a mediator of msc self renewal
Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... pathway, the PKB pathway and the Janus kinase ⁄ signal transducer and activator of transcription (JAK-STAT) pathway, to promote proliferation, survival and transformation [56,57] The importance ... pathway modulated by cytokines Cancer Biol Ther 6, 912–919 66 Kuroda J, Kimura S, Strasser A, Andreef A, O’Reilly LA, Ashihara E, Kamitsuji Y, Yokota A, Kawata E, Takeuchi M et al (2007) Apoptosis-based ... protein kinase ⁄ extracellular signal-regulated kinase kinase ⁄ kinases: mechanism of action in vivo, pharmacokinetic ⁄ pharmacodynamic relationship, and potential for combination in preclinical models...
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Báo cáo khoa học: The proapoptotic member of the Bcl-2 family Bcl-2 / E1B-19K-interacting protein 3 is a mediator of caspase-independent neuronal death in excitotoxicity pot
... glutamate or N-methyl-d-aspartate (NMDA) NMDA and glutamate significantly increased neuronal cell death (P < 0.01) z-VAD-FMK alone did not prevent cell death caused by glutamate or NMDA Coapplication ... striata, Tris ⁄ HCl-injected striata and CL uninjected striata from Tris ⁄ HCl-injected rats A 60 kDa band was present in KA-injected striata (Fig 1E); this band was much weaker in CL striata, and ... functional transmembrane domain protected against glutamateinduced neuronal cell death Thus, BNIP3 activation and expression appear to be both necessary and sufficient for atypical neuronal apoptosis...
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báo cáo sinh học:" Systematic inclusion of mandatory interprofessional education in health professions curricula at Gunma University: a report of student self-assessment in a nine-year implementation" ppt
... opinions at the end of each IPE module were also obtained Statistical analysis A multivariate analysis of variance (MANOVA) model was used, and then factor analysis of the responses was performed ... patient outcome, such as family-based cardiovascular disease prevention and quality of care, postoperative pain and functioning, and length of stay in patients receiving total joint arthroplasty ... for a total response rate of 87.1% Cronbach's alpha of 10 items was 0.793, revealing a high rate of internal consistency Factor analysis of the responses The "Department belonged to" was added...
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báo cáo hóa học: " Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults" pptx
... in older adults The data were collected by Statistics Canada under the authority of the Statistics Act Access to the data was granted by Statistics Canada based on a peer-reviewed proposal for ... likelihood estimation (FIML) (available in the Mplus 4.2 [30] software package) by using all available data to assess whether the estimates may have been biased by non-random missing data patterns (n ... Blumenthal JA, Babyak MA, Moore KA, Craighead WE, Herman S, Khatri P, Waugh R, Napolitano MA, Forman LM, Appelbaum M, Doraiswamy PM, Krishnan KR: Effects of exercise training on older patients...
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báo cáo hóa học: " Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia" pdf
... caspase-3: 5'gggcctgaaataccaagtca-3' and 5'-aaatgaccccttcatcacca-3'; Dsip1: 5'-ggtggccctagacaacaaga-3' and 5'-tcaagcagctcacgaatctg-3'; CIDE-B: 5' ctggaactcagctcctccac-3' and 5'- cctccaggaccagtgttagc-3'; ... on arrays were scanned using a Kodak Image Station 2000R (Molecular Imaging Systems, Rochester, NY) and were quantified using GEA analysis suite software (SuperArray) Data were analyzed as relative ... cctccaggaccagtgttagc-3'; caspase-2: 5'- cagctccaagaggtttttcg-3' and 5'- acatccaggggattgtgtgt-3'; Tnfrsf1 2a: 5'-gattcggcttggtgttgatg-3' and 5'-cagtccatgcacttgtcgag-3'; RipK2: 5' cagctgggatggtatcgttt-3' and...
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Báo cáo y học: "Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis" pdf
... Koyama Y, Yoshida K, Tanaka S, Minami A: Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts Relevance to intracellular signaling pathways ... stripped and re-probed with rabbit anti-β-actin to verify equal loading Gelatinase assay Gelatinase activity of RA synovial fibroblast culture media was measured using EnzChek gelatinase assay kits ... USA) Statistical analysis Data were analyzed using the student's t-test, assuming equal variance P values
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Báo cáo y học: "Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation" potx
... Kahata K, Hayashi M, Asaka M, Hellman U, Kitagawa H, Yanagisawa J, Kato S, Imamura T, Miyazono K: Regulation of transβ forming growth factor-β and bone morphogenetic protein signalling by transcriptional ... our laboratory suggests that Wnts may also regulate MSC maintenance [19], as they in the selfrenewal of hematopoietic, neural, intestinal, and skin stem cells [18] Wnt 3a treatment increases adult ... downstream involvement of β-catenin in Wnt regulation of MSC self- renewal Page of 10 (page number not for citation purposes) Arthritis Research & Therapy Vol No Kolf et al MSCs from a variety of mammalian...
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Báo cáo y học: "The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration" ppt
... TGTGGATGCCTCTGGGTATC ADAMTS- Forward: GACCTTCCGTGAAGAGCAGTGT 58 Reverse: CCTGGCAGGTGAGTTTGCAT ADAMTS- Forward: CCTGGCAGGTGAGTTTGCAT 60 Reverse: GGAGAACATATGGTCCCAACGT GAPDH Forward: ACTCTGGCAAAGTGGATG 60 ... to assess gene expression Gene Primer sequence (5’ to 3’) Aggrecan Forward: GAGGTCGTGGTGAAAGGTGT Annealing temperature (°C) 60 Reverse: GTGTGGATGGGGTACCTGAC COL 1A1 Forward: AGGGCCAAGACGAAGACATC ... program for MATLAB software (Natick, MA, USA) by an orthopedic researcher who was blinded to the treatment groups The average of the disc height index (DHI) was calculated as a ratio of the average...
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A study of ziran (self so) in early medieval china 4
... involve a variety of its renditions, such as “ziran guan (view on the nature)”, “ziran shuo (doctrine based on the nature)”, “ziran sixiang (thoughts on the nature)”, “ziran zhuyi (naturalism)”, ... Abstract The term “ziran (Self- so)” has a broad spectrum of meanings in the tradition of the Chinese thoughts and culture, with its own long evolutionary history Contemporary studies on “ziran” ... of “ziran” became an important perspective from which the Han-Wei paradigm shift can be viewed However, scholars’ interpretations of the term, in fact, are vary widely, so much that very different...
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A study of ziran (self so) in early medieval china 5
... 上 A. C Graham(葛瑞汉)将“自然”译作”be so of oneself” 而通常，现代汉语中“自 然”被西方翻译为”spontaneous”, 或作为名词”spontaneity”, ”natural ”, “nature”, Allan Sarah, The Way of water and sprouts of virtue, States University of ... 为了避免术语上的纠缠不清，这里需要与福柯(Michel Foucault)、巴赫金(Mikahil Bakhtin) 等人的话语理论作一切割。本文亦在此意义上借用此一语汇。Schwartz, Benjamin Isadore, The world of thought in ancient China, Cambridge, Mass : Belknap Press of Harvard University Press, ... University of New York Press, Albany, 1997 P115 另外，也有学者将之译作 self- so”, 如 Richard L.Van Houten, Nature and Tzu-jan in Early Chinese Philosophical Literature, Journal of Chinese Philosophy, 15(1988),...
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A study of ziran (self so) in early medieval china 6
... 56-57。在这个意义上， A. C Graham(葛瑞汉)将“自然”译作”be so of oneself” 而通常，现代汉语中“自然” 被西方翻译为”spontaneous”, 或作为名词”spontaneity”, ”natural ”, “nature”, Allan Sarah, The Way of water and sprouts of virtue, States University of ... Dictionary of the Chinese Language in the Canton Dialect (Canton: Office of the Chinese Repository, 1856) 和 Syllabic Dictionary of the Chinese Language (Shanghai: American Presbyterian Mission Press, ... （Walter Henry Medhurst， 1796-1857） 又出版了新的中英字典 Chinese and English Dictionary (Bataia: Parapattan, 1842-1843)。1856 年和 1889 年，美国传教士卫三畏 （Samuel Wells Williams，1812-1884）先后出版了 Tonic Dictionary of...
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A study of ziran (self so) in early medieval china 7
... 齐物论》 ，郭庆藩： 《庄子集释》上册，页 55。 123 Ziporyn, Brook, The Penumbra Unbound: The Neo-Taoist Philosophy of Guo Xiang( Albany: State University of New York Press, 2003), p54 124 萧驰：， 《玄智与诗兴》...
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A study of ziran (self so) in early medieval china 8
... 其注“道法 自然”曰： 道不违自然，乃得其性。法自然者，在方而法方，在圆而法圆，于自然 26 Richard B Mather, The Controversy over Conformity and Naturalness during the Six Dynasties, History of Religions, Vol,9, No,2/3,Nov, 1969-Feb 1970, ... “名教”与“自然”在此意义上形成对立。 “自然与名教之辨” 作为玄学的中心课题，24一直是学界解析魏晋士人思 想及人生取向的主要依据。按余英时先生所论，魏晋士风的转变， “是环绕着 名教与自然的问题而进行的” 25 R.B Mather 在〈六朝自然与名教之辨〉一文 。 22 李泽厚： 《华夏美学》， 《美学三书》 （合肥：安徽文艺出版社，1999），页 346。 23 孙楚（？-294）：，《全晋文》卷...
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A study of ziran (self so) in early medieval china 9
... 曹丕《典论•论文》， 《魏晋南北朝文论全编》 （南京：江苏教育出版社，2004）， 页 15。 Stephen Owen, Reading in Chinese Literary Thought, Cambridge, Massachusetts and London: Harvard University Press, 1992, p3 此书译文可参考王柏华、陶庆梅译： 《中国文论：英译与评论》（上海：上海社会科学出版社，2003），以下同。 ... Reading in Chinese Literary Thought, p95 62 陆机：，张少康：《文赋集释》，页 36。 63 陆机：，张少康：《文赋集释》，页 60。 64 陆机：，张少康：《文赋集释》，页 89。 65 张少康：《文赋集释》注引，页 92。 66 Stephen Owen, Reading in Chinese Literary ... 这两种解读皆见于以往学者的论述。详见张少康：《文赋集释》，页 77-79，注 11。 58 龚鹏程：，《文学批评 的视野》，页 73。 59 Stephen Owen, Reading in Chinese Literary Thought, p.42 132 陆机（261-303）几乎改变了这一论述，此文开篇，即由创作者 的“用心”处着眼。陆机认为，创作冲动来自两方面的刺激，一种是情感受...
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A study of ziran (self so) in early medieval china 11
... 西文（按字母顺序排列） Allan Sarah, The Way of water and sprouts of virtue, States University of New York Press, Albany, 1997 Arthur O Lovejoy, The Great Chain of Being: The Study of the History of an Idea, Cambridge, ... Chappell, David W , ed Buddhist and Taoist Practice in Medieval Chinese Society Honolulu: University of Hawaii Press, 1987 Erik Zü rcher, The Buddhist Conquest of China: The Spread and Adaptation ... University of Hawaii Press, 1994 Holzman Donald, Poetry and Politics: The Life and Works of Juan Chi (A. D 210-263), Cambridge: Cambridge University Press,1976 Kang-i Sun Chang ：Six dynasties poetry...
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Trait Mindfulness as a Mediator of Resilience Depressive Symptom
... Psychological Services, Alpharetta, GA Advanced Therapy Practicum Grady Health System, Atlanta, GA Therapy Practicum Grady Health System, Atlanta, GA Therapy Practicum YWCA of Northwest Georgia, Marietta, ... trauma, tragedy, threats or even significant sources of threat.” As research has accumulated in this area, various factors such as socioeconomic advantage, family history of mental health, maltreatment, ... Coordinator of CPS Undergraduate Courses Georgia State University, Atlanta, GA Instructor for CPS Department (Undergraduate) Georgia State University, Atlanta, GA Advanced Therapy and Clinical Research...
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