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Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids

Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids

Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids

... 107 Biodegradable Polymers Composed of Naturally Occurring α - Amino Acids Ramaz Katsarava and Zaza Gomurashvili 5.1 Introduction The synthesis and study of biodegradable polymers is ... densing agent [15 – 17, 61] . 120 5 Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids The covalent attachment of mono - ethanolamine to these polymers increases their hydrophilicity ... orientations of α - AAs in the polymeric backbones. Directional: Adirectional: Parallel: or Antiparallel: Mixed: 110 5 Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids prepared...
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Báo cáo khoa học: Computer-assisted mass spectrometric analysis of naturally occurring and artificially introduced cross-links in proteins and protein complexes potx

Báo cáo khoa học: Computer-assisted mass spectrometric analysis of naturally occurring and artificially introduced cross-links in proteins and protein complexes potx

... reduction of disul-fides [19]. It should be noted that this phenomenonenables assignment of pairs of in-source cleavage prod-ucts to corresponding disulfide linked peptides, thesum of the masses of ... conflicting disulfidelinkages; two of these correspond to a peptide withFig. 1. Part of the output sheet of the VIRTUALMSLAB analysis of the MALDI-FTICR-MS data of the RNase A digest peptide mixture. ... precisemapping of the cross-links [3,6,8]. To support massspectrometric analysis of cross-links in proteins, soft-ware tools have been developed [9–12] for the identifi-cation of digest fragments...
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Báo cáo khoa học: Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting polypeptide Ntcp docx

Báo cáo khoa học: Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting polypeptide Ntcp docx

... maintenance of theenterohepatic circulation of bile acids and therefore alsoparticipate in the homoeostatis of cholesterol. Members of SBATs are located either in apical membranes of ileumenterocytes, ... 2003 Site-directed mutagenesis of Ntcp (Eur. J. Biochem. 270) 1127Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependenttaurocholate ... Singh, D.N. & Fliegel, L.(2001) Functional analysis of polar amino acids residues inmembrane associated regions of the NHE1 isoform of the mam-malian Na+/H+exchanger. Eur. J. Biochem....
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Báo cáo khoa học: Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons ppt

Báo cáo khoa học: Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons ppt

... rat study, daily oral consumption of a glyco-nated form of catechin resulted in a serum concentra-tion of 34.8 ± 6.0 lm [50]. The amount of EPCG in asingle cup of green tea is  300 lm [51]. ... concentration of EPCGmay reach 60 lm in a 60 kg human after oral con-sumption of a single cup of tea. In the present study,the polyphenols were tested at a standardized concen-tration of 50 lm. ... sensitive method forquantitation of microgram quantities of protein utilisingthe principle of protein–dye binding. Anal Biochem 53,452–458.Neuroprotective effects of polyphenols N. Braidy et al.382...
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Handbook of biodegradable Polymers

Handbook of biodegradable Polymers

... References 1045 Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids 107 Ramaz Katsarava and Zaza Gomurashvili5.1 Introduction 1075.2 Amino Acid-Based Biodegradable Polymers (AABBPs) ... Degradation 26611.4.1 Nonbiological Degradation of Polymers 26611.4.2 Biological Degradation of Polymers 26711.5 Measuring Biodegradation of Polymers 26711.5.1 Enzyme Assays 26911.5.1.1 Principle ... Polymerization of Water-Soluble Monomers in the Presence of Crosslinking Agents 2209.2.1.2 Crosslinking of Water-Soluble Polymers 2219.2.2 Physical Elastic Hydrogels 2229.2.2.1 Formation of Physical...
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Handbook of biodegradable Polymers - Preface

Handbook of biodegradable Polymers - Preface

... creation of a highly versatile set of materials as a key component of new technologies. This collected series of texts, written by experts, has been put together to showcase the state of the art ... applications of biodegradable polymers, emphasizing the exciting potential of these materials. In the fi nal chapters, 15 – 16 , characterization methods and modelling techniques of biodegradation ... relevance of biodegradable dendrim- ers and dendritic polymers to the medical fi eld. Methods: Van der Zee gives a description of the methods used to quantify bio- degradability and the implications of...
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Microbial Production of Amino Acids in Japan

Microbial Production of Amino Acids in Japan

... various amounts of sodiumpyruvate, 5 g of ammonium acetate, 0.6 g of pyrocatechol, 0.2 g of sodiumsulfite,0.1 g of EDTA, and cells harvested from 100 ml of broth, in a total volume of 100 ml.The ... The mutant strain of E. coli which lacksl-proline-degrading enzyme was obtained and used for the host cells of produc-tion of l-hydroxyproline.Microbial Production of Amino Acids in Japan83Using ... successfulintroduction of the technology, various methods were searched for and deve-loped for microbial production of other amino acids. Today a whole array of amino acids are produced by microbial...
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Tài liệu Báo cáo khoa học: The mechanism of a-proton isotope exchange in amino acids catalysed by tyrosine phenol-lyase doc

Tài liệu Báo cáo khoa học: The mechanism of a-proton isotope exchange in amino acids catalysed by tyrosine phenol-lyase doc

... preparation of enantiomerically purea-de uterated (S)-amino acids [5–7].In the framework of the generally accepted notions of mechanisms of PLP-dependent enzymes the mechanism of the i sotopic ... definesautomatically the positions of the a-proton and the sidechain of any bound amino ac id. The lability of the a-protonobserved for a large number of amino acids [5] under theaction of TPL gives evidence ... orientation of the a-proton with respect to the cofa ctor plane [17], andshows that t he pattern of binding is the same for a variety of amino acids. It has been established [5] that for a number of amino...
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Báo cáo khoa học: The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids doc

Báo cáo khoa học: The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids doc

... deletion of the last 42 amino acids from NBD2 of SUR2 resultedin ATPase activity resembling that of NBD2 of SUR2A rather than that of NBD2 of SUR2B: this might indicate that these amino acids are ... activities of NBD2A and NBD2B couldresult from an inhibitory effect of the C-terminal 42amino acids of NBD2B or a stimulatory effect of theequivalent amino acids of NBD2A. To determinewhich of these ... amino acids. Figure 2A and Table 1 showthat the ATPase activity of NBD2-DC was greaterthan that of SUR2B but similar to that of NBD2A,favoring the idea that the last 42 amino acids of NBD2B...
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Báo cáo khoa học: Control of mammalian gene expression by amino acids, especially glutamine potx

Báo cáo khoa học: Control of mammalian gene expression by amino acids, especially glutamine potx

... inhibitory effect of some amino acids. Moreover, amino acids exert a wide range of effects via the activation of different signallingpathways and various transcription factors, and a number of cis elementsdistinct ... presence of aminoacid(s) resulted in inhibition of the DNA binding of the involved transcription factors. By contrast, thepresence of amino acid may also result in stimulation of the DNA binding of ... are not specific of an AARpathway suggesting that the effects of glutamine andpotentially those of other amino acids might dependnot only on cell types but also on the structure of thegene promoters.Finally,...
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