2 mechanisms of action of agents which stimulate sympathetic nervous system
Single channel and whole cell electrophysiological characterizations of l type cav1 2 calcium channel splice variants relevance to cardiac and nervous system functions
... GOALS OF THE STUDY 26 MATERIAL AND METHOD 28 2. 1 CELL CULTURE AND PLASMIDS 29 2. 1.1 Culture of native HEK293 cells 29 2. 1 .2 Plasmids and generation of constructs ... 29 2. 1.3 Sub-cloning of humCaV1 .2 variant 778a into a cardiac backbone structure 31 2. 1.4 Transient transfection of HEK 29 3 cells 32 2.1.4.1 Calcium phosphate method 32 2.1.4 .2 ... 66 3 .2. 2 Exon 1b/1a of humCaV1 .2 influences the current density [pA/pF] 68 3 .2. 2.1 The N-terminal exon 1b increases the current-density of humCaV1 .2 (IV) 70 3 .2. 2 .2 The N-terminal...
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Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx
... to the long term follow-up of both children and adults who receive this form of therapy Journal of Biology 20 06,5 :21 21 .4 Journal of Biology 20 06, Volume 5, Article 21 Duffner Acknowledgements ... chemotherapeutic agents in vitro and in vivo J Biol 20 06, 5 :22 Duffner PK, Cohen ME, Thomas PRM: Late effects of treatment on the intelligence of children with posterior fossa tumors Cancer 1983, 51 :23 3 -23 7 ... 21 .2 Journal of Biology 20 06, Volume 5, Article 21 Duffner reduced for at least weeks following repeated injections of BCNU Overall, the effects of CDDP were more transient...
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Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... >2 Total Total 18 24 25 –34 35–44 45–50 536 ( 92. 4) 44 (7.6) 580 (100) 116 (20 ) 188 ( 32. 4) 24 1 (41.6) 35 (6) 580 (100) 163 (28 .5) 20 5 (35.8) 82 (14.3) 122 (21 .3) 5 72 (100) 27 6 (47.8) 157 (27 ) 129 ... (22 .3) 16 (2. 8) 578 (100) 171 (29 .7) 401 (69.7) (0.5) 575 (100) 81 (20 .6) 28 9 (73.4) 24 (6.1) 394 (100) 120 (30.5) 146 (37.1) 128 ( 32. 5) 394 (100) 122 (21 .1) 455 (78.9) 577 (100) 338 (58 .2) 121 ... (20 .8) 92 (15.8) 30 (5 .2) 581 (100) 26 0 (91.6) 20 (7) (1.4) 28 4 (100) 117 (20 .1) 28 7 (49.4) 160 (27 .5) 17 (3) CI 95% (90–94.4) (5.6–10.1) (16.8 23 .5) (28 .6–36.4) (37.5–45.7) (4 .2 8.3) (24 .8– 32. 4)...
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meskin - phytochemicals - mechanisms of action (taylor, 2005)
... Chem., 49, 19 52 1956, 20 01 22 Passamonti, S., Vrhovsek, U., and Mattivi, F., The interaction of anthocyanins with bilitranslocase, Biochem Biophys Res Commun., 29 6, 631–636, 20 02 23 Prior, R.L., ... Daidzein Tmax (h) Half life (h) Reference 1.4 1.5 1.5 1.5 1.7 3 .2 3.4 1.7 4.4 71 72 72 72 72 0.7 0.5 0.7 4.3 8.4 7.4 11 22 12 10 12 28 8.4 11.8 5.7 5.8 4.7 39 36 39 39 39 36 73 74 75 74 73 75 Measured ... 850–857, 20 02 28 Felgines, C., Texier, O., Besson, C., Fraisse, D., Lamaison, J.L., and Remesy, C., Blackberry anthocyanins are slightly bioavailable in rats, J Nutr., 1 32, 124 9– 125 3, 20 02 29 Igarashi,...
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UPDATE ON MECHANISMS OF HORMONE ACTION – FOCUS ON METABOLISM, GROWTH AND REPRODUCTIONS pptx
... Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration Biochem Biophys Res Commun 28 1 122 0- 122 5 14 Update on Mechanisms of Hormone Action ... Positional cloning of the mouse obese gene and its human homologue Nature 1994; 3 72( 6505): 425 - 32 26 Update on Mechanisms of Hormone Action – Focus on Metabolism, Growth and Reproductions [2] Otero M, ... 20 02; 29 8: 29 7-3 02 [30] Lam, Q L K., Liu, S., Cao, X and Lu, L., Involvement of leptin signaling in the survival and maturation of bone marrow-derived dendritic cells Eur J Immunol 20 06 36( 12) :...
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Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 2) potx
... chemokine herpesvirus type virus receptors (CCR5 and CXCR4) Epstein-Barr Envelope protein CD21 (=CR2) Adenovirus Fiber protein Coxsackie-adenovirus virus receptor (CAR) Coxsackievirus Viral coat ... and histocompatibility major class I antigens Bacterial Pathogens Neisseria spp Pili Membrane cofactor protein (CD46) Pseudomonas Pili and flagella Asialo-GM1 Lipopolysaccharide Cystic aeruginosa...
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Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps
... of 2. 02 × 106 than HA with a MW of 9.5 × 105 [1 02] Similarly, the histology of articular cartilage and synovial tissue was significantly better with an HA of MW = 2. 02 × 106 than with an HA of ... in Canada J Rheumatol 1996, 23 :1579-1585 21 22 23 24 25 Wobig M, Dickhut A, Maier R, Vetter G: Viscosupplementation with hylan G-F 20 : a 26 -week controlled trial of efficacy and safety in the ... et al., 19 92 [68] Nonaka et al., 20 00 [24 ] Nonaka et al., 1999 [69] Decreased levels of PGE2 Lowered IL-1–induced PGE2 production Stimulated cAMP production; decreased levels of PGE2 Reduced expression...
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Báo cáo y học: "Anti-Inflammatory mechanisms of the proteinaseactivated receptor 2-inhibiting peptide in human synovial cells" ppt
... effects of PAR -2 activation and inhibition of COX -2 and MMP-1 expressions in primary OA synovial cells as well as in model cells, which suggested anti-inflammatory mechanisms of the PAR2-IP Trypsin ... types [19 ,20 ] Inhibition of COX -2 antagonized trypsin-induced PAR -2- dependent itching in an animal model [21 ] MMPs mediate cartilage degradation by specifically cleaving matrix proteins [22 ] Studies ... out with μl of template cDNA and 23 μl of PCR buffer containing each primer (0 .2 μM), dNTP (2. 5 mM), and Taq DNA polymerase (1 .25 units) (Takara Bio Inc, Japan) In each PCR, 30 cycles of 30 s at...
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Báo cáo khoa học: " Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities" doc
... Journal 20 09, 6: 124 http://www.virologyj.com/content/6/1/ 124 B Binding activity at 4 92 nm A/Memphis/1/71 (H3N2) ع 2, 3 polymer ً 2, 6 polymer 1.00 0.75 0.50 0 .25 0.00 31.3 62. 5 125 25 0 500 1000 20 00 ... H3N2 A/Aichi /2/ 68 A/Memphis/1/71 96 ± 61 ± 3.13 1.56 82 ± 66 ± H9N2 A/DK/HK/ 92/ 76 21 2 ± 12. 50 34 ± H5N3 A/DK/HK/313/78 A/DK/HK /23 /76 A/DK/HK/677/1 78 ± 124 ± 55 ± 12. 50 3.13 3.13 23 ± 57 ± 50 ... 7.17 0. 12 1.68 103 .20 0. 02 1 .22 77. 72 0. 02 1.69 184.10 0.01 Type of inhibition - Competitive Mixed Competitive Ki(nM) Ki (μg/ml) Kis (μg/ml) - 0.66 - 11.74 190.63 4 32. 60 - Km/Ki Km/Kis - 2. 21 ×...
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mechanisms of type 2 diabetes
... common cause of new cases of blindness among adults 20 -74 years of age • Each year, between 12, 000 to 24 ,000 people lose their sight because of diabetes • During the first two decades of disease, ... 60% of patients with type diabetes have retinopathy Proportion of patients with cardiovascular disease increases with duration of type diabetes 48% 29 % 21 % 24 % 15% < =2 3-5 6-9 10-14 15+ Years T2DM ... duration of type diabetes 67% 62% 53% 42% 31% < =2 3-5 6-9 10-14 15+ Years T2DM Harris,S et al CDA 20 03; Type Diabetes and Associated Complications in Primary Care in Canada: The Impact of Duration of...
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POLITICS IN/ACTION: A COMMUNICATION ANALYSIS OF FACTORS WHICH CULTIVATE CIVIC ENGAGEMENT AMONG YOUTH
... the number of youth between ten and twenty-four years of age will rise to 65 million by 20 20 and could reach as high as 80 million in 20 50 At that point, youth will make up 20 .8 percent of the United ... Delgado (20 02) states, that the “United States Census Bureau estimated that in one decade, 20 00 -20 10, the number of youths thirteen to nineteen years of age will double in size, at a rate of two ... percent by 20 06 and by 20 20, youths (ten to nineteen years) will increase from 34 million in 19 92 to 43 million” (p 12) The growing size of this diverse population coupled with the benefits of civic...
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Molecular mechanisms of mechanosensing at cell cell and cell matrix adhesion 2
... 14 2. 1 The conformational states of protein under force 21 2. 2 Energy landscape of two state model 21 2. 3 Calculated force-extension curve of folded and unfolded i27 23 2. 4 ... unfolded I27 25 2. 5 Calculated force-dependent unfolding and refolding rate of I27 27 2. 6 Calculated force-dependent free energy landscape of I27 as a function of extension ... contour length of ∼ 0.4 nm) 22 Extension (nm) 30 Unfolded Folded 25 20 15 10 0 10 20 30 40 50 Force (pN) Figure 2. 3: Calculated force-extension curve of folded and unfolded i27 2. 1.3 Force dependent...
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Mechanisms of hypoglycemic action of angiotensin peptides in diet induced diabetic mice
... Outline of the experimental strategy 42 2.1 Outline of the experimental protocol of the membrane isolation 54 3.1.1 Effect of DAA-1 on the weight of C57BL/6J mice fed on HFD 62 3.1 .2 Effect of Ang-IV ... sites for SH2 containing PI3K, which is capable of transducing information for GLUT4 translocation Phosphorylation of Tyr895 and Tyr11 72/ 122 2 provide binding motifs for Grb2 and SHP2, respectively ... 73, 25 83 -25 88 Yong-Chiat Wong and Meng-Kwoon Sim, 20 09, Mechanisms of Hypoglycemic Action of Des-Asparate-Angiotensin I in Diet-induced Diabetic Mice, Journal of Diabetes, Vol 1, Issue S1, A230...
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Characterization of CMX 13 and evaluation of efficacy and mechanisms of action in animal model of autoimmunity
... Table 2. 5.3.1 Table 2. 5.3 .2 Chapter Table 3 .2. 1.1 Table 3 .2. 2.1 Table 3 .2. 3.1 Table 3 .2. 4.1 Table 3 .2. 5.1 Table 3 .2. 5 .2 Table 3 .2. 6.1 Chapter Table 4 .2. 1.1 Table 4 .2. 2.1 Table 4 .2. 2 .2 Table 4 .2. 5.1 ... 4 .2. 5 .2 Figure 4 .2. 5.3 Figure 4 .2. 5.4 Figure 4 .2. 5.5 Chapter Figure 5.1.1 Figure 5 .2. 1.1 Figure 5 .2. 1 .2 Figure 5 .2. 1.3 Figure 5 .2. 1.4 Figure 5 .2. 2.1 Figure 5 .2. 2 .2 Figure 5 .2. 3.1 Figure 5 .2. 4.1 ... histograms of Jurkat cells incubated with DMSO, CMX-13 and CH for 24 hrs XXV Figure 4 .2. 2 .2 Figure 4 .2. 2.3 Figure 4 .2. 3.1 Figure 4 .2. 3 .2 Figure 4 .2. 4.1 Figure 4 .2. 4 .2 Figure 4 .2. 4 .2 Figure 4 .2. 5.1...
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Mechanisms of polymer ca2+ interaction and their effects on the characteristics of alginate microspheres and films 2
... 1 .23 88 .23 ± 3.16 29 74.40 ± 1 12. 15 65.71 ± 0.39 CAI 0 .25 59.00 ± 1. 62 86.56 ± 4.67 26 46.34 ± 79.91 73.55 ± 0.48 CAI 0.35 66 .22 ± 2. 21 87 .23 ± 2. 13 22 10.71 ± 22 0.17 76 .24 ± 0. 72 CAI 0 .25 S - 84.51 ... 89 .28 ± 3.55 3141.97 ± 91 .28 67.01 ± 0.89 CAE 0 .25 53.53 ± 1.16 95.89 ± 2. 78 3017.95 ± 127 .73 76. 42 ± 1. 72 CAE 0.35 52. 62 ± 1 .26 99.86 ± 4. 92 2533 .22 ± 163.79 79.48 ± 1.84 CAI 0.15 51.03 ± 1 .23 ... 169. 62 ± 0.98 1 92. 64 ± 3.85 1.04 ± 0.001 14. 02 ± 0.03 17.1 S1 1 72. 28 ± 0.59 197.6 ± 3.85 1.04 ± 0.0 02 14.13 ± 0. 02 22. 9 S2 166 .20 ± 3.17 21 6. 62 ± 4.86 1.05 ± 0.003 13.35 ± 0.01 14.3 S3 24 2.76...
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Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
... JNK-phospho-specific Pan-JNK/SAPK1-43kD BAG-1 Bcl -2 Confidence level 3 3 3 2 1 (-) Under (+)Over + + + + + + + - Fold change 1. 92 2.39 4.96 2. 16 1.85 2. 21 1. 92 2 .29 2. 17 0/+ 1.91 Protein Bid Caspase-6 Caspase-8 ... levels of many proteins at once We selected 40 apoptosis-related proteins and determined Bcl -2, Bid -21 kD, and caspase-8 showed 1. 92- fold, 2. 21-fold, 2. 17-fold, 1.91-fold, 9.40-fold, and 2. 76-fold ... JNK1 &2 protein levels (-fold of control) of JAR over 24 hours of exposure to hypoxia The phosphorylated JNK 1 &2 protein level was measured with Phospho-JNK1 &2( pThr183/pTyr185) ELISA after 12 hours...
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Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp
... kOH·O2 + kOH·H2O2 = kUV.N2 + kOH·O2 + kOH·H2O2 where (7) kUV/H2O2 : pseudo-first order rate constant of pollutants in a VUV/H2O2 system kuv.only VUV direct photolysis N2 VUV direct photolysis system ... 100％, 2 ＝ kH2O/OH / kUV/H2O2 x 100％, θ3 ＝ kuvonly / kUV/H2O2 x 100％, θ4 ＝ kH2O2/OH / kUV/H2O2 x 100％, - 22 - θ1 + 2 + θ3 + θ4 = Journal of Water and Environment Technology, Vol.3, No.1, 20 05 ... C/Co System: 185UV/H2O2 Red141 Initial conc of Red141 =25 mg/l Temp. =25 .0±0.5 Red 141:H2O2=1:80 Rotation rate=750rpm 0.9 0.8 0.7 0.6 System: 185UV/H2O2 Red141 Initial conc of Red141 =25 mg/l Temp. =25 .0±0.5...
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ISOTOPE HYDROGRAPH SEPARATION FOR MODELING OF RUNOFF MECHANISMS OF ATMOSPHERICALLY DERIVED CHEMICAL AND RADIOACTIVE POLLUTANTS
... (5) Na 2 0 24 Oct 21 48 72 Elapsed time (hrs) Oct 22 Oct 23 Oct 24 400 0 24 48 72 Elapsed time (hrs) 24 Oct 21 48 72 Elapsed time (hrs) Oct 22 Oct 23 96 Oct 24 (d) Sb 40 20 96 0 24 48 72 Elapsed ... (a) 10 15 20 25 accumulated precipitation (mm) Oct 21 30 Oct 22 Oct 23 30 Oct 24 (b) 20 10 -38 -40 - 42 -44 -46 -48 -50 - 52 (c) 24 48 72 96 Elapsed time (hrs) since 0000 Oct 21 Fig Record of precipitation ... fraction of new water evaluated for the main part of the runoff (0000 of Oct 22 to 1600 of Oct 23 , 40 h in total) was found to be as shown in Fig 2c The fraction reached its maximum, 0 .21 (21 ...
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Mechanisms of Unstable Nitrite Inhibition of Aerobic Phosphate Uptake
... some of PAOs can that, the inhibitory effect of nitrite will be reduced Hence, the purpose of this study is to examine the effect of anoxic activity of PAOs on reduction of inhibitory effect of ... Cycle Operations of SBRs for Cultivation of the Enriched PAOs - 66 - Journal of Water and Environment Technology, Vol 6, No.1, 20 08 Table - Composition of Synthetic Wastewater Methods of nitrite inhibition ... concentration of nitrite (0 .27 to 4.9mgN.gVSS-1) They were controlled at around 7.0 ±.1 of pH and 20 °C of water temperature Some sludge were tested with several concentration of nitrite so...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose