... from the X-ray structure ofthe C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible An enlargement ofthe region of Ure2p involved inthe interaction ... located within the C-terminal domain of Ure2p that interacts with Ssa1p Because the C-terminal domain of Ure2p is tightly involved inthe assembly ofthe prion into fibrils [25–28] and because Ssa1p ... spanning residues 327–335 upon assembly of Ure2p into fibrils [33] Thus, the binding of Ssa1p inthe vicinity of this stretch interferes with Ure2p assembly into fibrils either because of a change in...
... target of opening 35,000 rooms (excluding Motel 6) in 2012 Ofthe new rooms, 48% were opened inthe Asia-Pacific region, 28% in Europe, 14% in Latin America and 10% in Africa/Middle East The expansion ... over the year and 2.1% inthe fourth quarter Revenue inthe Economy segment rose by 2.1% like-for-like and 3.2% as reported inthe fourth quarter The gains were driven bythe sharp 28.7% increase ... dynamic of existing hotels in Europe Fast organic growth in emerging markets The strategic acquisitions of Mirvac in Australia/New Zealand and of Grupo Posadas’ hotels in Latin America Accor therefore...
... to the ability to increase or decrease the metabolic demand, or to maintain the flow despite the increase or the reduction ofthe systemic blood pressure [5,6] When the MAP exceeds the limits of ... to our hospital complaining of severe headaches since the eighth month of pregnancy, which had worsened inthe last five hours The following information was observed inthe prenatal card: G1P0A0; ... phase, and by fibrosis, fatty infiltration and cell decrease inthe involution phase They are not present at birth, developing during the first months of life, and in 95% of cases they undergo...
... physical health’ is the most influential factor inthe frequency of ecstasy use However, only a minority of users wanted to reduce theuse or discontinue using the drug [14] The association between ... diabetes mellitus, assessing the impact of substances of abuse on the level of acidosis ofthe diabetic ketoacidosis Ofthe 19 patients evaluated, six had used ecstasy Drug users were found to develop ... already tried drugs of abuse is high in secondary schools inthe interior ofthe state of São Paulo; only 0.9% had already consumed ecstasy The average age at the time ofthe first experience...
... physical health’ is the most influential factor inthe frequency of ecstasy use However, only a minority of users wanted to reduce theuse or discontinue using the drug [14] The association between ... diabetes mellitus, assessing the impact of substances of abuse on the level of acidosis ofthe diabetic ketoacidosis Ofthe 19 patients evaluated, six had used ecstasy Drug users were found to develop ... already tried drugs of abuse is high in secondary schools inthe interior ofthe state of São Paulo; only 0.9% had already consumed ecstasy The average age at the time ofthe first experience...
... http://www.harmreductionjournal.com/content/5/1/15 and the patients' acceptance ofthe advice It also evaluated the impact ofthe changes suggested bythe original audit Methods Criteria The following criteria for the adequacy of information ... all health professionals involved inthe care of these patients, including clinic staff, pharmacists, local drug agencies and GPs using verbal and written material or bytheuseof targeted text ... reported that they stored their methadone inthe original container that the pharmacist provided the methadone in All 174 (100%) patients also reported that the container which the pharmacist...
... specifies the bonding of a steel pipe cap to the concrete surface with an epoxy adhesive If the test results not in failure ofthe concrete but in cohesion ofthe epoxy resin adhesive or any failure in ... to the needs of a particular project shall be made bythe Architect/Engineer’s designers and specifiers by reviewing each ofthe items indicated in this specification guide and checklist and then ... title including the year of adoption or revision and are declared to be a part of this Standard Specification ACI 503.3 the same as if fully set forth herein, unless otherwise indicated in the...
... Fig: Brushing unit of a finishing m\c Fig: Singing unit of a finishing m\c Fig: Scew roller of a finishing m\c Fig: Drying cylinder of a finishing m\c Fig: Calendering unit of a finishing m\c Fig: ... line: Finishing Line Fabric Finishing The typical flowchart ofthe denim fabric finishing is as below Loom state fabric ↓ Brushing ↓ Singeing ↓ Brushing ↓ Softening ↓ Correction of skewing ↓ Compressive ... achieved by subjecting the fabric to kind of roller beating action Singeing: The objective of this process is to burn out the protruding fibres from the surface ofthe fabric Only blue side singed...
... up for the failure ofthe 4.3.1 The procedure of Transferring Meaning Through traditional approach by bringing into practice the cognitive process of Metaphors decoding metaphors through the concepts ... ofthe United States from the view of traditional linguists and that of Lakoff From the above findings, the procedure of transferring meaning through metaphors was discussed together with the ... perspectives they may hold inthe innovation ofthe country 25 26 - Inthe realization ofthe metaphorical images derived from the between the source domain and the target one Finally, discovering ICMs,...
... with their sinking velocity -‐ The particles inthe weighting material are also assumed to sink to the sea floor in accordance with the sinking velocity ofthe particles ... keep the cuttings in suspension (in case of e.g stop inthe drilling procedure), lubricate the drill string, work as a cooling agent and keep the pressure inthe ... ofthe vertical distribution ofthe median particle size inthe sediment, some years after completion ofthe drilling program Mixing inthe sediment is caused by...
... students intheuseof subject- verb agreement in English writing Aims ofthe study The study reported in this thesis aims to: - Identify the errors in using SVA in English writing made by high ... make the percentage of errors increase In terms of error causes, the following findings have been obtained: - Most of errors collected belong to intralingual category and there are three main causes ... jeans *is inthe washing machine" In Vietnamese, "quần bò- jeans" is a singular noun And the students seemed to transferthe knowledge of their mother tongue to the target language In their mind,...
... declining inthe late 90’s As the DiffAGE85+ parameter is indefinite in sign results not indicate a pressure to increase the supply of care in homes for the elderly The contribution of each independent ... where the emphasis is on the links between the circumstances of individuals and the receipt of services Given the results ofthe models we formulate predicted changes inthe coverage of in- home ... First, the dependency ofthe elderly population is expected to diminish, pushing the starting-age of domicile and institutional service use upwards Second, increasing the quality of care increases...
... delight inthe beauty of flowers for instance, inthemassof Azaleas which generally stood inthe drawing-room I think he sometimes fused together his admiration ofthe structure of a flower and of ... half-admiring way ofthe ingenuity ofthe leaf of a Sensitive Plant in screwing itself out of a basin of water in which he had tried to fix it One might see the same spirit in his way of speaking of ... been made by an intelligent being, like the hinge of a door by man There seems to be no more design inthe variability of organic beings, and inthe action of natural selection, than inthe course...
... with the top ofthe goblets held first at cm below the opening ofthe tank for minutes and then at 13 cm for minutes and finally at 20 cm below the opening for minute, before plunging them into the ... decreased binding to FT ZP In line with this argumentation, such decreased binding capacity ofthe ZP may reside in changes ofthe structure ofthe ZP that occur during unprotected freezing and/ ... feline ZBA, in contrast to the situation in other species Further studies are needed to explore the causes of our results Competing interests The author(s) declare that they have no competing interests...
... Among the Oldest Old (AHEAD), which is sponsored bythe National Institute on Aging, ofthe National Institutes of Health (NIH), inthe United States The design and sampling approach inthe AHEAD ... maintained as part ofthe medical record and provided to the Medicare insurance carrier on request A recent analysis bythe United States Office ofthe Inspector General (OIG) indicates that the ... two final categories of covariates were theuseof health services, and the supply of chiropractors inthe community There were two measures of self-reported health services use – the number of...
... proportional to the increase ofthe vector inoculum volume The increase inthe number of transduced cells was proportionally less than the increase in inoculum volume, e.g a 10-fold increase in inoculum ... viruses, an "infectious unit" refers to the smallest amount of virus capable of producing an infection in a susceptible cell The titre ofthe original suspension is defined as the number of infectious ... estimate the t(1/2) ofthe vector system used here, we pre-incubated the inoculum for increasing periods of time before applying aliquots to the target cell monolayer By applying the following equations...
... proteins, which are members of two distinct subfamilies, differ inthe DNAbinding specificities of their paired domains by three amino acid residues [32] Therefore, running the EDF pipeline using ... not the result ofthe differences in nucleotide binding specificities between different PAX proteins, but rather the inherent flexibility inthe target preference exhibited by PAX proteins The ... representing the binding site ofthe transcription factor of interest It delivers as output a list of human genes that contain the transcription factor binding site in their promoter region, in a position...