... present clinicaltrial evaluated the safety and efficacy of UC-II in the treatment of the knee in OA patients Materials and Methods Study Design This clinicaltrial (Human ClinicalTrial Approval ... Ontario and Corunna, Ontario, Canada Physical assessment, medical history, clinical assessments and blood tests as indicated Screening all dogs experienced a relapse of overall pain, exercise-associated ... (creatinine, blood urea nitrogen, alanine aminotransferase, and aspartate aminotransferase) were noted Following UC-II withdrawal for a period of 30 days, all dogs experienced a relapse of overall...
... three randomized clinical trials and who had usable scale scores and valid hospitalization dates were included in the analysis All patients included in the analysis were treated with paliperidone ... group that was not hospitalized when the open-label phase began Approximately 60% were male, and almost half of each sample had duration of schizophrenia of 10 or more years In all, 91% of patients ... hospital discharge (for the patient group hospitalized at the week assessment) of the open-label phase The two categorical PSP and PANSS variables and the indicator of whether the patient was at a...
... the home and first laboratory acrophases only differed, on average, by 0.03 hours Baseline aMT6s acrophase was compared across treatment and age group via × ANOVA Final aMT6 acrophase was determined ... an individual's aMT6s acrophase and the median aMT6s acrophase for his/her age group These measures were calculated for both baseline and final aMT6s acrophase data Baseline measures of circadian ... ages 20–40), mean and SE Age Group Baseline aMT6s Acrophase Final aMT6s Acrophase Baseline Circadian Malsynch Final Circadian Malsynch Baseline Circadian Dispersion Final Circadian Dispersion...
... behavioral treatment, that includes concurrent individual therapy once a week, family therapy as needed and a multifamily skills training group in an outpatient setting An open clinicaltrial ... Frantic efforts to avoid real or imagined abandonment A pattern of unstable and intense interpersonal relationships characterized by alternating between extremes of idealization and devaluation ... 0.007) as well as stress associated with assessment and therapy (d = 1.60; p = 0.009) Regarding aspects such as family, social contact with peers and physical health, a tendency towards amelioration...
... Hypovolaemia and hypervolaemia or a sudden increase in afterload, as in pulmonary embolism, and mitral or tricuspid valve dysfunction are examples of increased atrial workload that can cause AF Nervous ... RJ, Martin DO, Apperson-Hansen C, Houghtaling PL, Rautaharju P, Kronmal RA, Tracy RP, Van Wagoner DR, Psaty BM, Lauer MS, et al.: Inflammation as a risk factor for atrial fibrillation Circulation ... Martin DO, Sprecher D, Wazni O, Kanderian A, Carnes CA, Bauer JA, Tchou PJ, Niebauer MJ, Natale A, et al.: Creactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms...
... between the sampling point and the arterial puncture site before the actual sample was taken or, when an arterial catheter was not available, in capillary blood with the use of a point-of-care glucometre ... assumed a 25% mortality rate in the control group Statistical analysis Data is presented in absolute numbers and proportions for nominal variables Mean ± standard deviation (SD) or median and interquartile ... peak plasma creatinine > 2.5 mg/dl, Peak plasma urea nitrogen > 60 mg/dl, dialysis or continuous venovenous haemofiltration Table Causes of mortality in the patient group Variable Standard treatment...
... not a replacement for, the clinicaltrial When is aClinicalTrial Appropriate? When is it appropriate to evaluate an NLG system with a large-scale task or effectiveness evaluation which compares ... Many thanks to the rest of the STOP team, and especially to Ian McCann and Annette Hermse for their work in the clinicaltrial Thanks also to Yaji Sripada, Sandra Williams, and the anonymous reviewers ... contrast, measured numerical variables (such as the number of mistakes made by a user when following textual instructions) with substantial standard deviations Another complication was that we wanted...
... body and mind at ease Although empirical evidence is not available, it has been suggested that Qigong has a similar effect to antidepressants (Yu, 1999) This may be because Qigong practice has an ... Gender Male Female Education Illiterate Primary Secondary Tertiary Marital status Single Married—deceased Married—alive Diagnosis COPD CVA RA Parkinson Others Live with whom Family Spouse Alone ... Ltd and stronger self-efficacy Paillard and Nowak (1985) reported that an exercise program was able to increase activity tolerance, improve range of motion and mobility, and improve affect and...
... Drs Samara and Abdalla are postdoctoral fellows at the National Cancer Institute Author details Vaccine Branch, NCI, NIH, Bethesda, MD, USA 2Medical Oncology Clinical Research Unit (MOCRU) at the ... Interferon alpha-2b compared with Interferon alpha-2b alone for metastatic renal-cell cancer J Urol 2002, 168:875 Hayakawa K, Salmeron MA, Parkinson DR, Markowitz AB, von Eschenbach AC, Legha SS, Balch ... 5Biostatistics and Data Management Section, CCR, NCI, NIH, Bethesda, MD, USA 6Department of Pharmacy, Clinical Center, NIH, Bethesda, MD, USA Authors’ contributions OER analyzed the data and drafted the manuscript...
... evidence that trastuzumab may synergize with specific T-cells [12], making a combinatorial approach with vaccination and trastuzumab an attractive clinical treatment modality pDNA immunization has several ... immunotherapy, such as plasmid DNA (pDNA) vaccination, is an alternative approach to antibody therapy and several properties make Her2 a promising tumor vaccine candidate [10,11] While trastuzumab seems ... Results Patient characteristics and clinical observations Eight women with a mean age of 57.5 years were accrued in this study Patient characteristics are summarized in Table All patients had advanced...
... Nakayama H, Hirono S, Sakiyama O, Takahashi K, Miyazaki H, Hashimoto S, Daikukhara Y: Purification and partial characterization of hepatocyte growth factor from plasma of patients with fulminant ... S, Gohda E, Nakayama H, Takahashi K, Sakiyama O, Miyazaki H, Sugihara J, Tomita E, Muro Y, Daikuhara Y, Hashimoto S: Clinical significance of human hepatocyte growth factor in blood from patients ... male Wistar rats, seven weeks of age, were obtained from Japan Farm (Kagoshima, Japan) and Charles River Laboratories Japan Inc (Yokohama, Page of 12 Japan), respectively The animals were maintained...
... Politècnica de València, C Vera s/n, 46022 Valencia, Spain 2Servicio de Neurorrehabilitación de los Hospitales NISA Valencia al Mar y Sevilla Aljarafe, Fundación NISA, Valencia, Spain Ciber, Fisiopatolog a ... that eBaViR is feasible, safe and potentially efficacious in enhancing standing balance Methods Participants Seventy-nine hemiparetic patients who had sustained an ABI and were attending a rehabilitation ... This clinicaltrial was carried out in a specialized neurorrehabilitation service of a large metropolitan hospital Each patient participated in a total of 20 one-hour-sessions of rehabilitation and...
... Clinical Research Scholars Program Grace John-Stewart was an Elizabeth Glaser Paediatric AIDS Foundation (EGPAF) Scientist, and Dorothy Mbori-Ngacha had an EGPAF International Leadership Award Antiretroviral ... PENTA trial Pediatr Infect Dis J 2003, 22(1):56-62 Puthanakit T, Oberdorfer A, Akarathum N, Kanjanavanit S, Wannarit P, Sirisanthana T, Sirisanthana V: Efficacy of highly active antiretroviral ... Stanley K, Morse EV, Krogstad PA, Nachman S, Pediatric AIDS Clinical Trials Group Adherence Subcommittee Pediatric AIDS Clinical Trials Group 377 Study Team: Reported adherence as a determinant...
... monoclonal antibody WF6 A mouse monoclonal antibody WF6 was raised against a shark cartilage aggrecan preparation and a quantitative ELISA for the epitope recognized by monoclonal antibody WF6 was ... pro-inflammatory factors, modify the cellular death process and improve the anabolism/catabolism balance of extracellular cartilage matrix [12,13] At the same time it has proven to have a positive ... National Research Council of Thailand (Research program of drug, chemical, medical material and equipment) References Amin AR, Attur MG, Thakker GD, Patel PD, Vyas PR, Patel RN, Patel IR, Abramson...
... Clinical Immunology Auckland City Hospital, Park Rd, Grafton, Auckland New Zealand, 2LabPlus, Auckland City Hospital, Park Rd, Grafton, Auckland New Zealand and 3Central and Southern Regional Genetic ... XHIM was suspected He was treated with Co-trimoxazole and made a Ameratunga et al Allergy, Asthma & Clinical Immunology 2010, 6:12 http://www.aacijournal.com/content/6/1/12 A Normal Page of B Patient ... symptomatic primary immune deficiency disorder in adults Patients present with hypogammaglobulinemia, which is associated with an increase in autoimmunity, malignancy and allergy Approximately Ameratunga...
... continuous variables were evaluated using an analysis of covariance (ANCOVA) model, with treatment and country as factors and baseline score as a covariate Changes from baseline are presented as leastsquares ... interaction as factors and baseline value as a covariate An unstructured variance-covariance matrix was employed for this analysis Between-treatment-group differences in benzodiazepine use and ... received at least one dose of double-blind study medication and had both baseline and at least one post-baseline efficacy assessment Statistical analysis Analyses compared the three paliperidone palmitate...
... meta-analyses in pain using simulations of individual patient data Pain 2000, 85:415-424 Sterne JA, Gavaghan D, Egger M: Publication and related bias in meta-analysis: power of statistical tests and ... statistical analyses, and protocol amendments Full clinicaltrial reports were not available for eight trials, but extensive clinicaltrial summaries were provided Information was extracted directly ... and any comparator, placebo, rofecoxib, or NSAIDs For paracetamol there were only four events Oedema at any site Oedema was reported in various ways in the trials, occasionally just as oedema,...
... Canarias Ofra s/n, La Cuesta 38320-La Laguna Espa a 4Hematology Laboratory Hospital Universitario de Canarias Ofra s/n, La Cuesta 38320-La Laguna Espa a 5Biochemical laboratory Hospital Universitario ... de Canarias Ofra s/n, La Cuesta 38320-La Laguna Espa a Cardiac Surgery Department Hospital Universitario de Canarias Ofra s/n, La Cuesta 38320-La Laguna Tenerife Espa a Jiménez et al Journal ... Universitario de Canarias Ofra s/n, La Cuesta 38320-La Laguna Espa a 2Nephrology Department Hospital Universitario Carlos Haya, 29010-Málaga Espa a 3Mixed Research Unit Hospital Universitario de Canarias...