Skeletal Miliary a Mycobacterium CSF protein and low CSF glucose TST positive in approximately 30% AFB cultures positive in 20–30% Most commonly spondylitis CXR abnormal in 50% (particularly of the MRI is the best diagnostic thoracolumbar spine), modality arthritis, and TSTs positive in most osteomyelitis AFB cultures of bone positive in up to 75% Fever, hepatomegaly, CXR with diffuse granular splenomegaly, failure to pattern, sometimes with thrive Meningitis is seen superimposed focal in up to 20% of cases of airspace disease miliary TB TST is very insensitive AFB cultures positive in up to 50% tuberculosis also can affect the genitourinary tract, peritoneum, skin, and middle ear CXR, chest radiograph; TST, tuberculin skin test; AFB, acid-fast bacilli; CT, computed tomography; CSF, cerebrospinal fluid