Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Báo cáo Y học: Mydj2 as a potent partner of hsc70 in mammalian cells doc

Báo cáo Y học: Mydj2 as a potent partner of hsc70 in mammalian cells doc

... generation of the pQE-32-Mydj2 plasmid. The accuracy of the resu lting construct ( pQE-32-Mydj2) was v erified by DNA sequencing, and the plasmid was subsequently used to overexpress M ydj2–6·His in Escherichia ... f binding and release regulated b y their DnaJ cochaperones [2,3]. Based on the existense of three dinstict domains, namely: the highly conserved J domain...
Ngày tải lên : 17/03/2014, 17:20
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Báo cáo Y học: A chimeric scorpion a-toxin displays de novo electrophysiological properties similar to those of a-like toxins docx

Báo cáo Y học: A chimeric scorpion a-toxin displays de novo electrophysiological properties similar to those of a-like toxins docx

... min) BotXIV induced a plateau potential lasting for 110 ms followed by a long lasting and a very slowly decayed depolarization. In the case of the BotXIVM8-10, the evoked ÔplateauÕ is only 3–6 ms ... was decreased both during the activation and inactivation mechanisms, in presence of BotXIV the sodium current voltage dependence was decreased only in the case of...
Ngày tải lên : 08/03/2014, 23:20
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Báo cáo Y học: Purification, crystallization, NMR spectroscopy and biochemical analyses of a-phycoerythrocyanin peptides pptx

Báo cáo Y học: Purification, crystallization, NMR spectroscopy and biochemical analyses of a-phycoerythrocyanin peptides pptx

... of a phycobiliprotein lyase: both the attachment of phy- cocyanobilin and the isomerization to phycoviolobilin are cata- lyzed by the proteins PecE and PecF encoded by the phycoerythrocyanin operon. ... photochemistry; energy transfer. Phycobiliproteins are a class of chromoproteins bearing covalently bound linear tetrapyrrole (phycobilins) chro- mophores. They are predomina...
Ngày tải lên : 17/03/2014, 10:20
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Báo cáo Y học: Thiol-modifying inhibitors for understanding squalene cyclase function pdf

Báo cáo Y học: Thiol-modifying inhibitors for understanding squalene cyclase function pdf

... to wild-type (Table 1). Moreover, when the inhibitors could in principle overcome the barrier of the channel constriction and act directly in the active site cavity, as in the case of the C435S mutant, ... C435 may occur. The series of thiol-reacting agents used to study access of the substrate to the active site of SHC was also found to be a useful t...
Ngày tải lên : 17/03/2014, 23:20
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Báo cáo Y học: Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn’s disease ppt

Báo cáo Y học: Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn’s disease ppt

... moiety of LPS in the induction of cytokines, including tumor necrosis factor, and the phos- phate residue at the 4¢-position is a critical site for the activity [24]. Therefore, the monophosphoryl ... monitored by measuring phosphorus and hexose contents. The eluates were combined, dialyzed and lyo- philized. The combined fraction was used as an OPS-rich fraction...
Ngày tải lên : 31/03/2014, 23:20
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