... per year in the mid-1980s (peak incidence), but declined to approximately 30,000 new cases per year in 1995.[13] The incidence of acute hepatitis < /b> C infection in the U.S. declined sharply in 1990, ... affected by many factors, including the age at time of infection, gender, ethnicity, and the development of jaundice during the acute infection (see Table 1). Table 1. Risk Factors for < /b> Developing ... time of infection, male gender, the degree of inflammation and fibrosis present on the liver biopsy, coinfection with human immunodeficiency virus (HIV) or hepatitis < /b> B virus (HBV), and comorbid conditions...