PROGRESS I N BRAIN RESEARCH VOLUME 21A CORRELATIVE NEUROSCIENCES PART A: F U N D A M E N T A L MECHANISMS PROGRESS IN BRAIN RESEARCH ADVISORY BOARD W Bargmann M T Chang E De Robertis J C Eccles J D French H H y d h J Ari8ns Kappers S A Sarkisov J P,Schad6 F Schmitt Kiel Shanghai Buenos Aires Canberra Los Angeles Giiteborg Amsterdam Moscow Amsterdam Brookline (Mass.) T Tokizane Tokyo H Waeisch New York J Z Young London PROGRESS I N BRAIN RESEARCH VOLUME 21A CORRELATIVE NEUROSCIENCES PART A : F ~ N ~ A M E N T AMECHANISMS L EDITED BY T TOKIZANE Institute of Brain Research, University of Tokyo, Tokyo (Japan) AND J P SCHADI? Netherlands Central Institute for Brain Research, Anisterdam (The NetherlanrJs) ELSEVIER PUBLISHING COMPANY A M S T E R D A M / LONDON / NEW YORK 1966 E L S E VIE R P U B L I S H I N G C O M P A N Y 335 J A N VAN GALENSTRAAT P.O BOX I, A M S T E R D A M A M E R l C A N E L S E VIE R P U B L I S H I N G C O MPA N Y , I N C VANDE RBIL T AVENUE, N EW YORK N.Y 10017 E L S E VIE R P U B L I S H I N G C O M P A N Y L I M I T E D R I P P L E S I D E C O M M E R C I A L ESTATE, B A R K I N G , ESSEX L IBRARY O F C O N G R E S S CATA LO G C A R D N U M B E R 65-25213 WIT H I L L U S T R A T I O N S A N D TA B LES AL L R I G H T S R ESER V ED T H I S BOOK O R A N Y P A R T T H E R E O F MA Y N O T BE R E P R O D U C E D I N A N Y FO R M , I N C L U D I N G P HOT OS T AT I C O R M I C R O F I L M FO R M , W I T H O U T W R I T T E N P E R M I S S I O N F R O M T H E PU B LI SH ER S PRINTED IN THE NETHERLANDS List of Contributors T ABE,Department of Neuroanatomy, Institute of Higher Nervous Activity, Osaka University Medical School, Osaka (Japan) H AKIMOTO, Department of Neuropsychiatry, Faculty of Medicine, University of Tokyo, Tokyo (Japan) T BAN, Department of Anatomy, Osaka University Medical School, Osaka (Japan) T FURUKAWA, Department of Physiology, Osaka University Medical School, Osaka (Japan) K HAMA, Department of Anatomy, School of Medicine, Hiroshima University, Hiroshima (Japan) T HUKUHARA, Department of Pharmacology, Faculty of Medicine, University of Tokyo, Tokyo (Japan) M ITO,Department of Physiology, Osaka University Medical School, Osaka (Japan) M KATO, Department of Neuropsychiatry, Faculty of Medicine, University of Tokyo, Tokyo (Japan) Y KATSUKI, Department of Physiology, Tokyo Medical and Dental University, Tokyo (Japan) E KAWANA, Department of Neuroanatomy, Institute of Brain Research, Faculty of Medicine, University of Tokyo, Tokyo (Japan) H KUMAGAI, Department of Pharmacology, Faculty of Medicine, University of Tokyo, Tokyo (Japan) M KUROKAWA, Institute of Brain Research, Faculty of Medicine, University of Tokyo, Tokyo (Japan) T KUSAMA, Department of Neuroanatomy, Institute of Brain Research, Faculty of Medicine, University of Tokyo, Tokyo (Japan) H MANNEN, Anatomical-PhysiologicalSection, Institute of the Deaf, Tokyo Medical and Dental University, Tokyo (Japan) K MIYAMOTO, Department of Physiology, Osaka University Medical School, Osaka (Japan) v1 LIST OF C O N T R I B U T O R S K MOTOKAWA, Department of Physiology and Institute of Brain Diseases, Tohoku University School of Medicine, Sendai (Japan) H NAKAHAMA, Department of Physiology, Keio University School of Medicine Tokyo (Japan) H NARUSE, Institute of Brain Research, Faculty of Medicine, University of Tokyo, Tokyo (Japan) S NISHIOKA, Department of Physiology, Keio University School of Medicine, Tokyo (Japan) K OTANI,Department of Anatomy, School of Medicine, Chiba University, Chiba (Japan) T OTSUKA, Department of Physiology, Keio University School of Medicine, Tokyo (Japan) Y SAITO, Department of Neuropsychiatry, Faculty of Medicine, University of Tokyo Tokyo (Japan) F SAKAI, Department of Pharmacology, Faculty of Medicine, University of Tokyo, Tokyo (Japan) A SAKUMA, Department of Pharmacology, Institute of Cardiovascular Diseases, Tokyo Medical and Dental University, Tokyo (Japan) N SHIMIZU,Department of Neuroanatomy, Institute of Higher Nervous Activity, Osaka University Medical School, Osaka (Japan) M SHIMOKOCHI, Department of Physiology, Osaka University Medical School, Osaka (Japan) H SUZUKI,Department of Physiology and Institute of Brain Diseases, Tohoku University School of Medicine, Sendai (Japan) Y TSUKADA, Department of Physiology, Keio University School of Medicine, Tokyo (Japan) N YOSHII,Department of Physiology, Osaka University Medical School, Osaka (Japan) Other volumes in this series: Volume : Brain ~echanisms f Specific und aspecific Mechanisms o Sensory Motor ~ntegrut~on Edited by G Moruzzi, A Fessard and H H Jasper Volume 2: Nerve, Bruin and Memory Models Edited by Norbert Wiener? and J P Schadt Volume 3: The Rhinencephalon and Related Structures Edited by W.Bargmann and J P Schadi: Volume 4: Growth and Maturation of the Brain Edited by D P Purpura and J P Schadk Volume : Lectures on the Diencephalon Edited by W Bargmann and J P Schade Volume 6: Topics in Basic Neurology Edited by W Bargmann and J P Schadt Volume 7: Slow Electrical Processes in the Brain by N A Aladjalova Volume 8: Blogenic Amhes Edited by Harold E Himwich and Williamina A, Himwich Volume 9: The Developing Brain Edited by Williamina A Himwich and Harold E Himwich Volume 10: The Structure and Function ofthe Epiphysis Cerebri Edited by Ariens Kappers and J P Schadi: Volume 11 : Organization of the Spinal Cord Edited hy J C Eccles and J P Schade Volume 12: Physiology of Spinal Neurons Edited by J C Eccles and J P Schadi: Volume 13: Mechanisms of Neural Regeneration Edited b y M Singer and J P Schadt VlII Volume 14: Degeneration Patterns in the Nervous System Edited by M Singer and J P Schad6 Volume 15 : Biology of Neuroglia Edited by E D P De Robertis and R Carrea Volume 16 : Horizons in Neuropsychopharmacology Edited by Williamina A Himwich and J P Schad6 Volume 17: Cybernetics of the Nervous System Edited by Norbert Wiener1 and J P Schadk Volume 18 : Sleep Mechanisms Edited by K Akert, Ch Bally and J P Schadk Volume 19: Experimental Epilepsy by A Kreindler Volume 20: Pharmacology and Physiology of the Reticular Formation Edited by A V Valdman Volume 21B : Correlative Neurosciences Part B: Clinical Studies Edited by T Tokizanc and J P Schad6 Volume 22: Brain Reflexes Edited by E A Asratyan Volume 23 : Sensory Mechanisms Edited by Y Zotterman Volume 24: Carbon Monoxide Poisoning Edited by H.Bow and I McA Ledingham Volume 25: The cerebellum Edited by C A Fox and R S Snider Volume 26 : Developmental Neurology Edited by C G Bernhard Volume 21 : Structure and Function of the Limbic System Edited by W Ross Adey and T.Tokizane x Preface Medical and biological sciences in Japan have a long history As far back as 562 AD medical books were introduced from China, initiating a long period of fruitful medical education and practice An important era of scientific interest in the structure and function of the nervous system began in 19 11 with the publication by Prof Shiro Tashiro on the carbon dioxide production of nerve fibers Prof Genichi Kato announced in 1920 his famous theory of non-decremental nerve conduction and presented all the evidence at the International Physiological Conference in 1926 His research was a major breakthrough in the physiology of single nerve fibers He had a profound influence on the development of physiology in Japan and directing interest toward neurophysiology From that time on the majority of Japanese scientists have been engaged in research in the brain sciences The present volume is the first of a set of two, containing reviews and surveys of brain research in the majot Japanese laboratories and institutes It particularly reflects the progress of Japanese research in the basic and clinical neurological sciences Part A covers important fields such as: neural regulations of autonomic functions, basic mechanisms of vision and hearing, histochemistry and submicroscopy of synapses and dendrites, enzymatic and metabolic parameters of behavior and convulsive states Part B will deal with clinical neurological studies and the relationship of neuroanatomy, neurophysiology and neurochemistry to the clinical sciences It is a rare occasion that one acquires an overall view of the research activities of a large country in such an important field of the medical sciences We trust this volume will provide a means of evaluating the level of brain research in Japan The Editors 350 H A K I M O T O A N D Y S A l T O CREUTZFELDT, AND JUNG, (1961); Neuronal discharge in the cat’s motor cortex during sleep O., R., and arousal The Nature of Sleep G E W Wolstenholme and M, O’Connor, Editors London, Churchill (pp 131-170) DEMPSEY, W., AND MORISON, S., (1942); Production of rhythmically recurrent cortical potentE R ials after localized thalamic stimulation Amer J Physiol., 135,293-300 ECCLES, C., (1957); The Physiology of Nerve Cells Baltimore, Johns Hopkins Press J ENDO, (1962); Effects of specific and non-specific afferent impulses upon neuronal activity of the M., somatosensory cortex in cats Folia psychiat neurol jap., 16,25-61 ENDO,M., ASAI,T., IHARA, , TORII, AND NEGISHI, (1959); Stimulation effects of specific S H., K., and non-specific thalamic nuclei on the unit activity of the somatosensory cortex in the cat Proc Vlllth Ann Meet Jap EEG SOC., (pp 8-11) EVARTS, V.,(1961); Effects of sleep and waking on activity of single units in the unrestrained cat E The Nature of Sleep Ciba Foundation Symposium Series G E W Wolstenholme and M OConnor, Editors London, Churchill (pp 171-182) EVARTS, V.,(1962); Activity of neurons in visual cortex of cat during sleep with low voltage fast E EEG activity J Neurophysiol., 25, 812-816 EVARTS, V., (1964); Temporal patterns of discharge of pyramidal tract neurons during sleep and E waking in the monkey J Neurophysiol., 27, 152-171 HONGO, KUBOTA, AND SHIMAZU, (1963); EEG spindle and depression of gamma motor T., K., H., activity J Neurophysiol., 26, 568-580 HUBEL, H., (1959); Single unit activity in striate cortex of unrestrained cats J Physiol., 147, D 226-238 ITO, M., (1964); On the microelectrode investigations of nerve cells Iyodenshi Seitaikogaku, 2, 19-26 JASPER, H., (1960); Unspecific thalamocortical relations Handbook of Physiology Sect I H Vol 11 J Field, Editor (pp 1307-1321) KLEE, R.,AND OFFENLOCH, (1964); Postsynaptic potentials and spike patterns during augM K., menting responses in cat’s motor cortex Science, 143,488489 LI, C L., (1963); Cortical intracellular synaptic potentials in response to thalamic stimulation J cell comp Physiol., 61, 165-179 C., H LI, C L., CULLEN, AND JASPER, H., (1956); Laminar microelectrode analysis of cortical unspecific recruiting responses and spontaneous rhythms J Neurophysiol., 19, 131-143 Lux,H D., UND KLEE,M R., (1962); Intracelluliire Untersuchungen uber den Einfluss hemmender Potentiale im motorischen Cortex Arch Psychiat Nervenkr., 203, 648-666 MACHNE, CALMA, AND MAGOUN, W., (1955); Unit activity of central cephalic brain stem x., I., H in EEG arousal J Neurophysiol., 18, 547-558 Y., A., H., MAEKAWA, NAKAMURA, HAYASHI, AND AKIMOTO, (1962); Arousal reaction of nonK., specific thalamic neurons Proc Xlth Ann Meet Jap EEG SOC., (pp 60-65) MAEKAWA, NAKAMURA, KUROIWA, , HAYASHI, AND AKIMOTO, (1961); A study of K., Y., S A., H., recruiting response Proc Xth Ann Meet Jap EEG SOC., (pp 4347) MORISON, S.,AND DEMPSEY, W., (1942a); A study of thalamocortical relations Amer J Physiol., R E 135,281-292 MORISON, s.,AND DEMPSEY, W., (1942b); Mechanism of thalamocortical augmentation and R E repetition Amer J Physiol., 138,297-308 G H MORUZZI, , AND MAGOUN, W., (1949); Brain stem reticular formation and activation of the E EG Electroenceph clin Neurophysiol., 1,455-473 Y., K., A,, H., NAKAMURA, MAEKAWA, HAYASHI, AND AKIMOTO, (1961); A new micromanipulator for the deep structures of the brain Proc Xth Ann Meet Jap EEG Soc., (pp 110-1 13) N., T., N., OKUMA, MAEKAWA, KAWAI, MITZUTANI, AND MARUYAMA, (1964); EEG and T., K., the thalamus Advanc neurol Sci., 8, 771-798 V PATTON, D., AND AMASSIAN, E., (1954); Single- and multiple-unit analysis of cortical stage of H pyramidal tract activation J Neurophysiol., 17, 345-363 PHILLIPS, G., (1956); Intracellular records from Betz cells in the cat Quart J exp Physiol., 41, C 58-69 PURPURA, D P., AND COHEN, (1962); Intracehlar recording from thalamic neurons during B., recruiting responses J Neurophysiol., 25, 621-635 PURPURA, P., AND SHOFER, J., (1963); Intracellular recording from thalamic neurons during D R reticulocortical activation J Neurophysiol., 26, 494-505 PURPURA, P., AND SHOFER, J., (1964a); Cortical intracellular potentials during augmenting D R and recruiting responses I Effects of injected hyperpolarizing currents on evoked membrane NEURONAL S Y N C H R O N I Z A T I O N A N D D E S Y N C H R O N I Z A T I O N 351 potential changes J Neurophysiol., 27, 117-132 PURPURA, P., SHOFER, J., AND MUSGRAVE, s., (3964b); Cortical intracellular potentials D R F during augmenting and recruiting responses 11 Patterns of synapticiactivities in pyramidal and non-pyramidal tract neurones J Neurophysiol., 27, 133-1 51 SAITO, (1959); Single cortical unit activity during EEG arousal Psychiai Neurol jap., 61, 1665Y., 1682 SAITO, MAEKAWA, TAKENAKA, AND KASAMATSU, (1957); Single cortical unit activity Y., K., s., A., during EEG arousal Proc Vlih Ann Meet Jap EEG SOC., (pp 95-98) SAITO, NAKAMURA, MAEKAWA, TAKENAKA, KOGA,E., JIMBO, A N D HIRANO, Y., Y., K., S., S., G., ( I 958); Influence of arousal stimulation on photically evoked cortical unit activity Proc VIIth Ann Meet Jap EEG SOC., (pp 39-42) SCHLAG, AND BALVIN, (1964); Sequence of events following synaptic and electrical excitation J., R., of pyramidal neurones of the motor cortex J Neurophysiol., 27, 334-365 SCHLAG, D., AND CHAILLET, (1963); Thalamic mechanisms involved in cortical desynchronizaJ F., tion and recruiting responses Electroenceph clin Neurophysiol., 15, 39-62 SCHLAG, D., AND FAIDHERBE, J J., (1961); Recruiting responses in the brain stem reticular formation Arch ital Biol., 99, 135-162 SPENCER, A., AND BROOKHART,H., (1961a); Electrical patterns of augmenting and recruiting H J waves in depths of sensorimotor cortex of cat J Neurophysiol., 24,2649 SPENCER, A., AND BROOKHART, (1961b); A study of spontaneous spindle waves in sensoriH J H., motor cortex of cat J Neurophysiol., 24,50-65 STARZL, E., T TAYLOR, W., MAGOUN, W., (1951); Ascending conduction in reticular actiC AND H vating system, with special reference to the diencephalon J Neurophysiol., 14, 461477 Towt, A L., PAITON,H D., AND KENNEDY, T., (1963); Properties of the pyramidal system in the T cat Exp Neurol., 8, 220-238 UNO,M., YOSHIDA, AND HIRANO, (1963); Thalamic influences upon membrane potential of M., G., pyramidal tract cells Proc XIlih Ann Meet Jap EEG SOC., (pp 61-62) WHITLOCK, G., D ARDUINI, AND MORUZZI, (1953); Microelectrode analysis of pyramidal A., G., system during transition from sleep to wakefulness J Neurophysiol., 16,414429 YOSHIDA, UNO, M., AND YAJIMA (1965); Monosynaptic activation of PT cells during VL M., K., stimulation In preparation for publication H., A., H., YOSHIDA, YANAGISAWA, SHIMAZU, GIVRE, AND NARABAYASHI, (1964); PhysioM., Y., logical identification of the thalamic nucleus Arch Neurol., 11, 435443 352 Author Index* Abe, T., 197-216 Ades, H W., 72, 313 Adey, W R., 232 Aikawa, S., 182, 184 Aitken, J T., 131, 138, 144, 146 Ajmone Marsan, C., 173, 174, 297 Akiba, H., 295, 312 Akimoto, H., 118,323-351 Altman, J., 315 Amano, T., I , 6, Amassian, V E., 181, 331 Amoroso, E C., 108 Andersen, P., 65, 175, 344 Anderson, J A., 289 Anderson, S A., 87, 184 Arai, Y ,182, 184 Araki, T., 46 Arden, G B., 171, 180 Arduini, A., 323, 324, 345 Arizono, H., 15 Asada, Y.,45, 55, 57, 58, 65 Asai, T., 323 Auer, J., 295 Auerbach, H., 282 Auerbach, V H., 15 Bain, J A., 119 Bainbridge, J G., 108 Balvin, R., 323 Ban, T., 1-43 Barnard, J W., 138, 146 Barr, M L., 145 Barris, R W., 164, 315 Bartelmez, G W., 44, 45, 48, 50 Batini, C., 101 Baxter, D., 132 Beaconsfield, P., 214 Beccari, N., 44 Bell, F R., 108 Beresford, W A., 315 Berl, S., 117, 119, 277 Berlin, L., 181 Berman, A L., 86, 88 Biemond, A., 295 Bishop, P O., 169 Blackstad, T W., 131 Bodechtcl, G., 132 Bodenheirner, T S., 51 Bodian, D., 31, 44.45, 48, 50, 61, 67 Boggen, R H., 295 Boggs, D., 112 Bohner, B., 107 Bok, S T., 138, 146 Bonvallet, M., 101, 102 Borokowsky, T., 280 Bremer, F., 169 Bridger, J T., 131, 138, 144, 146 Brinley, F J., 92 Brodal, A., 132, 136,293,296, 306-308 Brodmann, K., 310 Bromiley, R B., 71 Brookhart, J H., 323, 326 Brooks, V B., 184, 195 Brumm, A,, 117 Bucher, T., 213 Bucher, V M., 315 Buell, M V., 212,213 Butler, R A., 86, 93, 313 Cajal, S Rambn Y., 131, 132 Calma, I., 324, 345, 347, 348 Carman, J B., 310 Carpenter, M B., 306 Carreras, M., 87 Casby, J U., 313 Chaillet F., 348 Chambers, W W., 295, 306 Chang, H T., 325 Chang, M W., 212, 213 Chatschaturian, A., 310 Chen, G., 107 Cheng, C.-S., 198 Churchill, J., 72, 75 Clark, L F., 76 Clark, S L.,297 Clarke, D D., 277 Cohen, B D., 107,324, 339, 342, 344 Cohen, M J 108 Collonnier, M., 168, 175 Coombs, J S., 325 Coplinger, C.B., 112 Cowan, W M., 310 Coxon, R V., 197 Creutzfeldt, O., 323, 345 Crosby, E C., 34 Crossland, J., 124, 126 Italics indicate the pages on wich the paper of the author in these proceedings in printed AUTHOR I N D E X Crouch, R L., 297 Cullen, C., 323 Davis,iH., 71, 76, 84 Davis, P W., 88 86, Dawson,lR M C., 118, 119,268 De Iraldi, A P., 280 Delgado, J M R., 234, 306 Dell, P., 101, 102, 169 De Lorenzo, A J., 131 De Lores Arnaiz, G R., 280 Dempsey, E W., 323 De Robertis, E., 280 Desmedt J E., 73, 75, 80, 83, 87 313 De Valois, R L., 177 Diamond, I T., 86, 93, 313 Diamond, J., 65 Dickens, F., 197 Dirken, M N J., 108 Doran, R., 72, 75 Dudel, J., 59, 66 Dumont, S., 169 Dunlop, C.W., 232 Dusser de Barenne, J G., 300 Eccles, J C., 59, 63-66, 86, 131, 175, 325, 344 Eccles, R M., 59, 175 Elliott, K A C., 127, 197 323 Endo, M., Engstram, H., 72 Ensor, C R., 107 Ertel, R., 289 Erulkar, S D., 84, 86,88,93 Estable, C., 131 Evarts, E V., 324, 345 Faidherbe, J., 342 Fairman, D 300 Fatt, P., 325 Felgenhauer, K., 198, 203 Fernhndez, C ,79 Fex, J., 75, 80 Fifkovh, E., 220 Fish, R., 289 Fleming, L M., 198 Flexner, L B., 210,213 Flock, A,, 64,72 Flood, P R., 131 Foix, Ch., 132 Fox, C A., 138, 146 Frank, K., 59, 63 Friede, R L 198, 210 Frishkopf, L S., 81 Fujita, K., 12, 14 Fujita, M., 2, 5-7 1, Fujita, S., 5, 295 Fujiwara, K., I12 Fukami, Y ,54, 55, 57-59,65 Funatogawa, S., 128 Fuortes, M G F., 59, 63 Furshpan, E J 4649.51-54,57.59,62,67, Furukawa, T., 44-70 Gagel, O., 132 Galambos, R., 64,71, 76, 80, 84, 85 Garol, H W., 304,305,306,310 Gellhorn, E., 102 Gernandt, B E., 108 Gibbs, E L., 98, 102 Gibbs, F A., 98, 102 Gihr, M., 145 Girado, M.,119 Givre, A., 326 Glees, P., 28, 165, 168 Glock, G E 197 Gobbel, W.G., 295 Goldberg, J M.,86, 93 Goldstein, Jr., M.-H., 81 Goswami, M N D., 284 Gottlieb, J S 107 Graven, H., 289 Gray, E G., 131 Greenwood, D D., 86 Gross, N B., 84 Griinthal, E., Guillery, R W ,168, 175 Gurdjian, E S., 24 Gurewitsch, M., 310 Haba, R., 112, 117, 119, 120 Haber, E., 108 Haggar, R A., 145 Hagiwara, S., 251 Hama, K 251-267 Hamburg, M.,210,213 Hamlyn, L H., 131 Hanna, G R., 306 Harlow, H F., 282 Harmon, L D., 79 Hatth, S 280 Hasegawa, A., 1,234 Hashimoto, P H., 198, 199, 202, 203, 213 Hawkins, Jr., J E., 72 Hayashi, A., 325,339 Hebb, C O., 126,127 Hellner, K., 108 Henderson, N., 127 Hendrix, C E., 232 Henneman, E., 304 Hernhndez-Peh, R., 87 Hidaka, T., 16, 17 Hiebel, G., 101 Hilding, D., 75 Hilliard, J., 18 Himwich, H E., 197,213 Hind, J E 86 88, 90 Hirahara, T ,11 Hirai, H., 315, 316 353 251 354 AUTHOR INDEX Hirano, G., 324,325 Hirano, S., 118,268,269,275,277,282 Hirao, T., 101, 128 Huasawa, K., 295 Hirayama, K., 117, 120 fiura, M., 312, 313 Hodes, R , 145 Holaday, D A., 108 Holmes, J E., 232 Hongo, T., 247 Hori, Y., 234 Horie, T., 316 Hotta, S S., 213 Hotta, T ,87 Hubel, D H., 86, 88, 90, 166, 171, 177, 345 Hugelin, A 102 Hughes, J R.,71 Hukuhara, T., 98-111 Hunt, C C., 194 Hurlbert, R B., 117 Iggo, A., 194 Ihara, S., 323 Iida, Y., 280 Imai, Y., 307, 308 Lmaizumi, K., 112 Imamura, G., 100 Ingram, W R.,315 Inoue, K., $ Ishida, S., 14 Ishii, S., 213 Ishii, Y.,198 Ishino, T., 6, Ishizuka, N., 17 Ito, A., 5-7 Ito M., 217-250, 325 Ito, s., 112 Iwakura, I., 1, Iwama, K., 174 Jacobsohn, L., 132 Jasper, H H., 247,297, 323, 325 Jimbo, S., 324 Jimenez-Castellanos, J., 297 Johnson, A R.,174 Jouvet, M., 87 Jowett, M., 214 Jung, R., 345 Kameda, K., 87 Kamrin, A A., 119 Kamrin, R P., 119 Kandel, E R., 92 Kanemitsu, A., 308 310 Kaneki, S., 12, 13 Kanno, Y., 76,78 Kapphan, J I., 212, 213 Kariya, K., 295 Kariya, T., 113, 125, 126 Kasamatsu, A., 333, 345 Kato, E., 174 Kato, J., 14 Kato, M., 112-130 Kato, T., 128 Katsuki, Y., 71-97 Kaufman, S., 213 Kawamura, H., 100 Kawana, E., 292-322 Kawashima, T., 13 Kelley, R., 107 Kemp, E H., 84 Kennedy, T T., 327 Kiang, N.-Y S., 76 Killam, K F., 119 Kimura, R.,72 King, R.B., 303, 306 Kishi, S.,295 Wee, M R., 323,344 Klingenberg, M., I Klingman, W O., 112 Knox, W E., 15,284 Kobayashi, K., 113 Kobayashi, T., 113 Kodaira, A., 277, 295, 307, 312 Koga, E., 324 Kohn, K W., 108 Kojima, H., 109 Kondo, H., Kotake, Y., Kozaki, T., 17 Kraus, W M., 145 Krieg, W J S., 33, 132 Kubo, N., 14 Kubota, K., 347 Kuffler, S W., 59 Kumadaki, N., 109 Kumagai, H., 98-111 Kumamoto, T.,213 Kurachi, K., 7, 8, 17, 21 Kuritani, T.,14 Kurnick, N B., 145 Kuroiwa, S., 324, 331, 333, 339 Kurokawa, M., 112-130 Kurotsu, T., 1-15, 17, 21, 23 Kusama, T., 292-322 Kutsukake, G., 112 Kuypers, H G J M 295, 300, 303, 307 Kwak, R , 173 Lacy, w., 112 LaGrutta, V., 83 Lawn, A N., 108 Legouix, J P., 71 Le Gros Clark, W E 295 Lehninger, A L , 212 Lennox, W G 102 Lennox-Buchthal, M A., 177 AUTHOR INDEX Leontovich, T A., 136 Levick, W R 180 Lhermitte, J., 145 Li, C L., 323, 344 Liles, G W., 295 Lilly, J C., 313 Liu, C N., 295, 306 Livingston, R B., 306 L.loyd, D P C., 170 Long, R G., 169 Lorente de Nb, R., 79, 80, 137 Lowenstein, O., 52, 64 Lowry, H., 212,213 Lowy, K., 84 Layning, Y.,65 Luby, E D., 107 Lundquist, P.-G., 72 Lux, H D., 323 Lyman, F L 282 Mabuchi, M 308 Machiyama, Y., 116, 117, 120, 121, 124, 125 Machne, X.,247, 248 Macy, Jr., J., 181 Maeda, T., 213 Maekawa, K., 324, 331, 339, 345 Maeno, S., 234 Magni, F., 59, 175 Magoun, H W., 136, 324,347, 34R Mandel, P., 280 Mannen, H., 76 78, 131-162 Marburg, O., 132 Mardell, R., 280 Marks, R., 112 Marquis, D G., 163 MarSala, J., 220 Marukashi, J., 194 Maruyama, N., 84, 88 Masai, H., 2, 3, 5-7, 11-13, 17, 23 Masuda, M., Matano, S., 26, 27 Matsui, M., 15, 21 Matsumoto, J., 234 Matsumoto, S., Matsutani, T., 282 McIlwain, H., 197, 213 Mclntyre, A K., 170, 194 McLean, P., 197 McLeod, J G., 169 Meessen, H., 25, 26, I Megawa, A., 21 Megawa, N., 1, 23 Mettler, F A., 295 Mickle, W A., 313 Micklewright, H L., 145 Miki, M., 295 Milner, P., 217, 230 Misaki, Y., 11 Mitsuhashi, Y., 310 355 Miyamoto, K., 217-250 Mizuguchi, K., 194 Momose, T., 10 Monaco, P., 73, 75, 80, 83 Moore, S., 117, 272, 276 Morikawa, N., 198, 199, 210, 213 Morillo, A., 173, 174 Morimoto, A., 3, Morison, R S., 323 Morrel, R M., 92 Moruui, G., 101, 324, 345 Motokawa, K., 163-179 Mountcastle, V B., 86, 88, 184, 188, 193-195, 297, 304, 312 Moushegian, G., 85 Murata, K., 87 Musgrave, F S., 323, 344 Muzuguchi, K., 194 Nachlas, M M., 198 Nagai, M., Nagata, Y., 268, 275, 277 Nakahama, H., 180-196 Nakamura, T., Nakamura Y.,324, 325, 331, 339 Nakanishi, S., 98, 103-105 Nakao, H., 217,232, 233 Nakayama, S., 108 Narabayashi, H., 306, 326 Naruse, H., 112-130 Nasu, T., 113 Nauta, W J H., 33, 313-315 Neff, W D., 86, 93, 313 Negishi, K., 323 Nelson, P G., 86, 93 Ngai, S H., 108 Nicolesco, J., 132 Niimi, K., 295 Nishioka, S., 180-196 Nomoto, M., 77, 80, 85 Nyberg-Hansen, R., 295, 306, 307 Oda, S., Offenlock, K., 344 Ogawa, T., 171 Okada, H., 108 Okada, M., 10, 14,213 Okarnoto, M., k i , T., 31, 34 Okuda, J., 167-172, 175, 176 Olds, J., 217, 230, 231 OL.eary, J L., 164, 166, 168 Olstewski, J., 25, 26 132 Omukai, F., 21, 24, 31 Oonishi, S., 88 Ortmann, R., 198 Osborne, M P 64 Otani, K., 292-322 Otani, T., 46 356 AUTHOR I N D E X Otsuka, N., 49 Otsuka, T., 180-196 Otsuka, Y., 98-100, 103-105 Ozaki, S., 21 Page, H., 197 Palestini, M., 101 Palmer, G., 282 Patton, H D., 327, 331 Pears, A G E , 198 Peele, T L., 295 Peretz, B., 217, 230 Perl, E R., 313 Phillips, C G., 325 Pitts R F., 136 Poggio, G F., 188, 193-195, 312 Polyak, S., 168,295, 315 Pompeiano, O., 308 Potter, A., 132 Potter, D D., 251 Potter, V R., 117 Powell, T P S., 86, 88, 184, 310 Probst, M., 315 Purpura D P., 119, 323, 324, 339, 342, 344 Quastel, J H., 197 214 Rajkovitz, K., 295 Ramon-Moliner, E., 133, 138, 145, 146 Ranson, S W., 136, 315 Rasmussen, G L 30, 137, 313, 314 Reading, H W., 214 RetzlafF, E., 48 Richter, D., 118, 125, 126, 197, 268 Riese, W ,293 Riley, H A., 132 Rinvik, E., 208 Roberts, N R., 212, 213 Robertson, J D., 51 Rose, J E., 71,86, 88,297, 312, 313 Rosenbaum, G., 107 Rosenberg, H., 108 Rossi, G F., 101 Ruben, R J., 80 Rudomin, P., 184, 195 Rupert, A., 71, 84, 85 Russell, D., 107 Rutherford, W., 71 Sailer, S, 233 Saito, Y., 323-351 Saji, Y., 98-100, 103-105, 109 Sakai, A,, 2, 3, 5, 6, 12, 17, 21 Sakai, F., 98-111 Sakuma, A., 98-111 Sakuma, S, 295 Salganicoff, L., 280 Salmoiraghi, G C., 108 Sano, K !18 Satani R., Satani, T ,1 Sawabe, T., 98, 104, 105 Sawyer, C H., 18 Schadk, J P., 145, 155 Scheibel, A B., 132, 136 Scheibel, M E., 132, 136 Scherrer, H., 87 Schlag, J D., 323, 342, 348 Schmidt, R F., 59, 175 Schmitz, H., 117 Schuknecht, H., 72, 75 Schiitz, H., 24 Schwartzkopff, J., 71.84 Sekino, T., 306 Sekula, J., 80 Seligman, A M.,198 Sharpless, S , 247 Shimazu, H., 306, 326, 347 Shimazu, K., 10 Shimazu, T., 15, 16 Shimizu, N., 1, 9,197-216 Shimizu, S.,9, 21 Shimizu, T., 9, 21, 31, 118, 128 Shimokwhi, M., 217-250 Shinoda, H., 13, 16-18, 20, 21 Shinya, G., 1, Shofer, R J., 323, 324, 344 Sholl, D A., 131, 138, 146 Sibley, J A,, 198 Simidu, M., SjUstrand, S., 72 Slayman, C L., 184, 195 Smith, C A., 72 Siiderberg, U., 108, 171, 180 S o w , E D., 198 Spackman, D H., 117,272,276 Spencer, H A., 323 Spencer, W.A., 92 Stage, D E., 51 Stammler, A., 198, 203 Stanl, T E ,248 Stein, W.H., 117, 272, 276 Stern, K., 132 Stewart, W.A., 303, 306 Storm van Leeuwen W., 217 Stumpf, Ch 233 Suga, N., 76,78,80,84,85 Sugimoto, S., 268,269 Sugita, N., 17 Sumi, T., 84 Suter, C., 112 Suzuki, H., 92, 163-179 Swank, R L., 127 Szabo, T., 295 Szenthgothai, J., 163, 295 Tabayashi, C., , 8, 17 Taira, N., 164-172, 175,176 A U T H O R INDEX Takagaki, G., 268, 269,277 Takahashi, R., 125 Takahashi, T., 117 Takakusu, A., 16, 17 Takamura, H., 10, 12 Takano, S., 128 Takeda, M., 6-8 Takenaka, S., 324,345 Takizawa, T., 112 Tamaki, H., 109 Tamura, T., 125, 126 Tanaka, Y., 73 Tane, T., Tanimura, H., 10, 21 Tasaki, I., 67, 71, 76, 80, 194, 251 Taylor, C W., 348 Tazuke, M Thomas, E C., 76, 198 Thulin, C A., 108 Thurlow, W R., 84 Tokizane, T., 100 Torii, K., 21 3, 323 Toru, M., 113 Torvik, A., 295 Towe, A L., 327 Treff, W M., 145 Tsou, K C., 198 Tsukada, Y., 268-291 Tsukahara, Y., 92 Tsutsui, H., 8, 10 Tunturi, A R.,90, 313 Tutikawa, K., 112 Uchiyama, H., 84 Uesugi, M., 295 Uno, M., 325, 327 Utena, H., 128 Uyemura, K., 268, 275,277,280 Valverde, F., 136 Van Bergeyk, W A., 94 Van der Hoeven, Th., 285 Van der Loos, H., 146 Van Gehuchten, A., 137 Van Harreveld, A., 145, 155 Vladimirova, E A., 268 Von Baumgarten, R., 108 Von Bektsy, G., 71, 78, 80, 86 Von Euler, C., 108 Von Frisch, K., 48 Von Helmholtz, H., 71 Von Monakow, C., 315 Voorhoeve, P E., 65 357 Vrba, R., 268 Waelsch, H., 117 119, 277 Waisman, H A., 282 Walberg, F., 132,295, 308 Walker, D G., 198 Wall, D., 28 Wall, P D., 174 Wallenberg, A., 33 Waller, H J., 181 Walzl, E M., 313 Wang, H L., 282 Wang, S C., 108 Ward, J W., 304-306 Watanabe, T., 76, 84, 85, 88 Webster, K E., 310 Weil, A., 145 Wersall, J., 64,66, 72, 75 Whitlock, D G., 313, 314, 323, 324, 345 Whittaker, V P., 123, 127 WidBn, L., 173 Wiesel, T.N., 86, 88, 90, 166 177 Williams, D., 98, 102 Williams, W O., 180 Willis, W D., 59 Wilson, D M., 67 Winkler, C., 132 Woldring, S., 108 Wolff, H G., 102 Woodburne, R.T ,34 Woolley, D W., 285 Woolsey, C N., 86, 300, 301, 303-305, 310, 312 Wyckoff, L B., 282 Y a k , T., 112, 175 Yajima, K., 327 Yamada, M., 15 Yamada, Y., 198, 199,202, 203 Yamaguchi, Y., 217,234 Yamazaki, H., 234 Yamagisawa, N., 306 Yanagisawa, Y., 326 Yokota, T 175 Yokoyama, S , 12 Yoshida, M., 325-327 Yoshii, N 17,217-250 Yuasa, R., 3, 21, Yuasa, S , 115, 128 Zanchetti, A., 101, 323, 326 Zhukova, G P., 136 Zyo, K., 24, 26, 27, 31, 33, 34 58 Subject Index Acetylcholine action on hair cell potential, 76 administration of, 75 chemical transmitter, 73 depolarization of membrane, 76 subcellular distribution, brain, 123, 281 Acetylcholinesterase distribution, 72 N-acetyl-L-aspartic acid mouse brain, 118 Adaptation dark, 166 rapid, brain, 92 Adrenaline local application cerebral cortex, 73 Alanine mouse brain, 118 ALD (aldolase) histochemical detection, 197 postnatal changes, 208 presence i olfactory bulb, 202 n Amino acids interchangeability, 268 metabolic properties, 15 specific neuronal action, 268 Ammon’s horn, Ammonia changes upon neuronal activity, 268 storage properties, 267 Analyzer continuous frequency, 217 Aquaduct cerebral, 32, 34, 36 Area cortical auditory, 86 hypothalamic, 9, 12, 21 lateral hypothalamic, 27 lateral preoptic, 2, 20, 22 medial hypothalamic, 27 medial preoptic, 2,20,22 precentral motor, 87 preoptic, 2, 19, 21,22, 37 septal, 21 somatic sensory, 295,296,297 striate and parastriate, 173 Arginine mouse brain, 118 Arousal phasic frequency spectrum, 241.247 tonic neuronal correlates, 239, 241, 247 Aspartic acid presence in brain, 268 ATPase involvement in neural activity, 197 subcellular distribution, brain, 281 Atropine local application, 73 Auditory cortex lesions, 313 projections, 21 Axon collaterals, 45, 52 M-cell, 46 Basal ganglia endogenous activity, 302 Behavior neural basis, EEG, 217 properties of escape, 230,231 switch-off, 217 waking, sleep and emotional patterns, 17 Blood pressure cerebral control, 98 midbrain activation, rise of, 101 minimizing effect, 101 Bradycardia nervous regulation, Brain stem dendritic arborization, 131-162 localization of learning sites, 220 multipolar and star-shaped neurons, 132 pretrigeminal transection, 101 reticular formation, 87, 102 telestimulation, 245 Bufo vulgaris amino acid content, 269 Bulbus olfactorius content of ALD and SD,202 medial forebrain bundle, 22 rabbit brain, 21 Canisfamiliaris amino acid content, 269 Capillaries glomerular brain tissue, 11 Capsule external, 21 internal, 21 Cavia cobaya amino acid content, 269 cells acinus, pancreas, alveolar, parotis, SUBJECT INDEX epithelial layer, choroid plexus, epithelium, parietal, fundus gland, thyroid follicular, 14 Central nervous system amino acid metabolism, 268 atypical synapses, 252 funneling mechanisms, 86 genesis of malformation, 17 phencyclidine HCL response, strychnine effect, 64 Cerebellum fastigial nucleus, 30 Cerebral cortex auditory integration, 86,92 contralateral visual, 174 inhibition and facilitation, 92 integration of component sounds, 86 neo-, EEG pattern, 98, 109 periamygdaloid, 21, 32 somato-sensory area, 88, 184 visual, 88, 175 0-wave, 241 Chiasm optic, 2,25,28, 32, 33 Cholinesterase subcellular distribution, brain, 281 Clemmys (japonica) amino acid content, 269 Cochlea ascending fibers, 84 basilar membrane, 75 blood barrier, 76 coding, 72 neural response, 75 Colliculus inferior, 25, 32,36, 163 superior, 25, 32, 34, 36, 163 Commissura anterior, 2, 22,25, 33, 35 fornicis, 2, 33 posterior, 25, 28, 35 Conditioned reflex hypothalamic stimulation, 18 Convulsion chemically induced, 1 course of, 1 electrically induced, 112 Corpus callosum connection with cortical areas, 35 dorsal longitudinal fasciculus, 25 fornix system, 33 internal capsule, preoptic area, 35 Curare action of ACh 75 Dasybayus akajei amino acid content, 269 359 Degeneration axonal, myelin pattern, 137 Dehydrogenase gIucose-6-phosphate, 197 lactic, 198 succinic, histochemical detection, 197 Dendrites intrafocal and extrafocal, 132, 133, 136 lateral, 60,62 ventral, 62 Depolarization tonic, pyramidal neuron, 334 Depression postexcitatory, 174 presynaptic component, 174 Deprivation cutaneus input, 180-196 sensory, 194 Diencephalon structural organization, 204 Disinhibition neuronal artifact, 83 DPN-diaphorase interaction with ALD, 212 EEG arousal pattern, 100, 102 artificial respiration, 1 changes after posteromedial hypothalamotomy, 18 correlated with lever-pressing, 223 cortical, 221 desynchronization, 347 effects of ventilation, 98 frequency analysis, 217-250 hippocampal arousal @-wave, 232 phasic arousal pattern, 241 psychological tests, 24 relationship with respiratory center, 99-1 1 switch-off behavior, 217 synchronization, 347 Electrophoresis acetylcholine, 73 Encephalization visual function, 163 EPSP (Excitatory postsynaptic potential) intracellularly produced positive potential, 57 monosynaptic, 327-351 polysynaptic, 327-351 Erythroidine effect on spinal neurons, 75 somatic effects, 76 Excitation antidromic axonal, 53 direct neuronal, 53 orthodromic axonal, 53 ventrobasal thalamic neurons, 180-196 Exophthalmos drug effect, 6,19 360 SUBJECT INDEX Fasciculus ascending and descending fibers, 24 hypothalamo-tegmentalis, 30, longitudinalis dorsalis, 25, 30 longitudinalis medialis, 27-30, 36 pars ventralis, 26 retroflexus, 2,27, 34 36 Forebrain medial bundle (MFB), 22 Fornix rabbit brain, 21 superior, 33 Frequency analysis (EEG) characteristic average, 77 combination with tracer and driver stimulation, 225 histogram, 77 integration, 90 GABA (7-aminobutyric acid) interaction with amino acids, 268 specific neuronal function, 268 subcellular distribution, brain, 281 Gallus domesticus amino acid content, 269 Geniculate body lateral, 36, 163-175.247 medial, electrical stimulation 34, 36, 245, 247 Girella punctata amino acid content, 269 Gland adrenal, duodenal, endocrine, 13 eye and intraorbital, fundus, parietal cells, lymph, production of, submandibular, Globus paltidus supraoptic decussations, 36 Glucose aerobic breakdown, 197 metabolic pathway, 198 metabolism, histochemical detection, 197 6-phosphate dehydrogenase, 197, 199, 210 Glutamic acid presence in brain, 276 Glutamic decarboxylase subcellular distribution, brain, 281 Glutaminase subcellular distribution, brain, 281 Glutamine changes, induced by stimulation, 268 Glutamine synthetase subcellular distribution, brain, 281 Glutathione mouse brain, 118 Glycine mouse brain, 118 Gyrus posterior sigmoid, 297 sigmoid and coronal, 295, 302 Hearing endocochlear, 71 neural mechanism, 71-97 Heterodontus japonicus amino acid content, 269 Hippocampus anterior continuation, 21, 22, 33, 35 periodic changes, 102 Histidine mouse brain, 118 Hydrocephalus experimental production 112 Hypophorin anterior pituitary hormone, Hypophysis extirpation, neurosecretory granules, 10 portal system, Hypothalamus antero-medial, electrical current, 17 electrical stimulation, nystagmus, 30 electroencephalographic changes, 17 gonadotropic stimulus, neurosecretory granules, 10 parasympathetic zone, 17 periventricular stratum, stimulation, Hypoxia arousal pattern of EEG, 102 Inhibition chemical, 52 chemical postsynaptic, 65 collateral, 45, 52, 63 cortical response, 92 dendritic, 59, 60,62 efferent control, 80 W I t h nerve, 65 electrical, 52 model experiment, 61 neural network, 81 neuronal interaction, 85 nonefferent control, 81 presynaptic, 59 receptive properties, 192 remote-dendritic, 63 skin, 184 somatic, 62 spinal presynaptic 63 strychnine, 64 ventrobasal thalamic neurons, 180-196 IPSP (Inhibitory postsynaptic potential) during neuronal synchronization 328-350 receptive field, 192 reversal potential, 56 SUBJECT I N D E X testing with EHP, 54 Isoleucine mouse brain, 118 Junction axo-dendritic, 137 axo-somatic, 137 cholinergic, 65 neuromuscular, 59, 66 LD (lactic dehydrogenase) presence in neurons, 198 Lemniscus medial, 36 Leucine mouse brain, 118 Lobe pyriform, enzyme pattern, 203 Lysine mouse brain, 118 Mamillary body fornix system, 33 supraoptic decussations, 36 Mauthner cells sound receptor organ, 48 synaptic interaction, 44-70 Medulla oblongata, 24, 207 auditory neurons, 84 caudal end, 28 inhibitory system, neocortical activity, 109 periodic discharges, 109 subnucleus reticularis ventralis, 26 Membrane arachnoid, 200 basilar, 75, 78, 79 dendritic, 60 plasma, 25 somatic, 60 synaptic, 51, 251 Membrane potential hair cell, 72 intracellular recording, 86 postsynaptic ending ACh, 76 stimulus sound 93 Meninges cerebral, 200 Mesencephalon, 205 reticular formation, 330-351 Methionine mouse brain, 118 Midbrain auditory neurons, 84 central gray substance, 33 reticular formation, behavior direction, 248 rostral, 33 Neocortex EEG pattern, 98, 109 361 gray matter structure, 199 pentobarbital response, 107 periodic changes, 102 strychnine effect, 107 Nerve fiber ascending, 22, 34 cochlear, 72, 76,79 connection in the SPH-system, 21 degenerated, 22 descending, 24,30 external spinal, 79 hypothalamo-septa1 group, 34 inhibitory and excitatory, 93 internal carotid, mesencephalo-septa1 group, 34 myelination, 44, 79 olivo-cochlear, 80 ovarial, phrenic, 98 radial, 79 saccular, 49 superior cervical ganglia, tractus hypothalamizo-nigralis, 30 vestibular, 79 Neuron auditory, membrane potential, 86 cortical, 323-351 flat-type, 90 inhibitory interaction, 85 model, 61 motor, 45 multi-peak type, 90 multipolar, 132, 133, 139 pre- and postgeniculate, discharge pattern, 163 primary auditory, nature 76 response latency, 77 sharp-peak type, 90 star-shaped, 132, 139 thalamic, 87, 182, 323-351 ventrobasal thalamic, 180-1 96 Neuropil enzyme activity, 199 Nucleus abducens, 22,25,28 ambiguus, 25 anterior olfactory, 22, 25 anterodorsal thalamic, 22, 32 anteromedial thalamic, 22 arcuate, Cajal, 22, 25, 28, 34 caudate, 2.21, 35 centrum medianum, 170 cochlear, 76, 82 cuneatus external 132 Darkschewitsch, 22, 25, 28 dorsal premamilfary, dorsomedial hypothalamic, 2, 21, 25, 26 Edinger-Westphal, 22, 25 entopeduncular, 28, 36 362 S U B J E C T INDEX facialis, 25 Gudden, 22,25 intercalatus, 26 interpeduncular, 25,27, 32, 33, 36 lateral habenular, 22, 25 hypothalamic, 2, 3, 6, 13, 15, 22, 28, 36 mamillary, 1, 2, 21, 22, 25, 27, 33 septal, 22, 33, 35 vestibular, 25, 28 locus incertus, 25 medial central, 25 geniculate, 170 habenular, 22 hypothalamic, 25 mamillary, 1, 2, 21, 22, 27, 33 septal, 22, 33, 35 vestibular, 25, 28 mediodorsal thalamic, 22 oculomotor, 22,25,27, 28, 36 olivar inferior, 136 olivar superior, 84, 133 parataenial, 22, 32 paraventricular hypothalamic, 2, 22 posterior hypothalamic, 2, 21 paraventricular, 25 premamillary, 21 preopticus magnocellular, 20 prepositus hypoglossal, 25, 26, 28 pretectal, 22 septohippocampal, 22, 33, 35 subthalamic, 2, 36 superior vestibular, 25, 28 suprachiasmatic, supragenualis, 25.29 supramamillary, 2,25 supraoptic, 2, 36 trigeminal, 30 trochlear, 22, 25 27, 28, 36 ventral premamillary, ventromedial hypothalamic, 2, 4.25 Nystagmus recording technique, 30 Parapristipoma trilineatum amino acid content, 269 Pathway (tract) auditory, 84 corticofugal, 87 hypothalamo-cerebello-vestibular,30 sensory, 84 somato-sensory, 84,86 visual, 84, 86 Pattern arousal, 102 EEG, artificial respiration, 101 response, colored lights, 175 Peduncle cerebral, 2, 21,27, 34 mamillary, 27, 34 Pentobarbital effect on neocortex, 107 method of application, 180 Perception brightness, 163 sensory pattern, 172 sound mechanism, 48 Phencyclidine HCI effect on cerebral cortex, 107 Phenylalanine mouse brain, 118 Phosphoethanolamine mouse brain, 118 Phosphor lipid content, presence in cholesterol, Plexus choroid, 5, 200 epithelial layer cells, 5, Pons periodic discharges, 109 structural organization, 205 Potential ACh, depolarization of membrane, 76 antidromic action, 45 cochlear microphonic, 72 excitatory postsynaptic (see EPSP) extracellular, 45,46, 52 inhibitory postsynaptic (see IPSP) intracellular, 46 negative, 45, 46 postsynaptic, 93 resting, 56 reversal, 56 Procaine cortical application, 181 Proline, mouse brain, 118 Putamen rabbit brain, 21 Rattus norvegicus albus amino acid content, 269 Reflex conditioned, hypothalamic stimulation, 18 feeding, 36 olfactory, 36 orienting, 235 parasympathetic conditioned, 19 sympathetic conditioned, 19 Respiratory center relationship with EEG changes, 98-1 11 Response arousal (EEG), 102 augmenting, 323-348 cortical, colored lights, 175 excitatory, 48-52 extracellular orthodromic, 57 facilitation cortex, 92 SUBJECT INDEX inhibitory, 52-65, 92 specific PT cells, 335 Reticular formation ascending impulses, 101 bulbar, 170 dendritic arborization, 144 mescncephalic, 170, 33C335 midbrain, dorso-medial part, 220 structural organization, 102 Rhinencephalon structural properties, 202 Synapse axo-axonal, 45, 131 dendro-dendritic, 131, 147 dendro-somatic, 131, 147 electrical, 49 excitatory, electrical, 44,131, 144 geniculate, 164 inhibitory, electrical, 44,131, 144 ordinary, chemical, 50 somato-somatic, 131 transmission, 44, 50 Synaptic delay, 68 Synaptic interaction Mauthner cell, 44-70 System septo-preoptico-hypothalamic(SPH), 21 Seizure amino acid changes, 119 convulsive, in ep mouse, 12-1 15 Self-stimulation response in rat, 230 Sepia esculenta Taurine amino acid content, 269 mouse brain, 118 Septum Thalamus pellucidum, commissural fibers, 32 auditory neurons, 84 precommissural, 21 22, 33, 35 reticular formation, 335, 336 segmental, 251 Tractus Sphaeroides auditory, 82, 84, 86 amino acid content, 269 corticothalamic, 269 Spinal cord hypothalamico-nigralis, 27, 30 anterior funiculus, 28 hypothalamico-tegmentalis, 30 27, shock, conditioning stimulus, 57 hypothalamicus periventricularis, structural aspects, teleosts, 44 hypothalamico-hypophysial, Stimulation lateral olfactory, 2, 22, 32, 35 electrical, medial geniculate body, 245 mamillotegmentalis lateralis, 27 medial hypothalamic, medialis, 27 ventromedial hypothalamic, 11 mamillothalamicus, 2, 27, 32, 36 visual and somatic cortex, 87 optic electric test stimulus, 164 Stratum supraliminal stimulus, 2, 170, 269 hypothalamic periventricular, 1, 2, 21, 22, 25, pyramidal, 27, 36 27, 37 tegmento-hypothalamicus, 27 preoptic periventricular 2, 20, 21, 22 tegmento-mamillaris lateralis, 27 Stria medialis, 27 longitudinalis lateralis, 22, 35 tegmentopeduncularis, 27 longitudinalis medialis, 22, 35 vestibulospinalis, 28 medullaris, 2, 22, 33 Transaminase terminalis, 2, 33 effect of tyrosine and alanine, 16 Strychnine Tuberculum olfactorium antagonistic action, 73 enzyme pattern, pyriform lobe, 203 collateral inhibition, 64 lateral preoptic area, 35 crossed and uncrossed efferents, 73 medial forebrain bundle, 30, 35 inhibitory effect, 75, 83 D-Tubocurarine mechanism of action, 65, 67 decrease of response, 75 neocortex, 107 suppressive effect, 76 Valine Substance mouse brain, 118 central gray, 22, 27, 36 Ventricle Substantia nigra lateral, 35 mamillary peduncle, 27, 34 third, 36 supraoptic decussations, 36 Succinic dehydrogenase Xesurus scalpruin subcellular distribution, brain, 281 amino acid content, 269 363 This Page Intentionally Left Blank ... hypothalamic periventricular stratum (a- parasympathetic zone) and the lateral preoptic area to the lateral hypothalamic area (c-parasympathetic zone), and they all react parasympathetically The... medial preoptic area is a continuation of the medial hypothalamic area (b-sympathetic zone), and the lateral preoptic area is a continuation of the lateral hypothalamic area (c-parasympathetic... layers, (2) area symparhica B or area B consisting of the medial preoptic area and the medial hypothalamic area, and (3) area parasympathica C or area C consisting of the septal region, the lateral