... phase progression is regulated by G1 cyclinand cyclin-dependent kinases (cdks). Cdk4 or cdk6 is associated with D-type cyclins while cdk2 binds to cyclin Eor cyclin A to become an independent and ... phosphorylated by cyclin A/cdk2, cyclin E/cdk2,cyclin A/cdk3 or cyclin E/cdk3 which is produced in the baculoviral systemWe initially tested a hypothesis that p70ik3-1might be aregulatory cyclin for ... wild-type cdk3, notcdk3 dn, were expressed, supporting the theory that cyclin/cdk3 actually phosphorylates ik3-1.P70ik3-1 is phosphorylated by either cyclin A/cdk3 orcyclin E/cdk3 in vivoFurthermore,...