... ofallergy to drugs, e.g. metabolism, combination withprotein, fatal anaphylaxis (see p. 1 43). Treatment. Remove the cause; use cooling appli-cations and antipruritics; use a histamine ... thedrug is withdrawn. Some drugs, notably NSAIDs,induce a 'pseudoporphyria', clinically resemblingporphyria cutanea tarda and presenting with skinfragility, blisters, ... increased risk of adversereactions, which are often severe.Though drugs may change, the clinical problemsremain depressingly the same: a patient develops arash; he is taking...