... preponderance of Th1 type of cytokines, of Th2 type, increase of both, decrease of Th1, but not increase of Th2 etc.Moreover, the response seems to vary betweenperipheral blood and site of lesion; ... as in vitro correlate of protective immunity.A clear picture of the network of immune responsesto this pathogen, as well as an understanding of theeffector functions of these components, is ... demonstrate mycobacterial killing inpresence of IFN-γ, TNF-α and a cocktail of otherstimulants26.There is lack of an experimental systemin which the killing of M. tuberculosis bymacrophages can...