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Front cover
Preface
Editors
Contributors
Table of Contents
Part I
Cellular and Biochemical Issues
1
Human Skin-Equivalent Models of Epidermal Wound Healing: Tissue Fabrication and Biological Implications
1.1 Introduction
1.2 Morphologic Aspects of the Response of Wounded Skin Equivalents
1.3 Proliferative Response to Skin-Equivalent Wounding
1.4 Keratinocyte Migration in Response to Wounding of Skin Equivalents
1.5 Growth Factor Responsiveness and Synthesis in Wounded Skin Equivalents
1.6 Protease Activation in Wounded Skin Equivalents
1.7 Patterns of Keratinocyte Differentiation in Wounded Skin Equivalents
1.8 Summary
1.9 Fabrication of Skin-Equivalent Wound Healing Model
References
2
Epidermal Repair and the Chronic Wound
2.1 Introduction: Important Differences between Acute and Chronic Wounds
2.2 Keratinocyte Function and Wound Healing
2.3 Keratins as Markers of Epidermal Physiology and Wound Healing
2.4 Growth Factors/Cytokines as Regulators of Wound Healing
2.4.1 Interleukin-1 (IL-1)
2.4.2 Tumor Necrosis Factor a (TNFa)
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