... Hermoso,J.,Pignol,D.,Kerfelec,B.,Crenon,I.,Chapus ,C. &Fontecilla-Camps, J .C. (1996) Lipase activation by nonionicdetergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether ... after coexpression of S132T and WWWmutants. Schematic dimeric structures of LPLin head-to-tail configuration after cotransfec-tion of inactive LPL mutants and recovery of catalytic activity (A). ... respect to how surface-loop positionsaffect substrate access to the catalytic site. In the closed form,the surface loop covers the catalytic site, which becomesinaccessible to solvent. Large conformational...