[...]... Plates Structure of the OmpF porin View of the monomer from the side (left) and view of the trimer from the top The loop inside the opening narrows the channel H Nikaido 2003, Microbiol Mol Biol Rev 67, 593±556; Fig 2 Fig 1.2 Dynamics of the Bacterial Chromosome Structure and Function W Schumann Copyright g 2006 Wiley-VCH Verlag GmbH & Co KGaA ISBN 3-5 2 7-3 049 6-7 XVI Color Plates Shuttle model for TonB-dependent... bag of proteins While most proteins may be dispersed throughout the cytoplasm, some seem to Dynamics of the Bacterial Chromosome Structure and Function W Schumann Copyright g 2006 Wiley-VCH Verlag GmbH & Co KGaA ISBN 3-5 2 7-3 049 6-7 2 1 Structure of the Bacterial Cell have specific localizations One example is the B subtilis replisome which is present throughout replication of the chromosome within the. .. throughout the cell cycle, compacting at the division plane in predivisional cells, remaining there until division is complete and then expanding to fill the cell MreB has a role in the maintenance of the cell width and plays a role in chromosome segregation, whereas Mbl is involved in the maintenance of the long axis of the cell Depletion of either MreB or Mbl causes aberrant partitioning of the origins of. .. genomes to the various facets of the regulation of gene expression, a field that even in bacteria includes mechan,, ,, ,, ,, ,, Dynamics of the Bacterial Chromosome Structure and Function W Schumann Copyright g 2006 Wiley-VCH Verlag GmbH & Co KGaA ISBN 3-5 2 7-3 049 6-7 XII Foreword isms of not only transcriptional initiation but also transcriptional elongation and termination and regulation at the posttranscriptional,... R1 forms F-actin-like cables that actively move plasmid DNA In 2001, the three-dimensional structure of MreB of T maritima was solved and revealed that it is congruent with that of eukaryotic actins Later, the structure of a plasmid-encoded ParM protein was solved and shown to be very similar to that of actin and MreB Both proteins and several others, such as Mbl of B subtilis, now belong to the MreB... compounds and nutrients within the cytoplasm and to secrete waste products Structure and Composition of the Cytoplasmic Membrane The cytoplasmic membrane consists of equal amounts of phospholipid and protein It contains 65±75% of the cellular phospholipids and 6±9% of the cellular protein The phospholipids consist of a hydrophobic part (fatty acids) and a hydrophilic part (glycerol), where the glycerol... side chains exposed on the inner surface of the apical domain (B) Next, each equatorial domain of the upper ring binds one molecule of ATP with positive cooperativity (C) This in turn triggers binding of a GroES ring to the upper ring causing an upward movement of the apical domain, retraction of the hydrophobic side-chains and release of the substrate protein into the cavity of the upper GroEL ring... movements and attachment to cell surfaces, respectively We will present an overview of the composition and function of these different compartments For details, classic microbiology textbooks should be consulted 1.1 The Cytoplasm Compartment First of all, the cytoplasm contains all the different types of nucleic acids: the chromosome( s) and quite often one or more plasmids and the arsenal of RNAs (mRNA,... textbook by other experts on the molecular microbiology of Archaea or eukaryotic microorganisms) have been addressed in a very authentic, comprehensive manner and have been illustrated by a lot of impressive and useful figures This book covers the most essential chapters in molecular microbiology, starting with the structure of the bacterial cell via the organization of bacterial chromosomes to the bacterial. .. entity The unexpected finding that, even in the best analyzed model organisms such as Escherichia coli, one-third of all genes codes for proteins with still unknown functions emphasizes ,, the challenge and indicates that many pages of the bible of life are still empty There is a comprehensive literature on the entire field of molecular microbiology, from the structure, flexibility and stability of bacterial . Schumann Dynamics of the Bacterial Chromosome Dynamics of the Bacterial Chromosome. Structure and Function. W. Schumann Copyright g 2006 Wiley-VCH Verlag GmbH & Co. KGaA ISBN 3-5 2 7-3 049 6-7 Related. Co. KGaA ISBN 3-5 2 7-3 049 6-7 Fig. 1.2 Structure of the OmpF porin. View of the monomer from the side (left) and view of the trimer from the top. The loop inside the opening narrows the channel stability of bacterial genomes to the various facets of the regulation of gene expression, a field that even in bacteria includes mechan- XI Dynamics of the Bacterial Chromosome. Structure and Function.