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1831 nom conserv the lipstick tree family

The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis

The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis

Môi trường

... Thus, the oncogenic potential of loss of Rb is likely to be decided by the expression of each of the Rb family members and the role these family members play in the differentiation of the cell ... Busslinger 1999) The interaction between these proteins is dependent on the large pocket (sub-domains A and B and the C-terminus) of the pRb protein family and a consensus sequence present in the paired-like ... E2F in the S-phase of the cell cycle (Dyson 1998) This might reflect the not yet fully understood specific functions of these proteins at these specific stages of the cell cycle 4.4 pRb Family Mediated...
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The lexus and the olive tree

The lexus and the olive tree

Anh ngữ phổ thông

... bonds and stocks, and put the money either under their mattresses or into the safest U.S bonds they could find So the declines in Brazil and the other emerging markets became the transmission mechanism ... from tree to tree, but seem astonished to find themselves lost in the forest The great strategists of the past kept forests as well as the trees in view They were generalists, and they operated ... understand and then to explain globalization it is useful to think of yourself as an intellectual nomad In the world of the nomad, there is no carefully defined turf That's why the nomads were the ones...
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Tài liệu Andersen’s Fairy Tales THE FIR TREE doc

Tài liệu Andersen’s Fairy Tales THE FIR TREE doc

Kỹ năng nói tiếng Anh

... moment; then they shouted that the whole place re-echoed with their rejoicing; they danced round the Tree, and one present after the other was pulled off ‘What are they about?’ thought the Tree ... happen now!’ And the lights burned down to the very branches, and as they burned down they were put out one after the other, and then the children had permission to plunder the Tree So they fell upon ... the horses dragged them out of the wood Where did they go to? What became of them? In spring, when the swallows and the storks came, the Tree asked them, ‘Don’t you know where they have been taken?...
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Tài liệu THE JUNIPER-TREE -GRIMM''''S FAIRY TALE ppt

Tài liệu THE JUNIPER-TREE -GRIMM''''S FAIRY TALE ppt

Kỹ năng nói tiếng Anh

... rising from the spot, and when these had passed, there stood the little brother, and he took the father and little Marleen by the hand; then they all three rejoiced, and went inside together and ... left, and the millstone round his neck, he flew right away to his father’s house The father, the mother, and little Marleen were having their dinner ’How lighthearted I feel,’ said the father, ‘so ... it she wrapped all the bones from under the table and carried them outside, and all the time she did nothing but weep Then she laid them in the green grass under the juniper- tree, and she had...
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Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc

Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc

Sức khỏe phụ nữ

... for which there is no restriction for use of the method A condition where the advantages of using the method generally outweigh the theoretical or proven risks A condition where the theoretical ... in the UK from 16% in 2002 to 9% in 200411 This still suggests that there is transmission that occurs from individuals taking HIV drug therapy who would therefore know of their infection, there ... when individuals not know their own status Objective and development of these guidelines The aim of these guidelines is to complement the existing guidance on contained in the British HIV Association...
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Tài liệu Báo cáo khoa học: The miRNA-192 ⁄194 cluster regulates the Period gene family and the circadian clock doc

Tài liệu Báo cáo khoa học: The miRNA-192 ⁄194 cluster regulates the Period gene family and the circadian clock doc

Báo cáo khoa học

... indicating the direct suppression of Per1, and by these miRNAs (Fig 3B–D) Together, these data indicate that the miR-192 ⁄ 194 cluster is a potent and direct regulator of the Per gene family Endogenously ... additional targets other than the Per genes that assist in the regulation of the circadian clock However, the alteration of the circadian rhythm seems to be in good agreement with the effects of knockout ... suppresses the synthesis of Per proteins miR-192 ⁄ 194 overexpression alters the circadian rhythm Deregulation of Per genes in mice has been shown to reduce the length of the circadian period As the...
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Tài liệu Báo cáo khoa học: Bioinformatics of the glycoside hydrolase family 57 and identification of catalytic residues in amylopullulanase from Thermococcus hydrothermalis doc

Tài liệu Báo cáo khoa học: Bioinformatics of the glycoside hydrolase family 57 and identification of catalytic residues in amylopullulanase from Thermococcus hydrothermalis doc

Báo cáo khoa học

... either the relationships within a subfamily or the relatedness between the subfamilies (Fig 4) Importantly, the overall integrity of all subfamilies was saved in all trees, including the Pfam -tree, ... on the complete alignment of sequences with the gaps included for the calculation, whereas the second (Fig 4B) is based on the conserved sequence regions As can be seen from the clustering of the ... from Thermococcus hydrothermalis (Q9Y8I8_THEHY), the numbering of the mature enzyme is used [23] The two GH-57 catalytic residues – Glu291 and Asp394 (Q9Y8I8_THEHY) – are highlighted in black The...
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Tài liệu Báo cáo khoa học: Evolutionary relationships of the prolyl oligopeptidase family enzymes docx

Tài liệu Báo cáo khoa học: Evolutionary relationships of the prolyl oligopeptidase family enzymes docx

Báo cáo khoa học

... phylogenetic tree The phylogenetic trees were also constructed using the maximum likelihood method with the program TREE- PUZZLE [16] The TREEVIEW program (http:// taxonomy.zoology.gla.ac.uk/rod/treeview.html) ... respect to the studied enzymes of the POP family, POP seems to be the most conserved enzyme Ten conserved amino acids were found at the active site of the enzyme of each of the studied POP family ... topology [21,22] The DPP II family was used as an outgroup for phylogenetic constructions The two tree- building methods gave essentially the same tree topologies and the neighbour-joining tree with...
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Tài liệu Báo cáo Y học: Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis docx

Tài liệu Báo cáo Y học: Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis docx

Báo cáo khoa học

... and Asp125 In the mutants, the hydrogen bond of the amide nitrogen with the Asp125 side chain is not possible anymore, and the )1 N-acetyl group points away from the C1 atom of the )1 sugar (Fig ... pmol for the Tyr183Phe and Asp125Asn mutants, respectively At these protein concentrations, there is a reasonable linear relationship between the absorbance and the enzyme activity The second ... hevamine, the oxygen atom of the N-acetyl group of the )1 sugar is positioned close to the C1 atom of the )1 sugar, and is hydrogen bonded to Tyr183 Asp125 makes a hydrogen bond to the nitrogen...
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Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx

Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx

Báo cáo khoa học

... and function of the hormonal system We first cloned the genes of the CYP11B family of the guinea pig The 11bhydroxylase of the guinea pig showed higher substrate specificity than the aldosterone ... indicated on the right relation to their abundance in the genome rather than their relative abundance due to differential expression Indeed, this approach lead to the isolation of eight genomic clones ... answer the question how these genes might have evolved we determined the complete genomic structure of both genes As shown in Fig 6, both genes exhibit the typical organization of the family, ...
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Báo cáo khoa học: Structure analysis of the flavoredoxin from Desulfovibrio vulgaris Miyazaki F reveals key residues that discriminate the functions and properties of the flavin reductase family pdf

Báo cáo khoa học: Structure analysis of the flavoredoxin from Desulfovibrio vulgaris Miyazaki F reveals key residues that discriminate the functions and properties of the flavin reductase family pdf

Báo cáo khoa học

... b sheet with the b12 of the other monomer, and towards the C-terminus, the subsequent residues, Phe182Lys186, pass through the a2 vicinity of the other monomer For the FeR dimer, the N-terminal ... Identication of the prosthetic group To identify the prosthetic group bound to the recombinant avoredoxin, UV-visible spectra of the puried holoprotein were recorded (Fig S2) In the visible region, ... important roles The six N-terminal residues (Met1Gly6) are extended in the opposite direction along the b10 of the other monomer, forming an anti-parallel intermolecular b sheet (Fig 2A) The subsequent...
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Báo cáo khoa học: Analysis of the NADH-dependent retinaldehyde reductase activity of amphioxus retinol dehydrogenase enzymes enhances our understanding of the evolution of the retinol dehydrogenase family pot

Báo cáo khoa học: Analysis of the NADH-dependent retinaldehyde reductase activity of amphioxus retinol dehydrogenase enzymes enhances our understanding of the evolution of the retinol dehydrogenase family pot

Báo cáo khoa học

... vertebrate enzymes The most significant difference between the amphioxus and the other retinal reductases was, nevertheless, their preference for the NADH cofactor To our knowledge, these are the first SDR ... families Indeed, the position of the amphioxus enzymes in the phylogenetic tree implied that these families are ancient, pre-dating the emergence of the chordate phylum Discussion The biochemical ... respectively [29] The overall analysis, examining the topology of the phylogenetic tree and the position of each gene inside the cluster, was informative regarding the orthology relationships of the distinct...
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Báo cáo khoa học: Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family pdf

Báo cáo khoa học: Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family pdf

Báo cáo khoa học

... however, there is no report showing the presence of PQRFamide peptides in other vertebrates On the other hand, we recently identified a new member of the RFamide peptide family that has either a ... We therefore characterized the regions in the brain showing the expression of lamprey PQRFamide peptide mRNA using in situ hybridization The expression was localized mainly in the NCP in the ... of the only two extant representative species of the oldest lineage of vertebrates, the Agnatha, which diverged from the main line of vertebrate evolution  450 million years ago, and they therefore...
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Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot

Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot

Báo cáo khoa học

... parallel The numbers at the right represent the pI values of the major bands in e and f, while the numbers at the left are the pI values of standard proteins The arrow at the right represents the ... their molecular mass (kDa) shown at the left The migration position of the Artemia cathepsin L monomer is shown at the right (ACL) Faint bands at 16–18 kDa in the 60 lanes represent CL autodegradation ... proteins in the protein database The Conserved Domain Database of NCBI was screened with the protein coding sequence of clone of CLAP and the Fas I domains in the protein compared with 10 other fasciclin...
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Báo cáo khoa học:

Báo cáo khoa học: "A Compacting the Penn Tree bank Grammar" doc

Báo cáo khoa học

... gives further support to the utility of treebank grammars and to the compaction method For example, compaction methods can be applied within the DOP framework to reduce the number of trees Also, ... extracted from each The staged compaction proceeded as follows: the rule set of the first 10% was compacted, and then the rules for the 4See (Gaizauskas, 1995) for discussion SFor these experiments, ... Conclusions We see the principal results of our work to be the following: * the result showing continued square-root growth in the rule set extracted from the PTB II; • the analysis of the source of...
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Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot

Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot

Báo cáo khoa học

... each other and close to the border that separates the two major parts of the tree Note that the B stearothermophilus maltogenic a-amylase (Bacst) is placed in the ÔCGTase groupÕ of the tree This ... agreement with the complete-sequence tree (Fig 3A) In the group of CGTases produced by the genera Bacillus and Thermoanaerobacter (the large compact clusters in the CGTases group of the trees), the longest ... to the taxonomy of the organisms, while the accompanying catalytic and other domains when analysed in the full length sequence, respect the enzyme specificity Detailed analysis of evolutionary trees...
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The rubber-tree boom in Cambodia: Assessing small landholders’ optimism potx

The rubber-tree boom in Cambodia: Assessing small landholders’ optimism potx

Lâm nghiệp

... in search of land and then add to the increasing rush for land created by economic concessions and companies The question is then what the capacity is for the local economy to absorb or incorporate ... rubber trees, but they express being aware that they will have to learn and appear very confident that they will be able to undertake the work Similarly, they explain that they not know to whom they ... that they will ask employees from concessions or companies who they know; a few said that they had the opportunity to attend trainings; others say that they will learn by doing In the same way, they...
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Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

Báo cáo khoa học

... neuron-specific [8] The APP family of proteins is believed to play important roles in both the peripheral and central nervous systems [6] In the former, they are involved in the formation and correct ... absent in both the APP KO mice and in the cell lysate sample (Fig 1C) The lack of detection of fulllength APP (FLAPP) in APP695-expressing cells is due to the fact that the epitope for the antibody ... the other hand, the  80 kDa APLP1 band was decreased in the BACE1 KO samples ()65.2% ± 3.0%, P < 0.0001) and unchanged in the BACE1 Tg samples ()0.5% ± 7.0%, nonsignificant) (Fig 5B) As was the...
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Báo cáo khoa học:

Báo cáo khoa học: "Parsing preferences with Lexicalized Tree Adjoining Grammars : exploiting the derivation tree" pptx

Báo cáo khoa học

... /',, The Organizerpp The Organizerof Det N N Det 13 -the I~ -the (z-John (z-bucket [3-yesterday ~ -the 13.4he N the demonstration I the bucket [Both derivation trees yield the same derived tree ... are widely accepted, Prefer the derivation tree with the fewer number of nodes Prefer to attach an m -tree low Prefer the derivation tree with the fewer number of 13 -tree nodes Principle takes ... (e.g to the verb) In (el), "of the demonstration" attaches to "organizer" rather than to "suspect", while m (c2) "of the crime" can only attach to the verb Figure shows how principle yields the preferred...
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Báo cáo Y học: Cloning of the manganese lipoxygenase gene reveals homology with the lipoxygenase gene family doc

Báo cáo Y học: Cloning of the manganese lipoxygenase gene reveals homology with the lipoxygenase gene family doc

Báo cáo khoa học

... (including the Fig Organization of the Mn-LOX-Gga gene, Northern and Southern blot analyses (A) The Mn-LOX-Gga gene The open box indicates the protein coding region The solid lines show the 5¢- ... so could the probable LOX of Pseudomonas aeruginosa [39] The homology of Mn-LOX and the LOX gene family included the two a helices of the latter that contain the four Fe(II) ligands These ligands ... sequenced the gene of Mn-LOX of G graminis and the corresponding cDNA Our main finding is that Mn-LOX belongs to the LOX gene family with a unique difference in one of the conserved regions The deduced...
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