4—concrete side face blowout strength of a headed

Side Effects: Death - Confessions of a Pharma-Insider

Ngày tải lên : 04/10/2013, 20:14

... it wants That’s all just part of normal, daily life The activities I refer to are strategically planned and part of the official procedure, just as they are part of a pharmaceutical company’s ... weakness and can maintain its clean image of a pharmaceutical industry, carrying out research in the name of humanity “This trial cannot bring your husband back, no matter how it ends At least, ... Others function as I did and what I did vi Side Effects: Death As a patient, you are always a pawn in the game You are the most important pawn The game is tailormade for you and for your children...

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Tài liệu ime Control of a Three Phase 4 Wire PWM Inverter with Variable DC Link Voltage and Battery Storage for PV Application doc

Ngày tải lên : 19/01/2014, 02:20

... 1, January 1991, pp 62-72 [2] Takao Kawabata, Takeshi Miyashita and Yushin Yamamoto, "Dead Beat Control of threePhase PWM Inverter", IEEE Transactions on Power Electronics, Vol 5, No 1, January ... that it does not affect the output voltage References [1] Takao Kawabata, Takeshi Miyashita and Yushin Yamamoto, "Digital Control of three-Phase Inverter with LC Filter", IEEE Transactions on Power ... controllable dc link volta as indica in the ri age ated ight hand sub b diagram d Figure capacitor v voltage of the output filt with unbalanced load and controlled DC lin ter d o nk vo oltage Figure...

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Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc

Ngày tải lên : 19/02/2014, 16:20

... to any other sequences available in FASTA and BLAST database programs at the DNA Data Bank of Japan Recently, we reported the cloning and sequencing of the gene encoding 4-amino-3-hydroxybenzoate ... 10 Takenaka, S., Asami, T., Orii, C., Murakami, S & Aoki, K (2002) A novel meta-cleavage dioxygenase that cleaves a carboxylgroup-substituted 2-aminophenol: puriﬁcation and characterization of ... speciﬁcity and the cofactor References Hasegawa, Y., Muraki, T., Tokuyama, T., Iwaki, H., Tatsuno, M & Lau, P.C (2000) A novel degradative pathway of 2-nitorobenzoate via 3-hydroxyanthranilate in...

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Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc

Ngày tải lên : 20/02/2014, 11:20

... One approach to increase the duration of PNA binding to DNA is to conjugate it to a DNAalkylating reagent so that the PNA becomes covalently bound to its target sequence To this a DNA alkylating ... synthesis and characterization of a novel mitochondria-targeted alkylating reagent and show that it alkylates DNA in vitro and is taken up by mitochondria However, in spite of its substantial import, ... that the extent of alkylation was proportional to the amount of DNA present and was independent of the size of the DNA fragment (Fig 3A, lane 1) As mtDNA in vivo is negatively supercoiled it was...

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Tài liệu Báo cáo khoa học: The single tryptophan of the PsbQ protein of photosystem II is at the end of a 4-a-helical bundle domain docx

Ngày tải lên : 21/02/2014, 00:20

... determined numerical values of the ratio a/ b, and is the theoretical numerical value of ratio a/ b for a mixture of aromatic amino acids (Tyr and Trp), containing the same molar ratio as the protein ... were ¨ carried out in an Aktapuriﬁer-100 apparatus (Amersham Pharmacia Biotech UK Limited) The native PsbQ protein was ﬁrst passed through a cation-exchange High-Trap SP column (1 mL) (Amersham Biosciences ... than average and their maximum values are around The values for all these parameters obtained for the PsbQ model were quite good and the programs did not mark any as poor or inappropriate Another...

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Tài liệu Báo cáo Y học: Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family potx

Ngày tải lên : 22/02/2014, 04:20

... 5¢-GTGAGAAATGGAGATGCTGC-3¢ 5¢-TGTTCCGGAGAGCCTCCTC-3¢ 5¢-CAACGGAAGCACGCATAGGAGCAC-3¢ 5¢-CACCGCATGCATAACTCTAGCTCCTTCTCTTG-3¢ 5¢-GTAAAACGACGGCCAGT-3¢ Ó FEBS 2002 4-Coumarate:CoA ligase gene family ... 5¢-TBACNCARTCNGCNTAYGTBGARAA-3¢ 5¢-GTTCTAAGCTTTTAAGGCGTCTGAGTGGC-3¢ 5¢-AGTTTCAGGGTCAACAACCCTG-3¢ 5¢-CTCGAATTCATGACAACGGTAGCTGCTTCTC-3¢ 5¢-CTCGGATCCATGGCTGATGATGGAAGCAG-3¢ 5¢-TCAGCGTCACCGTTATCCTC-3¢ ... Km(lM) Relative Vmax (% of coumarate) Relative Vmax/Km (lM)1) Gm4CL1 Cinnamate 4-Coumarate Caﬀeate Ferulate Sinapate 3,4-Dimethoxycinnamate Cinnamate 4-Coumarate Caﬀeate Ferulate Sinapate 3,4-Dimethoxycinnamate...

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Báo cáo khoa học: Puriﬁcation and properties of a new S-adenosyl-Lmethionine:ﬂavonoid 4¢-O-methyltransferase from carnation (Dianthus caryophyllus L.) pot

Ngày tải lên : 08/03/2014, 08:20

... several plants, an accumulation of methylated flavonoids has been explained as a protection against pathogens, predators and ultraviolet radiation [2] A recent investigation concerning the pathogenic ... of molecular mass markers are indicated in kDa F 4¢-OMT activity towards the different assayed substrates, transformation products and kinetic analysis The enzyme became inactive when the assayed ... was a mixture of 0.05 M NaPi buffer, pH 3, and acetonitrile (6 : 1, v/v); separation was performed isocratically, at a flow rate of mLÆmin)1, and the volume of injected samples was 10 lL The amounts...

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Báo cáo khoa học: Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a hemeregulated phosphodiesterase from Escherichia coli pptx

Ngày tải lên : 16/03/2014, 13:20

... La Jolla, CA, USA) with pET2 8a( +)-wild-type Ec DosH as a template and using the following respective 5¢-sense primers: 5¢-gatga gtcgggagACCcagctggagaaaaaag-3¢, 5¢-gatgagtcgggagTTTcag ctggagaaaaaag-3¢, ... Yokota et al Sato A, Sasakura Y, Sugiyama S, Sagami I, Shimizu T, Mizutani Y & Kitagawa T (2002) Stationary and timeresolved resonance Raman spectra of His77 and Met95 mutants of the isolated ... whereas Ala and Asn substitutions at Asp40, an amino-acid residue that interacts via two water molecules with the proximal ligand His77, markedly increased the rate of auto-oxidation [13] (Table...

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Báo cáo khoa học: Odorant binding protein has the biochemical properties of a scavenger for 4-hydroxy-2-nonenal in mammalian nasal mucosa doc

Ngày tải lên : 23/03/2014, 10:20

... be considered as an extracellular counterpart of the chemical inactivation of HNE that occurs intracellularly via GST and other enzymes that 5138 are abundantly expressed in nasal mucosa [22] ... m)1Æcm)1) after dilution in water AMA was from Sigma Aldrich (Milan, Italy) All other reagents, purchased from different companies, were of analytical grade Rabbit serum raised against HNE–protein adducts ... concentration of AMA Competitions between HNE and AMA are shown for porcine (C) and bovine (D) OBP Protein samples were incubated with a ﬁxed saturating amount of AMA and increasing HNE Each point...

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design of reinforced concrete structure volume 1 DR mashhour a ghoneim

Ngày tải lên : 23/03/2014, 20:34

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Báo cáo khoa học: "THE PROCESS OF COMMUNICATION IN FACE TO FACE VS. COMPUTERIZED CONFERENCES; A CONTROL EXPERIMENT USING BALES INTERACTION PROCESS ANALYSIS" pot

Ngày tải lên : 24/03/2014, 01:21

... Groups Reading, Mass; Addison Wesley Bales, Robert F and Edgar F Borgatta 1955 "Size of Group as a Factor in the Interaction Profile." In A. P Hare, E F Borgatta and R F Bales, eds., Small Groups: ... decision reached APyzapIX Analyses of Variance B a l e s C a t e g o r i e s b y Mode a n d P r o b l e m 9Y~h Hested Factorial Arctic I n d i v i d u a l % Data Bales Category - Shows Solidarity ... probably because much of the behavior of this type in a face to face situation is non-verbal, such as smiling in a friendly manner while nodding encouragement Non verbal acts in this category are...

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Báo cáo khoa học: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes potx

Ngày tải lên : 31/03/2014, 07:20

... the 4-kDa peptide N-terminal primer: 5¢-AACCATGGCTAAAGCAGATTGTAATGG TGCATGT-3¢; the 4-kDa peptide C-terminal primer: 5¢-AAGAATTCTTATTATCCAGTTGGATGTATGCA GAA-3¢ The ampliﬁed sequence was cloned ... were ampliﬁed by PCR strategy using the azuki bean and mung bean genomic DNAs as templates and the synthetic primers legF1 (5¢-AGC AGCAGATTGTAATGGTG-3¢) and legR1 (5¢-CAGC ACTTCAGAATCAGAGTC-3¢) ... studies revealed that a small amount of 4-kDa peptide is localized around the plasma membranes and cell walls [9] The subcellular localization of 4-kDa peptide is similar to that of the 43-kDa protein,...

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Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc

Ngày tải lên : 31/03/2014, 09:20

... signiﬁcant hemolytic activity as well as the largest antimicrobial activity, yielded a ½h208 =½h222 even lower than that of native GGN4, as well M M as a larger j½h222 j than that of native ... gray, respectively The direction of view is approximately perpendicular to the helical axis in panels A and B, and is parallel to the helical axis in panels C and D rapid exchange of the Hz amino ... location would be advantageous to facilitate the amphipathic interaction between the peptide and the membrane surface, as the tryptophan side chain is amphiphilic in nature The tryptophan side...

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Báo cáo hóa học: " Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" docx

Ngày tải lên : 18/06/2014, 22:20

... Rejas J, y el grupo para el estudio de la validación al español de la escala LANSS: Adaptación lingüística y validación al español de la escala LANSS (Leeds Assessment of Neuropathic Symptoms and ... by an unrestricted grant from Pfizer Spain The authors wish to thank Francisco González (Hospital de la Princesa, Madrid, Spain), Mar a Madariaga (Hospital de la Princesa, Madrid, Spain) and Carmen ... European Federation of IASP Chapters (EFIC), Istanbul, 2006 References NP: Neuropathic pain; NNP: Non Neuropathic pain; IASP: International Association for Study of Pain; VAS: Visual Analogue Scale;...

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báo cáo hóa học: " Similar promotion of Aβ1-42 fibrillogenesis by native apolipoprotein E ε3 and ε4 isoforms" pptx

Ngày tải lên : 19/06/2014, 22:20

... in late-onset Alzheimer disease Proc Natl Acad Sci USA 1993, 90:9649-9653 Holtzman D, Bales K, Tenkova T, Fagan A, Parsadanian M, Sartorius L, Mackey B, Olney J, McKeel D, Wozniak D, Paul S: Apolipoprotein ... either on a "catalytic" "pathological chaperoning" model of apolipoprotein E action on A , or with a "seeding" model of A folding Detailed biochemical characterization of this native apolipoprotein ... Journal of Neuroinflammation 2004, 1:15 13 14 http://www.jneuroinflammation.com/content/1/1/15 Iwatsubo T, Odaka , Suzuki N, Mizusawa H, Nukina N, Ihara Y: Visualization of A 42(43) and A 40...

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báo cáo hóa học: " 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia" pptx

Ngày tải lên : 19/06/2014, 22:20

... 5'GGAGGAATGGGAGTTGCTGTTGAA-3'; IL-1β, forward 5'-GAGAGACAAGCAACGACAAAATCC-3' and reverse 5'TTCCCATCTTCTTCTTTGGGTATTG-3'; TNFα, forward 5'CTTCTGTCTACTGAACTTCGGGGT-3' and reverse 5'TGGAACTGATGAGAGGGAGCC-3'; and iNOS, ... LPS- and A -induced activation of Pkb/Akt kinase activity, but activates AMP kinase activity, in astrocyteAICAR inhibits LPS-and A -induced activation of Pkb/Akt kinase activity, but activates AMP ... the anti-inflammatory role of AICAR via activation of AMPK in quenching LPS-induced proinflammatory responses by blockade of MAP kinase and IKK α/β-signaling cascades [19] AICAR treatment activated...

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báo cáo hóa học:" Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" pdf

Ngày tải lên : 20/06/2014, 16:20

... Rejas J, y el grupo para el estudio de la validación al español de la escala LANSS: Adaptación lingüística y validación al español de la escala LANSS (Leeds Assessment of Neuropathic Symptoms and ... by an unrestricted grant from Pfizer Spain The authors wish to thank Francisco González (Hospital de la Princesa, Madrid, Spain), Mar a Madariaga (Hospital de la Princesa, Madrid, Spain) and Carmen ... European Federation of IASP Chapters (EFIC), Istanbul, 2006 References NP: Neuropathic pain; NNP: Non Neuropathic pain; IASP: International Association for Study of Pain; VAS: Visual Analogue Scale;...

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báo cáo hóa học:" Quality of life in colon cancer patients with skin side effects: preliminary results from a monocentric cross sectional study" pot

Ngày tải lên : 20/06/2014, 16:20

... DBB, AC and MM presented the study to patients, collected and assembled data BC and MP perform the data analysis and discussed results with other authors ZA and MP drafted the article and all ... all the authors reviewed it and gave final approval of the version to be published Author Details di Oncologia Medica, Fondazione Poliambulanza, Via Bissolati 57, 25124 Brescia, Italy and 2Istituto ... Total sample (n° = 45) Sex Age - levels Age and Male Age and Female Clinical outcome Grade skin toxicity The severity of clinical condition (mainly metastatic colon cancer patients), the impact...

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Báo cáo hóa học: " Research Article Impact of LQI-Based Routing Metrics on the Performance of a One-to-One Routing Protocol for IEEE 802.15.4 Multihop Networks" docx

Ngày tải lên : 21/06/2014, 11:20

... 100%) As the average LQI decreases, the standard deviation of LQI increases, to reach a peak value of 13.8 for an average LQI of 79.1 From this point, as the average LQI decreases further, the standard ... LQI of lost packets [19] 6.2 Variability of the LQI of a Link Figure depicts the standard deviation of the LQI against the average values of LDR (%) EURASIP Journal on Wireless Communications and ... on Advanced Information Networking and Applications Workshops/Symposia (AINAW ’07), vol 1, pp 159–164, Niagara Falls, Canada, May 2007 [16] R Draves, J Padhye, and B Zill, “Routing in multi-radio,...

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báo cáo hóa học:" Research Article Design and Implementation of a Testbed for IEEE 802.15.4 (Zigbee) Performance Measurements" doc

Ngày tải lên : 21/06/2014, 18:20

... for each trial A second Java program (Analyze.java) was developed to analyze the saved files containing the received packets Since the transmitted data is known, this program can easily calculate ... for that particular packet All of these packets are picked up by BaseStation.java listening on the USB port and it saves each consecutive packet in a file for future analysis A new file is created ... running BaseStation.java as a console command Three of the input arguments include: the node ID of the transmitter node that is asked to send the data packets, the number of data packets the transmitter...

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