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6 specific anti inflammatory agents

báo cáo hóa học:

báo cáo hóa học: " Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised" potx

Hóa học - Dầu khí

... 1.0 0.71 9.5 ± 2.5 6. 8 ± 2.7 0.71 9 .6 ± 2.1 6. 9 ± 1.7 0.73 8.5 ± 2.2 5.2 ± 1.5* 0 .61 8.3 ± 1.5 4.7 ± 0.7* 0.57 9.9 ± 0.9 7.2 ± 1.3 0.73 10.5 ± 2.0 7.2 ± 1.8 0 .68 9.2 6. 5 0.71 18 .6 7.8 0.42 Values ... Neurosci 2000, 20 :68 62 -68 67 Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE: Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses ... films Three antibodies were used: rat anti- mouse GFAP (1: 5000, clone MAB 2.2B10, provided by Virginia Lee); mouse antiAPP C-terminus (1: 1000, clone C1 /6. 1, ref 24), and rabbit anti- human actin...
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Báo cáo y học:

Báo cáo y học: "Salivary gland derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein" pptx

Báo cáo khoa học

... mechanism of anti- inflammatory action from Page of 11 corticosteroids and nonsteroidal anti- inflammatory drugs (NSAIDs) NSAIDs and corticosteroids have become the mainstay of anti- inflammatory agents ... [66 ] Hence feG and its analogues appear to represent a new class of anti- inflammatory agents which act on immune cells, the central regulators of all inflammation The term “Immune Selective Anti- Inflammatory ... Curr Med Res Opin 2008, 24: 163 5- 164 3 60 Cullinan MP, Ford PJ, Seymour GJ: Periodontal disease and systemic health: current status Aust Dent J 2009, 54(Suppl 1):S62 -69 61 Lund EM, Armstrong PJ,...
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Báo cáo hóa học:

Báo cáo hóa học: "Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a prospective study" docx

Hóa học - Dầu khí

... treatment 155.5 (5.4) 31.1 (4.8) 3.2 (1.2) 0.2 (0.1) 0 .6 (0.3) 40 (18) 67 (18) 66 (20) 34 (17) 0. 966 0.770 0.910 0.984 0.822 0 .60 4 0.597 0.595 0 .62 8 Median (quartiles) WOMAC raw change within transition ... 1.18 0 .61 + 1.05 1. 26 1.38 3.92* 0 .60 + 3.39 1.72+ 1.92+ 0.58+ 0.29* 0 .61 –2.13 0 .63 –2.18 0.28–1.30 0.49–2.25 0 .68 –2.45 0.59–3.21 1.59–9 .67 0.32–1.13 0.31–38.2 0.91–3.25 0.81–4.51 0.27–1. 26 0.12–0.71 ... 1.15–4.19 1. 06 5.73 0.24–1 0.09–0.41 0.43* 0.41 0.81 1.59+ 0.75 0.47* 0.75 2.25+ 0 .67 + 18.2 0 .63 0.51+ 1.47 1. 56+ 0.22–0.82 0.21–0.77 0.43–1.49 0. 76 3.21 0. 36 1.51 0.23–0.97 0.39–1.72 0. 86 5.85 0.35–1.21...
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TSG-6: AN INDUCIBLE MEDIATOR OF PARACRINE ANTI-INFLAMMATORY AND MYELOPROTECTIVE EFFECTS OF ADIPOSE STEM CELLS

TSG-6: AN INDUCIBLE MEDIATOR OF PARACRINE ANTI-INFLAMMATORY AND MYELOPROTECTIVE EFFECTS OF ADIPOSE STEM CELLS

Y khoa - Dược

... to quantify secretion of TSG -6 from human and murine ASC To study the importance of TSG -6 to specific activities of ASC, TSG -6 was knocked down in human ASC by siRNA Murine ASC from TSG -6- /- ... TSG -6 in Inflammatory Diseases The inducibility of the TSG -6 gene by the proinflammatory cytokine TNFα suggested a possible association with inflammatory processes and a potential role in inflammatory ... recombinant human TSG -6 exhibited equivalent effect as 1 .6 X 1 06 human BMSC in reducing total cell numbers in the exudate.47 In addition, the antiinflammatory activity of TSG -6 comparable to BMSC...
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Role of Non-Steroidal Anti-Inflammatory Drugs in Gynecology potx

Role of Non-Steroidal Anti-Inflammatory Drugs in Gynecology potx

Sức khỏe phụ nữ

... steroidal anti- inflammatory drugs on the action of misoprostol in a regimen for early abortion Contraception 1997, 56, 165 – 168 Fiala, C.; Gemzell-Danielsson, K The effect of non steroidal anti- inflammatory ... nonsteroidal anti inflammatory drugs Br J Rheumatol 19 96, 35, 458– 462 17 Akil, M.; Amos, R.S.; Stewart, P Infertility may sometimes be associated with NSAID consumption Br J Rheumatol 19 96, 35, 76 78 18 ... Farquhar, C.;Derks R.S Nonsteroidal anti- inflammatory drugs for primary dysmenorrhoea Cochrane Database Syst Rev 2010, 1, CD001751 Dawood, M.Y Nonsteroidal anti- inflammatory drugs and changing attitudes...
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Báo cáo sinh học:

Báo cáo sinh học: "Anti-inflammatory effects of nicotine in obesity and ulcerative colitis" pdf

Điện - Điện tử

... mice indicating that the cholinergic anti- inflammatory pathway can modulate the inflammatory response even in established sepsis [ 26] The cholinergic anti- inflammatory pathway In the GI tract, ... a7nAChR is essential in mediating the anti- inflammatory effect of ACh [ 16] The cholinergic anti- inflammatory pathway is a brainto-immune mechanism that regulates inflammatory responses via a7-nAChR-dependent, ... acetylcholine receptor Proc Natl Acad Sci 1999, 96: 57 46- 5751 doi:10.11 86/ 1479-58 76- 9-129 Cite this article as: Lakhan and Kirchgessner: Anti- inflammatory effects of nicotine in obesity and ulcerative...
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báo cáo hóa học:

báo cáo hóa học: " Anti-inflammatory therapy by ibudilast, a phosphodiesterase inhibitor, in demyelination of twitcher, a genetic demyelination model" docx

Hóa học - Dầu khí

... sections on glass slides were incubated serially with mouse anti- MBP or rabbit anti- pi-GST antibody, biotinylated goat anti- mouse or anti- rabbit immunoglobulins (Vector Laboratories), and avidinbiotin ... rabbit polyclonal anti- rat-piform of glutathione-S-transferase (pi-GST) antibody (1:1000; MBL, Nagoya, Japan), rabbit polyclonal anti- cow glial fibrillary acidic protein (GFAP) antibody (prediluted; ... The following primary antibodies were used: phycoerythrin (PE)-conjugated anti- TNFα (1:50; PharMingen, San Diego, CA), mouse monoclonal anti- myelin basic protein (MBP) antibody (1:200; Sternberger...
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báo cáo hóa học:

báo cáo hóa học: " Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice" pot

Hóa học - Dầu khí

... De-2H6 for antigen and effector proteins Antibody Aß1–40 (nM) mFcγRI (µM) mFcγRIIb (µM) mFcγRIII (µM) hC1q (µM) 2H6 De-2H6 1 .6 6.5 20 30 39 67 30 taken from the same location in all animals Quantification ... control antibody (panel A) or anti- Aβ C-terminal antibody (2H6; panel C), or deglycosylated anti- Aβ C-terminal antibody (de-2H6; panel E) Magnification = 40×, scale bar = 50 mm Panel G shows quantification ... control antibody (panel A) or anti- Aβ C-terminal antibody (2H6; panel C), or deglycosylated anti- Aβ C-terminal antibody (de-2H6; panel E) Magnification = 40×, scale bar = 50 µm Panel G shows quantification...
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báo cáo hóa học:

báo cáo hóa học: " Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9" docx

Hóa học - Dầu khí

... 5. 56 3.40 0.851 4.04 2. 26 0.752 [CHEC-9] nM 0.0 10.0 50.0 Vmax μM/min/ml Km r2 2.07 66 .52 981 1.42 40.79 957 0.973 24. 06 970 Vmax nM/min/ng Km μM r2 Ki = 4.02 ± 1. 56 nM Human Plasma sPLA2 Ki = 62 .01 ... disorders.) [6, 7,33] CHEC-9 is a putative sPLA2 inhibitor that has recently been identified as an internal fragment of the survivalpromoting, anti- inflammatory polypeptide DSEP/Dermcidin/PIF [6, 8-12] ... Neuroinflammation 20 06, 3:25 Background Pro -inflammatory enzymes and cytokines are increasingly attractive as therapeutic targets for a variety of inflammatory diseases and for the inflammatory component...
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báo cáo hóa học:

báo cáo hóa học: " Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway" doc

Toán học

... variable roles in microglial proinflammatory gene expression This anti- inflammatory promoting role of PI3K/Akt appeared to be specific to microglia, since astrocyte proinflammatory gene expression ... microglia upregulate key anti- inflammatory cytokines and downregulate proinflammatory cytokines such as IL-1 We provide evidence that the PI3K/Akt pathway plays an anti- inflammatory role in microglia ... IL-1RN (IL-1ra) 6. 4 1.9 IL-10 IL-10RA (IL-10R) 2.4 IL-27 1.8 IL-8 0.3 CXCL1 0.5 Difference in expression (IRF3 minus GFP) 418 1441 4 464 7 76 -708 -4738 2211 364 1145 250 -15409 - 167 Human fetal...
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báo cáo hóa học:

báo cáo hóa học:" Anti-inflammatory effects of nicotine in obesity and ulcerative colitis" potx

Hóa học - Dầu khí

... mice indicating that the cholinergic anti- inflammatory pathway can modulate the inflammatory response even in established sepsis [ 26] The cholinergic anti- inflammatory pathway In the GI tract, ... a7nAChR is essential in mediating the anti- inflammatory effect of ACh [ 16] The cholinergic anti- inflammatory pathway is a brainto-immune mechanism that regulates inflammatory responses via a7-nAChR-dependent, ... acetylcholine receptor Proc Natl Acad Sci 1999, 96: 57 46- 5751 doi:10.11 86/ 1479-58 76- 9-129 Cite this article as: Lakhan and Kirchgessner: Anti- inflammatory effects of nicotine in obesity and ulcerative...
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Báo cáo toán học:

Báo cáo toán học: "Anti-inflammatory new coumarin from the Ammi majus L." pdf

Toán học

... DMSO-d6 as the solvents (25°C) Position DMSO-d6 13 H C H 13 C – – – – C2(C=O) – 162 .5 – 161 .8 C3 6. 29s 113.2 7.95d 117.05 C4 – 152 .6 6.72d 147.3 C5 6. 62d 109.3 5.35d 113.4 C6(OH) 6. 43d 143.7 6. 25d ... powder ( 26 mg; from CH2Cl2–EtOAc 1:1); mp 158– 160 °C; [α]D + 46. 6 (CHCl3) The data from IR (KBr), 1H NMR and 13 C NMR proposed that compound is xanthotoxin [ 16 20]; anal calcd for C12H8O4 % C 66 .64 , ... C6(OH) 6. 43d 143.7 6. 25d 143 .6 C7 – 1 46. 8 – 1 46. 2 C8 6. 82d 104.9 6. 80d 104.2 C9 – 147.5 – 149.7 C10 – 112.5 – 111.3 C11(CH3) 2.45s 19.8 – – C12(OCH3) 3.84s 56. 3 3.79s 56. 1 ...
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báo cáo hóa học:

báo cáo hóa học:" Anti-inflammatory new coumarin from the Ammi majus L." docx

Hóa học - Dầu khí

... DMSO-d6 as the solvents (25°C) Position DMSO-d6 13 H C H 13 C – – – – C2(C=O) – 162 .5 – 161 .8 C3 6. 29s 113.2 7.95d 117.05 C4 – 152 .6 6.72d 147.3 C5 6. 62d 109.3 5.35d 113.4 C6(OH) 6. 43d 143.7 6. 25d ... powder ( 26 mg; from CH2Cl2–EtOAc 1:1); mp 158– 160 °C; [α]D + 46. 6 (CHCl3) The data from IR (KBr), 1H NMR and 13 C NMR proposed that compound is xanthotoxin [ 16 20]; anal calcd for C12H8O4 % C 66 .64 , ... C6(OH) 6. 43d 143.7 6. 25d 143 .6 C7 – 1 46. 8 – 1 46. 2 C8 6. 82d 104.9 6. 80d 104.2 C9 – 147.5 – 149.7 C10 – 112.5 – 111.3 C11(CH3) 2.45s 19.8 – – C12(OCH3) 3.84s 56. 3 3.79s 56. 1 ...
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Báo cáo khoa học:

Báo cáo khoa học: " The Antinociceptive and Anti-inflammatory Effect of Ethylacetate Extracts from Bang-Poong (Radix ledebouriellae) on the Freund’s Adjuvant-Induced Arthritis in Rats" pot

Báo cáo khoa học

... 28 .65 ±3.40 in SDH, 14.20±1.70 in NP, 14.95±1.72 in NECK, and 3.30±0.50 in VENT BPE treatment significantly decreased the number of Fos-positive neurons in SDH (18. 861 .93) and NP (7. 86 0. 86) ... Serum level of IL -6 was 53.54±7.79 pg/ml in sham group (Fig 6) Adjuvant injection and vehicle treated animals showed the significantly increased the serum IL -6 at a level of 161 .44± 15.32 pg/ml ... the treatment of BP in this study suggested that the antinociceptive effect of BP on adjuvantinduced arthritis in rats To investigate the anti- inflammatory effect of genus Radix medical herb, numerous...
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Báo cáo y học:

Báo cáo y học: "Clinical Management of Adult Patients with a History of Nonsteroidal Anti-Inflammatory Drug–Induced Urticaria/ Angioedema: Update" ppt

Báo cáo khoa học

... Clin Immunol 19 96; 98 :67 8– 85 13 Sanchez-Borges M, Capriles-Hulett A Atopy is a risk factor for nonsteroidal anti- inflammatory drug sensitivity Ann Allergy Asthma Immunol 2000;84:101 6 14 Asero R ... challenge with alternative nonsteroidal anti- inflammatory drugs (NSAIDs) and paracetamol in patients intolerant to these agents Drugs 1993; 46 Suppl:253 6 20 Sanchez-Borges M, Capriles-Hulett A, ... nonsteroidal antiinflammatory drugs Ann Allergy 1987;57:113–8 Papa G, Romano A, Del Bono A, et al Floctafenine: a valid alternative in patients with adverse reactions to nonsteroidal anti- inflammatory...
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Báo cáo y học:

Báo cáo y học: " Nonsteroidal Anti-Inflammatory Drug Hypersensitivity in Preschool Children" pot

Báo cáo khoa học

... increased by the use of antipyretic doses of ibuprofen ADR adverse drug reaction; ASA acetylsalicylic acid; NSAID nonsteroidal anti- inflammatory drug 6, 7, 14, 15 13 9, 10, 11, 12 15, 16 17 18 Kidon et ... Hypersensitivity to Nonsteroidal Antiinflammatory Drugs Among Young, Asian, Atopic Children Pediatrics 2005 16 Speer F, Denison TR, Baptist JE Aspirin allergy Ann Allergy 1981; 46: 123 6 17 Lesko SM, Mitchell ... RP Effect of salicylates in urticaria Br Med J 1 967 ;4: 262 –4 36 Wright AL, Minford A Urticaria and hidden salicylates Pediatr Dermatol 1999; 16: 463 –4 37 Botey J, Ibero M, Malet A, et al Aspirin-induced...
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Báo cáo y học:

Báo cáo y học: "The anti-inflammatory effects of levocetirizine - are they clinically relevant or just an interesting additional effect" pptx

Báo cáo khoa học

... all the antihistamines reviewed, followed by fexofenadine and desloratadine respectively [ 16] Anti- inflammatory effects - In vitro There is considerable interest in the effect of anti- inflammatory ... mechanisms underlying the effects of H1-antihistamines have indicated that, in addition to their being a potent antihistamine, levocetirizine exhibits anti- allergic/antiinflammatory effects, some of which ... volunteers Allergy 2001, 56: 50-7 Hair PI, Scott LJ: Levocetirizine: a review of its use in the management of allergic rhinitis and skin allergies Drugs 20 06, 66 (7):973- 96 Dubuske LM: Levocetirizine:...
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Báo cáo y học:

Báo cáo y học: " ncremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" potx

Báo cáo khoa học

... 70.4 ( 16. 7) 67 .1 (14.3) - - 0. 06 Sex (female) 58 (55.8%) 163 (57.4%) 0.95 0 .60 to 1.47 0.78 Smoking 28 ( 26. 9%) 51 (18%) 1. 96 1.15 to 3.37 0.01 Alcohol (glasses/week) 9 .6 (33.2) 6. 2 (8 .6) - - 0.12 ... Difference No of complications (95% CI) 13.8 (13.7 to 13.9) 3 .60 (3. 56 to 3 .64 ) 10.2 Costsa (95% € 115 ,67 6 (114,874 to 1 16, 493) € 165 ,770 ( 160 ,789 to 173,444) € 50,094 CI) aCost of cheapest concomitant ... 9 .6 (33.2) 6. 2 (8 .6) - - 0.12 Heart failure 26 (25.0%) 32 (11.3%) 2 .63 1.48 to 4 .67 0.001 Renal insufficiency 16 (15.4%) 15 (5.3%) 3. 26 1.55 to 6. 86 0.001 Myocardial infarction 20 (19.2%) 32 (11.3%)...
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Báo cáo y học:

Báo cáo y học: "Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug" ppsx

Báo cáo khoa học

... Pharmacol Rev 20 06, 58:488-520 Lugnier C: Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents Pharmacol Ther 20 06, 109: 366 -398 Lim ... arthritis, an IL -6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab Ann Rheum Dis 2007, 66 :1 162 -1 167 32 Hafstrom ... in noninflammatory and inflammatory cells Proc Am Thorac Soc 2004, 1:239-2 46 Stellato C: Post-transcriptional and nongenomic effects of glucocorticoids Proc Am Thorac Soc 2004, 1:255- 263 Tuckermann...
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