... Absorption of such drugs proceeds rapidly, because the absorbingsurface is greatly enlarged due to the formation of the epithelial brush border(submicroscopic foldings of the plasma-lemma). The absorbability ... encounters the non-kerati-nized, multilayered squamous epitheli-um of the oral mucosa. Here, the cellsestablish punctate contacts with eachother in the form of desmosomes (notshown); however, these ... prolong-ing the duration of the effect by retard-ing elimination, whereas the intensity of the effect is reduced. If two substanc-es have affinity for the same binding siteon the albumin molecule, they...