... among components of the humannucleotide excision repair pathwayChin-Ju Park and Byong-Seok ChoiDepartment of Chemistry, National Creative Initiative Center, Korea Advanced Institute of Science ... DNA inci-sions, respectively. Binding of XPG induces the release of XPC–hHR23B, whereas XPF–ERCC1 triggers exci-sion of the damaged DNA and the release of XPAand TFIIH. Subsequently, the newly ... for binding of the XPC–hHR23B complex to sites of DNA damage, hHR23Bstimulates XPC to function in NER and is alsonecessary for XPA–RPA-mediated displacement of theFig. 1. Scheme of the global...