Báo cáo y học: "Management of HBV Infection in Liver Transplantation Patients"
Báo cáo y học: "Management of HBV Infection in Liver Transplantation Patients"
... contributing to the efficacy of combination LAM and HBIG remain poorly defined. Postulated mechanisms include the synergy of: 1) LAM reducing HBV replication and altering synthesis of HBsAg necessary ... 3. HBV Reinfection of Allografts Two mechanisms have been implicated in allograft reinfection: 1) rapid reinfection by HBV in the circulation of the recipient and/or 2) reinfection from HBV ... advances in the management of HBV- infected recipients of OLT during the past 15 years have steadily reduced the rate of reinfection, resulting in improved outcomes. Initially, long-term use of hepatitis...
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Báo cáo y học: "Management of HCV Infection and Liver Transplantation"
... tolerability necessitating frequent dose adjustment and the inability to achieve optimal dosing. Approximately 30% of patients will discontinue therapy. Often the only way of maintaining Int. J. ... is Professor of Medicine at Mount Sinai School of Medicine New York and Associate Director of the Division of Liver Diseases. He has a major interest in the management of viral hepatitis in organ ... described an SVR of 34% in genotype 1patients treated a mean of 3.4 months following OLT suggesting a role for therapy early in the course of HCV. Importantly a predictor of interferon response...
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Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... chiropracticeducational institution offering a training program coor-dinated by a medical physician. However, this is in itsinfancy and much needs to be worked out. This does indi-cate a growing level of interest in ... provision ofportal -of- entry primary care as well as secondary specialtycare. They noted that diagnostic uncertainty, complexity,and discriminant variability are characteristic of chestpain assessment ... can beenhanced by creating multidisciplinary panels to explic-itly improve cross-disciplinary coordination of care.Competing interestsThe author(s) declare they have no competing interests.Authors'...
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Báo cáo y học: "Correlations of HBV Genotypes, Mutations Affecting HBeAg Expression and HBeAg/ anti-HBe Status in HBV Carriers"
... Mei Low 6, Yin Chyi Chan1 and So Har Ton1 1. School of Arts and Sciences, Monash University Malaysia, Petaling Jaya 46150, Malaysia 2. Faculty of Biotechnology, Malaysia University of Science ... and Technology, Petaling Jaya 47301, Malaysia 3. Discipline of Medicine, Blackburn Building D06, University of Sydney, NSW 2006, Australia 4. Institute of Molecular and Cell Biology, 61 Biopolis ... Using this method, 13.0 % (10/ 77) of the samples were found to be infected by HBV genotype B, 6.5 % (5/ 77) by genotype C, 1.3 % (1/ 77) by co-infections of genotypes B and C (Table 1). Nine...
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Báo cáo y học: "Management of Critically Ill Patients with Severe Acute Respiratory Syndrome (SARS)"
... FHKAM[Medicine]) is a specialist in respiratory medicine at the Division of Respiratory and Critical Care Medicine, Department of Medicine, PYNEH. Her research interest is in respiratory infections ... electrical instability in the myocardium and induction of arrhythmia [68]. 7. Infection control measures SARS is primarily transmitted by direct or indirect contact of mucous membranes (eyes, nose, or ... a host of cytokines [14,15]. In sicker patients, levels of pro-inflammatory cytokines (IL-1beta, IL-6, IL-8, IL-16, TNF-α) and TGF-β1 were higher, with slower decline on clinical recovery [14]....
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Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"
... measured by en-zyme-linked immunosorbent assay (Livzon Group Reagent Factory, Guangdong, China). HBV DNA The HBV DNA level was determined by quan-titative polymerase chain reaction (qPCR) (AcuGen HBV ... are abnormal, liver biopsy is strongly recommended in order to assess histology and prognosis. Our study demonstrated the signific-ance of liver biopsy in determining the causes of high ALT levels. ... with clinically and pathologically proven steatosis and 98 patients without steatosis were recruited into this study. The levels of fasting blood glucose (FBG), fasting insulin (FINS), triglyceride...
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Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... HA releasedinto the culture medium was measured by the sandwichbinding protein assay using hyaluronan binding protein(HABP) according to the manufacture’s instructions for thehyaluronic acid ... level of the hasoperon containing the hyaluronan synthase gene or theprotein level of hyaluronan synthase. Solubilization of theenzyme from membranes of MU-treated cells and addition of the ... little involvement of MU-meta-bolites in the inhibition of HA synthesis by MU in FM100cells. These above results indicate that something requiredfor a fully functional HA synthesis system is...
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Báo cáo Y học: Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase A site-directed mutagenesis study docx
... phe-nylalanine and serine in the enzyme from the yeast Rhodo-torula gracilis. The mutated proteins are catalyticallycompetent thus eliminating Tyr238 as an active-site acid/base catalyst. Y2 38F ... substitution of Y2 38 (Table 2).Steady-state and rapid reaction kinetics withD-alanineThe ability of the Y2 38 mutants to catalyseD-alanine/oxygen catalysis was measured by enzyme-monitoredturnover ... half-reaction of Y2 38 mutants withD-alaninewas measured by mixing anaerobically a solution of eachmutant enzyme with solutions containing varying concen-trations of D-alanine, such that...
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Báo cáo Y học: Role of histidine 42 in ascorbate peroxidase Kinetic analysis of the H42A and H42E variants pptx
... His42, may be in uen-tial in defining the stability of Compound II.The replacement of the distal histidine residue by alanineor glutamic acid clearly has a profound in uence on theability of the ... 5B).Recovery of H42A activitySteady-state and pre-steady-state analyses of H42A indi-cated that the enzyme was essentially inactive. Rateconstants for Compound I formation for H42A in thepresence of ... able to fully rationalize. Replacement of the distalHis42 by alanine renders the H42A enzyme essentiallyinactive, which is presumably directly linked to the verypoor reactivity of this variant...
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Báo cáo y học: "Treatment of Chronic HCV Infection in Special Populations."
... been in the developing of a non-invasive evaluation of liver function using the quantitative liver- spleen scan and the treatment of chronic hepatitis C. He was involved in many of the early studies ... immunodeficiency virus infection on the course of hepatitis C virus infection: a meta- analysis. Clin Infect Dis. 2001;33:562-569. Int. J. Med. Sci. 2006, 3 7317. Lindsay KL, Trepo C, Heintges T, ... articles. A study by Kaiser, et al [31] of induction dosing with daily Consensus interferon and Ribavirin (11 mg/kg/day) starting after week 4. Thirty patients in group A received Int. J. Med....
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