... Binding of the volatile general anesthetics halothaneand isoflurane to a mammalian b-barrel proteinJonas S. Johansson1,2,4, Gavin A. Manderson1, Roberto Ramoni5, Stefano Grolli5and Roderic ... the lipocalin familythat features a large b-barrel internal cavity (515 ± 30 A ˚3) lined predomin-antly by aromatic and aliphatic residues. Halothane binding to the b-barrelcavity was determined ... Pennsylvania, Philadelphia, PA, USA4 Johnson Research Foundation, University of Pennsylvania, Philadelphia, PA, USA5 Dipartimento di Produzioni Animali, Biotecnologie Veterinarie, Qualita`e...