a pdgf ra signaling suppresses a smooth muscle actin expression in a neonatal mouse lung fibroblast cell line
Báo cáo y học: " Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells" pps
... physiological salt solution (PSS) for 30 to remove extracellular fura 2AM and to activate intracellular fura 2-AM into fura The [Ca2+]i was measured using an xenon lamp (Lambda DG4, Sutter Instrument ... membrane caused by ER depletion is the dominated component of CCE [16] Ca2+ influx via SOC appears to be a determinant in maintaining a sustained increase in [Ca2+]i and regulation of vascular ... proliferation including osteoblasts [6], pancreatic beta cells [7], human myometrial vascular smooth muscle cells [8], rat aortic myocytes [9], rat cardiac myocytes and fibroblasts [10], and skeletal...
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Báo cáo hóa học: " Research Article Nonlinear Synchronization for Automatic Learning of 3D Pose Variability in Human Motion Sequences M. Mozerov, I" pot
... [11] A Nakazawa, S Nakaoka, and K Ikeuchi, “Matching and blending human motions using temporal scaleable dynamic programming,” in Proceedings of the IEEE/RSJ International Conference on Intelligent ... constrained, and these natural constraints lead to highly correlated data in the original space Therefore, we aim to find a more compact representation of the original data to avoid redundancy ... (dashed black line) for the walking action We used b = dimensions for building the PCA space representation explaining the 93% of total variation of training data On the other hand, we are also interested...
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Báo cáo khoa học: " Expression of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in human placenta" doc
... and action mechanism of PACAP in human placenta, the localization of PACAP and its PAC1 receptor in the same areas strongly suggest that PACAP may act as an autoregulator or pararegulator via ... during the pregnancy period In the previous studies, many researchers demonstrated that PACAP acts an autocrine and/or paracrine regulator in various tissues, including ovarian granulose cells, ... and terminal villi As gestation advanced, the expression of PACAP and PAC1 receptor mRNAs was increased in these cells It is known that placenta produces several growth factors such as insulin...
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báo cáo khoa học: "First-in-class, first-in-human phase I results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology meeting" pot
... GI Headache Fatigue Dizziness Headache Nausea 125 mg twice daily 17% SD TBD RAV12 RAAG12 i.v GI cancers Diarrhea Abdominal discomfort Transaminitis Diarrhea Abdominal discomfort Transaminitis ... studies reveal diffuse membrane expression of RAAG12 in human GI cancer cells Binding of RAV12 to RAAG12 induces tumor cell death via oncolysis (direct cell death); in preclinical animal xenograft models ... steady-state serum concentrations of PF-00562271, indicating that PET scanning as a bio-imager may accurately reflect drug bioavailability and potentially clinical response Drugs with intra-nuclear targets...
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Báo cáo y học: "CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs" potx
... R, Varadhrajan V, Gupte N, et al: Extended-dose nevirapine to weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India and Uganda: an analysis of three randomised ... period Cell free virus was investigated by measuring the HIV-1 RNA viral load in lactoserum and plasma Cell- free and cell- associated HIV-1 RNA extraction from lactoserum/plasma and 18 h cell culture ... resting CD4+ T cells and perhaps macrophages It can also be reasonably assumed that HIV-1-AgSCs and cell- associated HIV-1 RNA not originate from additional viral replication owing to the suppressive...
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Báo cáo y học: " Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes" ppsx
... DNA-binding domain in the amino-terminus of p65/RelA by cleavage at a sequence near a caspase-3 cleavage site, leaving a carboxy-terminal fragment that contains two potent transactivation domains ... PMA activates caspase-3 through the PKC signaling pathway and this leads ultimately to apoptosis in a gastric cancer cell line [39], caspases also play a central role in T lymphocyte activation ... Kobayashi S, Yonehara S, Sawai H, Okazaki T, Yamamoto K, Sasada M: Caspases are activated in a branched protease cascade & control distinct downstream processes in Fas-induced apoptosis J Exp Med...
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Báo cáo y học: "Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells" doc
... 5'-CCCAGGACAGGCACAAACAC-3' 5'-TGTTCAAAGCAGGCCCGAG-3' 5'-CGGAACTACGACGGTATCTGATC-3' 5'-AACCTCTACTTCTGCCTTGTCT-3' 5'-CGCCTCTCCTGAACGATACTC-3' 5'-GGAGAACCACCATAATTC-3' 5'-TCTTCCTATTCCTGAACC-3' Page of 14 (page ... clustering and gene ontology analysis of microarray data Figure Hierarchical clustering and gene ontology analysis of microarray data (A) A hierarchical clustering of the 56 genes that are modulated ... (target: 1000) and present calls were determined using MAS 5.0 (Microarray Suite v5.0, Affymetrix, Santa Clara, CA) Results were analyzed using GeneSpring 6.0 (Agilent Technologies, Santa Clara,...
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Báo cáo y học: " Open Access Quantification of the virus-host interaction in human T lymphotropic virus I infection" pdf
... CD4+ cells expressing Tax at a given proviral load is the same in HAM/TSP patients and ACs" in a model independent way (ANOVA assumes a linear relationship between Tax expression and proviral load) ... HAM/TSP and AC proviral load-Tax expression data using linear regression Subjects lying above this line were classed as having a high rate of Tax expression (high frequency of Tax+ cells at a ... proliferation by upregulating cellular genes involved in proliferation and deregulating cell cycle checkpoints This increase in infected cell proliferation results in a net increase in proviral load...
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Báo cáo y học: " Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity" pps
... 241 Baba H, Yamada Y, Mori N, Hayashibara T, Harasawa H, Tsuruda K, Sugahara K, Soda H, Takasaki Y, Tawara M, Hirakata Y, Tomonaga M, Kamihira S: Multiple gammac-receptor expression in adult Tcell ... Y, Hirakata Y, Tomonaga M, Sugahara K, Hayashi T, Dateki N, Harasawa H, Nakayama K: Aberrant expression of caspase cascade regulatory genes in adult T -cell leukaemia: survivin is an important ... 246 Yamada Y, Hatta Y, Murata K, Sugawara K, Ikeda S, Mine M, Maeda T, Hirakata Y, Kamihira S, Tsukasaki K, Ogawa S, Hirai H, Koeffler HP, Tomonaga M: Deletion of p15 and/or p16 genes as a poor-prognosis...
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Cambridge.University.Press.Who.Believes.in.Human.Rights.Reflections.on.the.European.Convention.Oct.2006.pdf
... Buckley and Chapman: Applicants who are mothers The radical feminist agenda: Getting rid of patriarchy A disappointing record on rape: X and Y, SW, Aydin and Stubbings The right to have an abortion: ... Reconstructing Mental Health Law and Policy Gobert & Punch: Rethinking Corporate Crime Harlow & Rawlings: Law and Administration: Text and Materials Harris: An Introduction to Law Harris, Campbell & Halson: ... people at Sussex Craig Barker (Law), Jo Bridgeman (Law), Elizabeth Craig (Law), Zdenek Kavan (International Relations), Charlotte Skeet (Law), Martin Shaw (International Relations) and Richard Wilson...
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Kogan.Page.Managing.Projects.in.Human.Resources.Training.and.Developement.Apr.2006.eBook-DDU.pdf
... British Library Library of Congress Cataloging -in- Publication Data Martin, Vivien, 1947Managing projects in human resources, training and development / Vivien Martin p cm Includes bibliographical references ... volunteer to take part in appropriate training programmes Chris is a newly appointed training manager who works in the HR department and has been asked to manage this project Chris has been asked to ... to adapt the learning materials to local conditions This is how Managing Health Services has been adapted in Hong Kong, Australia, Malaya, Slovakia and Russia This enables revision appropriate...
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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... 5’-TGAAGGAGACCCTGACCAAC-3’; COBRA1 reverse 5’-ATCGAATACCGACTGGTGGA-3’; ANK3 forward 5’-GGAGCATCAGTTTGACAGCA-3’; ANK3 reverse 5’-TTCCACCTTCAGGACCAATC-3’; STAU2 forward 5'-CCGTGAGGGATACAGCAGTT-3'; ... associated with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carcinoma derived cell lines The resistance against anticancer ... ERK-PI3K, AKT, NO, cAMP-PKA, PTEN, G-Protein-MAPK, NGF, and PDGF signaling This finding corroborates the interaction observed between various intracellular signaling pathways and apoptosis induced...
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SCARAB BEETLES IN HUMAN CULTURE
... scarabs in Japanese folk medicine Australia, New Guinea, Melanesia Some Australian aboriginals used scarab beetles both as totems and as food Inasmuch as these nomadic peoples ate almost any animal ... scarabs, although it is not prevalent In Thailand, adults of Copris sp and Onthophagus sp (Scarabaeinae), as well as the adults of Holotrichia sp (Melolonthinae), are eaten (Watanabe and Satrawaha ... be acquired by eating them (imitative magic) To the Aymara of the Lake Titicaca Plateau in Bolivia, a certain scarab beetle was believed to cause madness, and occasionally, in referring to an insane...
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3D Videocommunication Algorithms concepts and real time systems in human centred communication
... Euclidian space in 2D Euclidian space in 3D Projective plane in 2D Projective space in 3D Line is a vector in 2D Line at infinity Camera calibration matrix Rotation matrix Identity matrix Translation ... 17.2 Tracking 17.2.1 Mechanical Tracking 17.2.2 Acoustic Tracking 17.2.3 Inertial Tracking 17.2.4 Magnetic Tracking 17.2.5 Optical Tracking 17.2.6 Video-based Tracking 17.2.7 Hybrid Tracking 281 ... Variable length coding Variable length decoding Very-large-scale integration Virtual reality Virtual retinal display Wave field synthesis Wide ultra-extended graphics array Zero parallax setting...
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ĐỀ ÔN THI HỌC KỲ I in ch hsNăm học 2009
... bin v v th (C) Da vo th (C) bin lun theo m s nghim thc ca phng trỡnh : x + x = m Cõu II (2.0 im) Tỡnh giỏ tr ca biu thc : P = log 5.log 27.log 25 2 Chng minh rng : a a a 2 a a + a 2 a +a ... 1ữ 1 Chng minh rng : ( a >0 ) + 1 = 1 a + a +1 a4 + a8 +1 a a8 +1 a2 a4 +1 Tớnh giỏ tr biu thc : S = 31+log9 + + log + 5log125 27 Cõu III (2,0 im) Cho hỡnh chúp S.ABCD vi ỏy ABCD l hỡnh ... bng a v cnh bờn bng 2a a) Tớnh th tớch ca chúp S.ABC theo a b) Xỏc nh tõm v tớnh bỏn kớnh ca mt cu ngoi tip hỡnh chúp S.ABC II/ PHN T CHN ( im ) Hc sinh chn (cõu IV .a; V .a hoc IV.b; V.b) Cõu IVa:(2...
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TRAFFICKING IN HUMAN BEINGS
... ascertaining the true character of trafficking can we hope to adapt appropriate (7)………… against it Interestingly, routes and patterns of trafficking are not static phenomena They are dynamic, changing ... weak laws, liberal visa regimes and widespread corruption, to ferry Turkish, Iranian, Iraqi, Albanian and Afghan migrants into Europe for £5,000 a head A report from the International Organization ... satisfactorily To roll = a movement from side to side Activity SEX, DRUGS AND ILLEGAL MIGRANTS: SARAJEVO’S EXPORT TRADE TO BRITAIN Read the text Adapted from an article by Ian Burrell in Sarajevo,...
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Introduction of Who Believes in Human Rights
... resource in my world As far as I am concerned, using them strategically is not hypocritical, but a way to attain moral aims in the absence of a more persuasive language in which to articulate claims ... Only the strand of liberalism which values individual autonomy above anything else does not regard individualism as a false aspiration.24 To counteract the individualism inherent in human rights ... 80–101, at 92 Leaving aside that human rights as a religion cannot be rationally validated (i.e proved right), it appears to me that human rights can be and indeed are rationally invalidated (i.e proved...
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Projects in human resources training and developement
... British Library Library of Congress Cataloging -in- Publication Data Martin, Vivien, 1947Managing projects in human resources, training and development / Vivien Martin p cm Includes bibliographical references ... volunteer to take part in appropriate training programmes Chris is a newly appointed training manager who works in the HR department and has been asked to manage this project Chris has been asked to ... to adapt the learning materials to local conditions This is how Managing Health Services has been adapted in Hong Kong, Australia, Malaya, Slovakia and Russia This enables revision appropriate...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf
... clear that AF4 plays a central role AF4 serves as a protein-binding platform for several other proteins to initiate a fundamental cellular process P-TEFb binds to the N-terminal portion of AF4, ... as the mammalian orthologue of the Trithorax protein in invertebrates [6] Disruption of this gene in invertebrates and vertebrates leads to homeotic transformation and nullalleles are incompatible ... MLL-mediated acute leukemia Signaling and MLL-mediated leukemias Very few studies have tried to experimentally investigate signaling pathways that might be important for MLL-rearranged cells As a matter...
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