Mã sinh viên: B00361 VH - 2015 Mã sinh viên: B00361 VH - 2015 Thang Long University Library - - : - xác khách quan tháng 11 NGU ii trung tâm ã , , tháng 11 iii Thang Long University Library CÁC AIRIAP Asthma Insights and Reality in Asia-Thái Bình BH b BHYT b BN b CLS CGTT CPTT cs CTM c DVYT d GINA Hen) HA h HPQ h ICS LS lâm sàng SABA Short Acting THCS t THPT t VN VP VTTH v XN x XQ X.Quang YT y iv ii iii iv v viii 1.2 Phân tích chi phí 13 13 2.1.1 Tiêu ch 13 13 13 13 13 14 15 15 16 16 16 16 17 17 v Thang Long University Library 18 18 18 19 19 20 20 20 21 21 21 22 3.3.1 S 22 22 3.2.3 B 23 23 24 24 24 24 25 26 26 28 29 29 30 31 32 33 34 vi D 16 18 18 19 19 20 20 21 21 21 11 BHYT 22 12 22 Liên quan 23 23 vii Thang Long University Library 16 16 17 17 18 viii - - Executive Committee) thông báo 24 theo 1,24] t 24,19] Tính toàn - - 24,1], ví Thang Long University Library 13-29-34 t ] n 1,23 [27] 25] t ] N 53,33 6,67 24 Th gian 7,51 chúng 5,31 ngày, BN N cs (2005) BN HPQ sàng c trung bình 10,7 ± 6,9 ngày, t BN - [11] BN - ± 6,2 ngày [10] HPQ HPQ Silly cs 2005 BN HPQ 7,43 ± 6,74 ngày [30] Gibbison Pháp Anh X Wales (2013) ngày [23] 11,71 6,2 ngày g nghiên David H.S BN hen 4,7 ngày [21] Soyiri I.N BN HPQ ngày [32] Lai C.K.W Malaysia; ; 2, [27] ta , BN dài 25 Thang Long University Library 4.2 CÁC 4.2.1 hi trình bày 10, chi phí trung bình cho MDLS 9.014.990 44.465.354 1.729.768 BN có BN 40% Bên HPQ 2005 [11] Xu Bedouch P cs t i Bang HPQ [17] So sánh N 26 007.674, 2.987.453, 3.908.453 1.077.004 [6] [7] Theo y HPQ [9] - [4] (2013) 507.417 [8], th BN theo / So sánh v i c qu nhi u so v i k t qu u tr t c p HPQ t i qu c gia khác th gi i, k t cc khác bi t l n, c v i qu c gia có n n kinh t h th ng y t phát tri n Trong nghiên c u AIRIAP th c hi n t i khu v c Châu Á - Lai C.K.W cs nh n th y chi phí trung bình cho m u tr hen c p có s kh o sát, theo ng l n gi a qu i Trung Qu c 14.324.000 9.832 3.335 [27] i th c Hàn Qu c Dashti R cs (2013) t i Iran l i cho th y u tr t c p HPQ ng 336.580 27 Thang Long University Library u tr / BN [20], th nghiên u so v i s T c Châu Âu, theo nghiên c u c a Bavbek S cs (2011) 294 BN hen thu c 15 trung tâm khác c a Th tr c ti p cho m , chi phí u tr hen c p trung bình 214,9 euro 5.446.640 V [16] khác Serinken M cs (2009) m cho th y , kho ng 836,6 Lira Th 6.830.000 [31] T i Pháp, theo m t nghiên c u c a Sailly J cs (2005) b nh vi n thu c euro [30] hi phí 4.2.2 HPQ, chi phí 51,86% 15,04% óm BN có BHYT BN BHYT HPQ [11] XN BN 28 c th c hi n t i Th chi m 29,32% t ng chi phí y t c c th c hi n t i Th thu u tr tc u tr u tr ch t c p HPQ [16] Trong m t nghiên c a Serinken M (2009), t l chi phí cho chi m 38,5% [31] Nghiên c u t i Pháp c a c ch d ch v y t i b nh , chi phí cho thu m c 13,36%, th m CLS, ch [30] i nhi u nh, chi phí v n chuy n , nghiên c u c a Behbehani NA cs (1999) t i Canada, t ng chi phí cho thu c xét nghi m CLS ch chi m 15,74% chi phí y HPQ [18] Ngay HPQ Dashti R cs (2013) [20] t - 4.3.1 11, chi ph BN heo 3.11 BN 6,19 29 Thang Long University Library , không BHYT BN hay có BN BN [7] [8] ó BHYT V n, 4.3.2 M Theo k chi phí ho , chi phí trung bình trung bình ngày c BN nhóm BN 30 [11] n giúp 4.3.3 T BV 215.557 -21 ngày 243.981 - -13 ngày, 225.216 nhóm > 21 ngày Chi -21 ngày 6.514.303 [11] Tr nh Th Thu Chung (2012) t i khoa Nhi [3] thích cho nh dùng XN CLS chi phí 31 Thang Long University Library , th BN giúp BN, 4.3.4 B Các n Theo n s (2006) BN , chi phí dành cho BN BN [11] nhóm BN kèm (p < 0,01) 32 90 BN Lâm sàng Trung tâm 15 cho cho 9.014.990 5.810.880 1.173.220 704.210 51,86%) BN có BHYT 53,33% nhóm BHYT 42,56% BN có BHYT BHYT Nhóm BN BHYT BN BHYT khác HPQ 33 Thang Long University Library HPQ BN HPQ BHYT BHYT cho BN HPQ HPQ 34 -42 - 75 Tr nh Th Thu Chung (2012) Khóa Công trình NCKH -1998 n Th s b -129 u tr m t ng g p t i b nh vi n huy n oai, Hà N i, 2009 T p chí Y h c th c hành 876 (7), 147 150 -2011 T p chí (860), 3, 77 79 V (804), 1, 51-53 Thang Long University Library nh (2013) Chi phí T p chí (893), 11, 10 10 - - 11 7, 37-39 12 -31 13 Almqvist c., Worm M., Leynaert B (2008) Impact of gender on asthma in childhood and adolescence: a GA2LEN review Allergy 63, 47-57 14 Alzaabi A, Mohammed Alseiari, Mahboub B (2014) Economic burden of asthma in Abu Dhabi: a retrospective study ClinicoEconomics and Outcomes Research 6, 445 450 15 Barnett S.B.L, Nurmagambetov T.A (2011) Costs of asthma in the United States: 2002-2007 J Allergy Clin Immunol 127, 145-52 16 Bavbek S, Mungan D, Türktas H, et al (2011) A cost-of-illness study estimating the direct cost per asthma exacerbation in Turkey Respiratory Medicine 105, 541-548 17 Bedouch P, Marra C.A, FitzGerald J.M (2012) Trends in Asthma-Related Direct Medical Costs from 2002 to 2007 in British Columbia, Canada: A Population ased-Cohort Study PLOS ONE 7, 12, e50949 18 Behbehani NA, Grunfeld A, FitzGerald JM (1999) Healthcare costs associated with acute asthma: A prospective economic analysis Can Respir J 6(6), 521-525 19 Braman SS (2006) The global burden of asthma Chest 130 (suppl 1), 4S 12S 20 Dashti R, Sedighy M, Pourpak Z, et al (2013) Direct Economic Cost of Acute Asthma in Emergency Department Indian J Pediatr 80(8), 708 709 21 David H.S, Daniel C.M, Kenneth A.L, et al (1997) A National Estimate of the Economic Costs of Asthma American Journal of Respiratory and Critical Care Medicine, 156, 3, 787-793 22 Eisenberg J.M, Phamacoeconomics: Schulman K.A, economic Glick evaluation H, Koffer of H (1994) pharmaceuticals Phamacoepidemiology edited by Strom BL, 2nd ed NewYork, Wiley 23 Gibbison B, Griggs K, Mukherjee M, Sheikh A (2013) Ten years of asthma admissions to adult critical care units in England and Wales BMJ Open 3, e003420 24 Global Initiative for asthma Global Strategy for asthma management and prevention, updated 2014, 1-27 25 Holguin F., Bleecker E.R., Busse W.W., et al (2011) Obesity and asthma: An association modified by age of asthma onset J Allergy Clin Immunol 127, 1486-93 26 Ivanova J.I, Bergman R, Birnbaum H.G, et al (2012) Effect of asthma exacerbations on health care costs among asthmatic patients with moderate and severe persistent asthma J Allergy Clin Immunol 129, 1229-35 27 Lai C.K.W, Kim Y-Y, Kuo S-H, et al (2006) Cost of asthma in the AsiaPacific region Eur Respir Rev 15, 98, 10 -16 28 Loftus P.A, Wise S.K (2015) Epidemiology and economic burden of asthma Int Forum Allergy Rhinol 5, S7 S10 29 Mandhane PJ, Greene JM, Cowan JO, Taylor DR, Sears MR (2005) Sex differences in factors associated with childhoodand adolescent-onset wheeze Am J Respir Crit Care Med 172, 45-54 30 Sailly J, Lenne X, Bercez C, et al (2005) Costs of hospitalization for severe acute asthma of patients not treated according to guidelines and recommendations Eur J Health Econom 2(6), 94 101 Thang Long University Library 31 Serinken M, Dursunoglu N, Çimrin A (2009) Therapy costs of adult patients admitting to emergency unit of a university hospital with asthma acute attack Tüberküloz ve Toraks Dergisi 57(2), 198-204 32 Soyiri I.N, Reidpath D.D, Sarran C (2011) Asthma Length of Stay in Hospitals in London 2001 2006: Demographic, Diagnostic and Temporal Factors PLoS ONE 6, 11, e27184 33 Venn A, Lewis S, Cooper M, Hill J, Britton J (1998) Questionnaire study of effect of sex and age on the prevalence of wheeze and asthma in adolescence BMJ 316, 1945-1946 34 Wright AL, Stern DA, Kauffmann F, Martinez FD (2006) Factors Influencing Gender Differences in the Diagnosis and Treatment of Asthma in Pediatric Pulmonology 41, 318-325