7 examples of centrally acting skeletal muscle relaxants
Báo cáo y học: " Module-based multiscale simulation of angiogenesis in skeletal muscle" doc
... in human skeletal muscle Am J Physiol Regul Integr Comp Physiol 2004, 2 87: R3 97- 402 74 Gavin TP, Drew JL, Kubik CJ, Pofahl WE, Hickner RC: Acute resistance exercise increases skeletal muscle angiogenic ... 271 :H721 -73 7 69 Breen EC, Johnson EC, Wagner H, Tseng HM, Sung LA, Wagner PD: Angiogenic growth factor mRNA responses in muscle to a single bout of exercise J Appl Physiol 1996, 81:355-361 70 ... 8:191-220 17 Mac Gabhann F, Popel AS: Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal muscle Am J Physiol Heart Circ Physiol 20 07, ...
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THE EFFECTS OF CHROMIUM ON SKELETAL MUSCLE MEMBRANE/CYTOSKELETAL PARAMETERS AND INSULIN SENSITIVITY
... eight weeks of HF feeding As observed in other insulin-resistant animal models, skeletal muscle from HF-fed mice displayed membrane cholesterol accrual and loss of F-actin Skeletal muscle from ... understand the actions of insulin how these processes become deranged in insulin resistance The focus of this thesis research was to dissect membrane/cytoskeletal parameters of skeletal muscle insulin ... exocytic recruitment of intracellular GLUT4 storage vesicles (GSVs) to the plasma membrane (PM) of skeletal muscle and fat cells (25, 27) This stimulated redistribution of intracellular GSVs...
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Tài liệu Báo cáo khoa học: Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle pdf
... 32.93 32 .75 43.26 39 .79 42.38 29.63 27. 04 20.69 18.15 5.8 5.2 5.2 5.2 4 .7 4 .7 6.6 8.8 5.2 6.9 6.9 5.0 4.1 P 077 25 P99041 P31001 P99041 P5 877 4 P5 877 1 P 073 10 Q9CP09 P99041 P16015 P 177 51 P05 977 P20801 ... Excitation-contraction-relaxation cycle: Role of Ca2+regulatory membrane proteins in normal, stimulated and pathological skeletal muscle fibres (review) Int J Mol Med 1, 677 –6 97 53 Duncan, C.J (1 978 ) Role of intracellular ... ÔStainsAllÕ analysis of Fig and the 1D immunoblotting of Fig As the full-length Dp4 27 isoform of dystrophin does not enter the second dimension of conventional 2D gels, the expression level of a-dystroglycan...
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Tài liệu Báo cáo khoa học: Effect of gadolinium on the ryanodine receptor/ sarcoplasmic reticulum calcium release channel of skeletal muscle docx
... Found (OTKA T 0 377 27 and TS 04 077 3), by the Hungarian Ministry of Health (015 ⁄ 2001) and by the European Union (HPRN-CT-2002-00331) We also thank Prof Varda Shoshan-Barmatz of Ben Gurion University ... presence of 18 nm ryanodine and the amount of ryanodine bound was plotted against the concentration of the gadolinium (Fig 7) Fitting of data points with the Hill equation revealed a Kd value of 14 .7 ... parameters of IC 50 ¼ 5.65 lM and nHill ¼ 4 .71 Number of experiments is shown at each point 465 Effect of gadolinium on RyR1 tion of 5.6 ± 0.3 lm for Gd3+ and a Hill coefficient of 4 .7 ± 0.8 We...
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Báo cáo khoa học: Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling pot
... upregulation of slow muscle genes in limb muscles Neurogenetics 7, 81–91 Barash I, Bang ML, Mathew L, Greaser ML, Chen J & Lieber RL (20 07) Structural and regulatory roles of the muscle ankyrin ... the TA muscle of normal mice One month after injection, direct observation of the skinned injected muscle using confocal fluorescence microscopy allowed the visualization of a high level of YFP ... standardization of the loading (D) Weights of injected TA muscles (n = 13) were compared to those of control samples No significant difference was observed (E) Histological analyses of muscles Frozen...
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Báo cáo khoa học: Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma pot
... 62.5 91.3 58.3 99.9 11.5 ± 6.2 4.8 5.2 ± 2.0 34 4 .7 ± 0 .7 1.2 2 .7 ± 2.5 7. 7 59.1 75 .0 48.0 77 .3 a Values indicate the percentage of reduction of creatine ⁄ CK in normal and malignant samples as ... Immunoblot of CK isoforms of different post-operative human tissues (A) Immunoblot of MCK (a) and sMitCK (b) of normal muscle (N) and fibrosarcoma (T) tissue (B) Immunoblot of BCK (a) and uMitCK (b) of ... Inhibition of the mitochondrial permeability transition by creatine kinase substrates Requirement for microcompartmentation J Biol Chem 278 , 177 60– 177 66 27 Annesley TM & Walker JB (1 978 ) Formation...
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Báo cáo khoa học: Mapping contacts between regulatory domains of skeletal muscle TnC and TnI by analyses of single-chain chimeras potx
... pellet of TnC(1–91)–TnI(98–1 47) after h of induction; lane 5, TnC(1–91)–TnI(98–1 47) after purification; lane 6, Molecular mass markers FEBS Journal 272 (2005) 77 9 79 0 ª 2005 FEBS A O Tiroli et al of ... the investigation of activity [ 27] , the creation of antibody chimeras [28], and the study of Table The ratios of the volumes (V) of the models built by SAXS and of the structure of TnC(1–91) (1SKT) ... last residues of TnI not interact with TnC We suggest FEBS Journal 272 (2005) 77 9 79 0 ª 2005 FEBS 78 5 Contacts between skeletal TnC and TnI regulatory domains that the main function of this region...
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Báo cáo Y học: Fluorescence study of the high pressure-induced denaturation of skeletal muscle actin pdf
... rabbit muscle ®bers Proc Natl Acad Sci USA 88, 73 23 73 27 Fortune, N.S., Geeves, M.A & Ranatunga, K.W (1994) Contractile activation and force generation in skeletal rabbit muscle ®bres eects of hydrostatic ... effect of a small amount of HMM, which stimulated fragmentation of F-actin, as reported by Ikeuchi et al [ 27] Interestingly, higher pressures (> 350 MPa), the intensities of ¯uorescence of HMM ... Role of nucleotide hydrolysis in the dynamics of actin ®laments and microtubules Int Rev Cytol 1, 139± 170 Bombardier, H., Wong, P & Gicquaud, C (19 97) Eect of nucleotides on the denaturation of...
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Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf
... transcription of murine 129SVter skeletal muscle RNA (primers indicated in FEBS Journal 277 (2010) 4322–43 37 ª 2010 The Authors Journal compilation ª 2010 FEBS L Laure et al Regulation of CARP by ... Lanfranchi G et al (2001) Characterization of human skeletal muscle Ankrd2 Biochem Biophys Res Commun 285, 378 –386 FEBS Journal 277 (2010) 4322–43 37 ª 2010 The Authors Journal compilation ª 2010 ... Purification of native p94, a FEBS Journal 277 (2010) 4322–43 37 ª 2010 The Authors Journal compilation ª 2010 FEBS 4335 Regulation of CARP by calpain 46 47 48 49 50 51 52 53 54 55 56 57 58 59 L...
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Báo cáo hóa học: " Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients" docx
... mir-206 (Assay n 4 373 092), hsa- mir-181a (Assay n 4 373 1 17) , hsa- mir-181b (Assay n 4 373 116), hsa- mir181c (Assay n 4 373 115), hsa- mir-133a (Assay n 4 373 142), hsa- mir-133b (Assay n 4 373 172 ), hsa- mir-103 ... Fold change values of miR-206: DM1-1 = 3 ,73 ; DM1-2 = 7, 02; DM1-3 = 7, 77; DM1-4 = 2 ,70 ; DM1-5 = 1,20; DM1-6 = 13,22; DM1 -7 = 1,95 Gambardella et al Journal of Translational Medicine 2010, 8:48 http://www.translational-medicine.com/content/8/1/48 ... over-expression of miR-206 (DM1-1 fold change 3 ,73 , DM1-2 fold change 7, 02, DM1-3 fold change 7, 77, DM1-4 fold change 2 ,70 , DM1-6 fold change 13,22) After densitometric analysis of each band, we...
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Báo cáo hóa học: "Assessment of skeletal muscle fatigue of road maintenance workers based on heart rate monitoring and myotonometry" docx
... 40 ± 180 ± 81 ± 25 ± 67 ± 20–60 173 –1 87 65– 97 17 36 56 78 30 ± 172 ± 76 ± 25 ± 62 ± 30–60 165–180 60–92 19–28 50 74 Page of (page number not for citation purposes) Journal of Occupational Medicine ... is the mass of the testing end of myometer; amax is the maximal amplitude of oscillation, and ∆l is the depth of the displacement of the testing end Measurements for determination of muscle tone ... of the skeletal muscle may provide new insights into muscle function and can help to diagnose the stage of pathological processes of muscles grip The testing end (mass 20 grams) of the computerized...
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báo cáo hóa học:" Isokinetic eccentric exercise can induce skeletal muscle injury within the physiologic excursion of muscle-tendon unit: a rabbit model" doc
... properties of skeletal muscles, even within the physiologic range of the excursion of the muscle- tendon unit 22 Acknowledgements 23 The authors sincerely thank the National Science Council, Republic of ... during stretch of active frog's muscle J Physiol Lond 1 978 , 276 :449-65 MuCully KK, Faulkner JA: Characteristics of lengthening contractions associated with injury to skeletal muscle fibers J ... to toad skeletal muscle J Muscle Res Cell Motl 1998, 19:2 37- 45 Sun JS, Tsuang YH, Cheng CC, Hang YS, Liu TK: The effect of nerve function on the failure mechanism of the triceps surae muscle by...
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báo cáo hóa học: " Influence of dietary state and insulin on myocardial, skeletal muscle and brain [18F]fluorodeoxyglucose kinetics in mice" pptx
... in rodents J Nucl Med 20 07, 48: 277 -2 87 Shimoji K, Ravasi L, Schmidt K, Soto-Montenegro ML, Esaki T, Seidel J, Jagoda E, Sokoloff L, Green MV, Eckelman WC: Measurement of cerebral glucose metabolic ... a ramp filter and a cutoff frequency of 0.5 of the Nyquist frequency to obtain an image pixel size of 0.4 × 0.4 × 0.8 mm and an inter-plane spacing and slice thickness of 0.8 mm in a 128 × 128 ... and after Bonferroni correction Ki; correlation coefficients of least square fits averaged R2 = 0.984 ± 0.0 07 Examples of Patlak plots of a nonfasted and an insulin treated mouse are shown in Figure...
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Examples of VHDL Descriptions phần 7 pptx
... http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html (66 of 67) [23/1/2002 4:15:10 ] Examples of VHDL Descriptions http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html ( 67 of 67) [23/1/2002 4:15:10 ] Centre ... http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html (65 of 67) [23/1/2002 4:15:10 ] Examples of VHDL Descriptions entity priority is port(I : in bit_vector (7 downto 0); inputs to be prioritised A : out ... http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html (64 of 67) [23/1/2002 4:15:10 ] Examples of VHDL Descriptions end xorg; architecture only of xorg is begin p1: process(in1, in2) variable val :...
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Examples of VHDL Descriptions phần 7 doc
... http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html (66 of 67) [23/1/2002 4:15:10 ] Examples of VHDL Descriptions http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html ( 67 of 67) [23/1/2002 4:15:10 ] Centre ... http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html (64 of 67) [23/1/2002 4:15:10 ] Examples of VHDL Descriptions end xorg; architecture only of xorg is begin p1: process(in1, in2) variable val : ... http://www.ami.bolton.ac.uk/courseware/adveda/vhdl/vhdlexmp.html (65 of 67) [23/1/2002 4:15:10 ] Examples of VHDL Descriptions entity priority is port(I : in bit_vector (7 downto 0); inputs to be prioritised A : out...
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Báo cáo y học: "Insulin alleviates degradation of skeletal muscle protein by inhibiting the ubiquitin-proteasome system in septic rats" pps
... regulation of skeletal muscle hypertrophy and atrophy Curr Top Microbiol Immunol 2010, 346:2 67- 78 30 Stitt TN, Drujan D, Clarke BA, et al: The IGF-1/PI3K/Akt pathway prevents expression of muscle ... of Jiangsu Province (No BK20 075 73), and the Research Fund for the Doctoral Program of Higher Education of China (No 200802841005) Authors’ contributions QC and TG participated in collection of ... mechanism of muscle protein breakdown during sepsis and other catabolic conditions Ann Surg 19 97, 225(3):3 07- 16 Klaude M, Fredriksson K, Tjader I, et al: Proteasome proteolytic activity in skeletal muscle...
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báo cáo khoa học: " Metabolic adaptation of skeletal muscle to high altitude hypoxia: how new technologies could resolve the controversies" pdf
... activation of a number of transcriptional pathways [20,21] Overexpression of PGC-1α in mouse skeletal muscle leads to a proliferation of fatigue-resistant type I muscle fibers [22] Muscle wasting ... function [ 27] In the skeletal muscle of lowlanders acclimatized to 4,559 m, levels of mTOR were decreased [28], possibly indicating a suppression of mitochondrial biogenesis via downregulation of PGC-1α ... formation of slow-twitch muscle fibres Nature 2002, 418 :79 7-801 Hoppeler H, Kleinert E, Schlegel C, Claassen H, Howald H, Kayar SR, Cerretelli P: Morphological adaptations of human skeletal muscle...
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báo cáo khoa học: " Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia" pdf
... Regression P-value -0 .74 0.82 0.64 0 .7 0.65 0.6 0. 67 0.69 -0.51 0.50 0.50 0. 67 0 .72 0.51 0.53 0. 47 0.03 0.01 0.02 0.00 0.00 0.02 0.01 0.03 0.26 0.45 0.10 0. 17 0.13 0. 07 0 .70 0.40 NS 0.06 NS NS ... Age (years) 45(2) 67( 2)
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Báo cáo y học: " No effect of short-term amino acid supplementation on variables related to skeletal muscle damage in 100 km ultra-runners - a randomized controlled trial" potx
... Intake of carbohydrates (g) - 3,848 (1,369) 75 5 .7 (354.8) - 4,894 (1,641) 608.8 (326.4) Intake of protein (g) 79 .9 (12 .7) ** 26 .7 (22.0) 5.1 (4.8) 7. 0 (7. 1) Energy intake (kcal) Intake of fat ... 168.3 (61 .7) 4,582.5 (3,150.3) 4,414 (3,1 07) ** 1 57. 8 (74 .5) 3,861.5 (2,3 57. 8) 3 ,70 3 (2,340) ** 71 1 (1,065) 6.2 (1.4) 10.6 (2.1) 4.4 (1.6) ** 5.9 (1.5) 9.5 (1.6) 3.6 (1.5)** 0.8 (0.6) 50.2 ( 17. 8) ... protein (7. 76% + 1.94%) every 15 until fatigue The combined intake of carbohydrate and protein enhanced cycling performance [16, 17] and reduced ratings of muscle soreness [14] The ingestion of amino...
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Báo cáo y học: " A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease" pot
... 23.5 (4.4) 67. 1 (15.0) 46 .7 (8.3) 61.5 (19.6) 89.2 (30.2) 65.5 (9.9) 40.5 ( 17. 9) 39.8 (19.9) 181 (32) 5.2 (1.1) 9.4 (1.4) 34.8 (1.5) 66.3 ( 17. 9) 24.3 (5.2) 70 .5 (15 .7) 47. 5 (8.3) 67. 4 (19.5) 98.9 ... (9.4) 36.0 (18.4) 40.1 (19.3) 176 (41) 5.2 (0.9) 9.4 (1.6) 33.3 (1.5)* 62.3 ( 17. 7)* 24 .7 (5.4) 71 .4 (15.9) 47. 3 (7. 9) 69.9 (21.9) 100.0 (44.3) 36.3 (19.4) 40.5 (20.0) 175 (39) 5.2 (0.9) 9.2 (1.4) ... worse prognosis [6] Skeletal muscle is a major component of fat free mass and skeletal muscle depletion is itself associated with reduced exercise capacity [7- 9], while thigh muscle bulk has been...
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