 mcg bd/400 mcg bd/500 mcg bd Budesonide: 200 mcg bd/300 mcg bd/400 mcg bd/600 mcg bd FP: 100 mcg/250 mcg bd Study B 5/23/15 0/0/21/1 2/8 * the majority ... combination therapies (EDICT): a randomised, double blind comparison of Seretide (50–250 mcg bd Diskus vs formoterol (12 mcg bd) and budesonide (800 mcg bd) given concurrently (both via < /b> Turbuhaler) ... excluded Subjects were also required to stop taking long acting < /b> β2-agonists weeks prior to visit Study B Subjects were required to be receiving between 800–1200 mcg of budesonide or BDP or 400–600...
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Bóa cáo y học: "Reduction in airway epithelial chloride transport in septicaemia related pulmonary oedema reversible by beta agonist application" docx
... then this is another potential mechanism by which beta-< /b> agonists might improve fluid clearance and thus support the findings of our study [1] and the beta-< /b> agonist < /b> lung injury trial [2] Hopefully ... Inhaled beta-< /b> 2 agonist < /b> salbutamol and acute lung injury: an association with improvement in acute lung injury Critical Care 2006, 10:R12 Perkins GD, McAuley DF, Thickett DR, Gao F: The beta-< /b> Agonist < /b> ... randomized controlled trials to demonstrate if beta-< /b> agonists are an effective treatment in ALI and also mechanistic experiments to explain any therapeutic effect Competing interests The authors declare...
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nghiên cứu phương pháp phân tích các chất kích thích tăng trưởng họ beta-agonist trong thịt heo, gan heo, thức ăn nuôi heo bằng phương pháp phân tích sắc ký ghép khối phổ (gc-ms)
... ABC + e- → ABC•+ + 2e- (hình thành ion phân tử) ABC + e- → A+ + BC + 2e- (sự phân mảnh) ABC + e- → AB+ + C + 2eABC + e- → ABC++ + 3e- (ít xảy ra) ABC + e- → A+ + BC + eABC + e- → AB+ + C + eABC ... Clean up m u b ng c t SCX - D n xu t: 1% TMCS + BSTFA ho c HFBA ho c BBA - S d ng máy: GC-SIMMS - Các ion xác nh n m/z: cho BSTFA: 86, 243, 262, 277 cho HFBA: 363, 398, 439, 456 cho BBA: 243, 245, ... electrode Đối với đầu dò b y ion người ta chia làm hai loại: ion hóa b n b n trap ion Sự ion hoá b n Sự ion hóa b n Ngoài b y ion: - Thực việc ion hóa Trong b y ion: Trong b y ion: - Tách ion -...
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Tài liệu Báo cáo khoa học: a-Defensins increase lung fibroblast proliferation and collagen synthesis via the b-catenin signaling pathway doc
... Thr390-phosphorylated GSK 3b (GSK 3b- P-T390), total GSK 3b, active ⁄ dephosphorylated b- catenin, total b- catenin and collagen-I and cell proliferation in lung fibroblasts Lung fibroblasts HFL1 were incubated with ... phenomenon among lung fibroblasts a-defensin-1 and a-defensin-2 increased active ⁄ dephosphorylated b- catenin in lung fibroblasts As shown in Fig 2A ,B, incubation of HFL-1 lung fibroblasts with a-defensin-1 ... GSK 3b, total GSK 3b, active ⁄ dephosphorylated b- catenin, total b- catenin and collagen-I, and cell proliferation were determined As shown in Figs 7A ,B and 8A ,B, the incubation of lung fibroblasts...
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Báo cáo toán học: " Measurement of beta amyloid peptides in specific cells using a photo thin-film transistor" pot
... author: kbsong@etri.re.kr † Contributed equally Email addresses: C-BK: cbkim@etri.re.kr C-JC: cjchae@etri.re.kr H-RS: hyerimgrace@etri.re.kr K-BS: kbsong@etri.re.kr -1- Abstract The existence of beta-< /b> amyloid ... number of photons absorbed within the fluorochrome Subsequently, Pem can be mathematically expressed as follows: (4) Pem = Φ × ( # of absorbed photons ) = Φ (1 − e − Aλ ) , where Aλ is the absorbance ... protect nonspecific antibody bindings in the next step Then, the overnight incubation with a primary antibody (Abcam, Cambridge, MA, USA) was performed for the specific < /b> binding to Aβ peptides...
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Báo cáo y học: "IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis κ synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways" doc
... tested by gel mobility shift assay of radiolabeled oligonucleotide probes representing the NF- B sites in the promoter of (a) IL-6 and (b) IL-8 Arrows indicate probe bands shifted by NF- B binding ... of inhibitor of B in RA synovial fibroblasts [4], indicating that activation of NF- B is involved in IL-17 signaling Studies of IL-1β-stimulated synovial fibroblasts showed that NF- B plays ... and SB203580 were obtained from Calbiochem (Schwalbach, Germany), and pyrrolidine dithiocarbamate (PDTC) was from Sigma (St Louis, MO, USA) Soluble recombinant CD40L (sCD40L) was provided by R&D...
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Báo cáo y học: "Effect of short-acting beta blocker on the cardiac recovery after cardiopulmonary bypass" pot
... beta < /b> blocker had positive effect on the recovery and ventricular arrhythmias in cardiac surgery patients, which indicated beta < /b> blocker was another alternate to benefit the heart rhythm in CPB ... conclusion, esmolol has a positive effect on the cardiac recovery in CPB surgeries List of abbreviations CPB: cardiopulmonary bypass; CABG: coronary artery bridge grafting Acknowledgements We ... potential beneficial effects of beta < /b> adrenergic blockade in the treatment of ventricular fibrillation Eur J Pharmacol 2009, 616:1-6 Jingjun L, Yan Z, Dongdong Z, Guosheng L, Mingwei B: Effect and...
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Báo cáo y học: "Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-B pathways" pps
... described in ‘Materials and Methods’ The surface B7 -1 (A) and B7 -2 (B) molecules were labeled with either anti -B7 -1, B7 -2 and the cell were stained using anti-Vb8.1+8.2FITC, anti-Vb2-PE, anti-Vb2-FITC ... Cell viability (B) Cell viability was evaluated as described in ‘Materials and Methods’ modulated by therapeutic doses of antimicrobial agents [13] Activated macrophages include the inducible ... incubated with anti-TNF-a, anti-IL 1b, anti-IL-6, anti-iNOS, anti-COX-2, anti-p-IBa, or anti-p65 monoclonal antibodies for h and subsequently washed times with PBS After incubation with an AP-labeled...
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Báo cáo y học: "Endotoxin-activated microglia injure brain derived endothelial cells via NF-B, JAK-STAT and JNK stress kinase pathways" docx
... anti- phospho NF- B p65 subunit antibody (rabbit polyclonal, Cell Signaling Technology) by western blot Page of 15 Cell viability assays MTT was used to assay cell viability Trypan blue exclusion ... described [17] IBa in cytoplasmic extracts and NF- B subunit p65 in nuclear extracts were detected by Western blot using specific < /b> antibodies anti-NF-Bp65 and anti-IBa [18] We also assessed NF- B ... PBS containing 0.2% Triton X-100 for 15 Nonspecific binding sites were blocked in blocking buffer (2% BSA and 0.2% Triton X-100 in PBS) for hr The cells were incubated with primary antibody specific...
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Báo cáo y học: "Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-B pathways" potx
... described in ‘Materials and Methods’ The surface B7 -1 (A) and B7 -2 (B) molecules were labeled with either anti -B7 -1, B7 -2 and the cell were stained using anti-Vb8.1+8.2FITC, anti-Vb2-PE, anti-Vb2-FITC ... Cell viability (B) Cell viability was evaluated as described in ‘Materials and Methods’ modulated by therapeutic doses of antimicrobial agents [13] Activated macrophages include the inducible ... incubated with anti-TNF-a, anti-IL 1b, anti-IL-6, anti-iNOS, anti-COX-2, anti-p-IBa, or anti-p65 monoclonal antibodies for h and subsequently washed times with PBS After incubation with an AP-labeled...
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Báo cáo hóa học: " Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice" pptx
... eosinophil numbers in BAL fluid; but the combination of the two drugs was most effective The basis of this synergy and whether the combination will be effective in infants and children affected by exposure ... use of a combination therapy can be very effective in reducing virally-induced asthma exacerbations Abbreviations FP, fluticasone propionate; Sal, salmeterol;< /b> FPS, fluticasone plus salmeterol;< /b> ... PBS baseline reading Bronchoalveolar lavage (BAL) Lungs were lavaged using 500 µl of PBS and the BAL fluid was kept at 4°C until processed BAL cells were centrifuged onto microscope slides by...
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Báo cáo khoa học: Expression level and agonist-binding affect the turnover, ubiquitination and complex formation of peroxisome proliferator activated receptor b pptx
... proteins represent polyubiquitinated PPARb In both cases, ubiquitination was strongly inhibited by GW501516 (lanes and 4) In spite of the readily detectable agonist < /b> effect on FEBS Journal 274 (2007) ... FLAG-PPARb was precipitated by the PPARb-specific antibody (lane 2), and vice versa, that PPARb was coprecipitated by both FLAG-directed antibodies (lanes and 4), suggesting the formation of PPARb oligomers ... To address this question, we established a cell line (3Fb1) stably expressing 3xFLAG-tagged PPARb in a PPARb null background at less than 1% of the PPARb level observed in transiently transfected...
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báo cáo hóa học:" Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation" doc
... purified B cells have not been described Here, we evaluated the in vitro effects of CP-870,893 on peripheral blood B cells from normal donors, including both memory and naïve B cells as defined by ... incubation does not yield more-than-additive effects These results suggest that both memory and naïve B cells can be activated by the drug CP-870,893, and this CP870,893 effect can be increased by ... of global B cell activation as evidenced by significant upregulation of CD86 expression on B cells after infusion [14] (JR and RHV, unpublished observations) This pharmacodynamic effect on B cells...
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Báo cáo khoa học: "nhaled beta-2 agonist salbutamol and acute lung injury: an association with improvement in acute lung injury" doc
... whole blood Infect Immun 1994, 62:2046-2050 43 Basran GS, Hardy JG, Woo SP, Ramasubramanian R, Byrne AJ: Beta-< /b> 2-adrenoceptor agonists as inhibitors of lung vascular permeability to radiolabelled ... rats: reversal by beta-< /b> adrenergic agonist < /b> treatment Am J Respir Cell Mol Biol 2001, 25:554-561 23 Perkins GD, McAuley DF, Thickett DR, Gao F: The Beta < /b> agonist < /b> lung injury trial [abstract] Thorax ... Hall JB: Treatment of bronchospasm by metered-dose inhaler albuterol in mechanically ventilated patients Chest 1995, 107:210-213 26 Benoit D, Vahdewoude K, Colardyn F: Effects of nebulised salbutamol...
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Toàn văn đánh giá hàm lượng các chất b agonist (clenbuterol và salbutamol) trong thức ăn gia súc và dư lượng trong thịt gia súc bằng kỹ thuật sắc ký lỏng ghép khối phổ
... clen 500ppb + sal 500ppb) 1MBK, 2MBK, 3MBK Mẫu thận gà mái nghiệm thức B 1TBK, 2TBK, 3TBK Mẫu thận gà trống nghiệm thức B vi 1MBL, 2MBL, 3MBL Mẫu gan gà mái nghiệm thức B 1TBL , 2TBL, 3TBL Mẫu gan ... sal gan B ng 3.30 Trị số LODtb LOQtb clen thịt heo (a1) B ng 3.30 Trị số LODtb LOQtb sal thịt heo (a2) B ng 3.30 Trị số LODtb LOQtb clen TACN (b1 ) B ng 3.30 Trị số LODtb LOQtb sal TACN (b2 ) Tỉ ... suyễn phổ biến Salbutamol dùng cho người với tên biệt dược Albuterol, Salbutamol…Clenbuterol dùng với tên biệt dược Broncodil, Clenburol, Ventolax, Protovent (Theo tài liệu trang web http://en.wikipedia.org/wiki/Salbutamol)...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25