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Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

Báo cáo y học:

Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

... GSTM1 OR GSTP1) AND (polymorphism OR polymorphisms OR SNP OR mutation) AND (cancer OR malign* OR carcinoma OR tumor OR tumour). The electronic search was supplemented by a manual review of ... Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not? Antonis Valachis1,2, Davide Mauri2,3,, Christodoulos Neophytou2, Nikolaos P. Polyzos2,4, ... trials: authors’ name, year of publication, country of origin, type of cancer, sample size, number of polymorphisms tested and results of the study. Studies were divided into two categories...
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Báo cáo y học:

Báo cáo y học: "Teaching child and adolescent psychiatry to undergraduate medical students - A survey in German-speaking countries"

... focusing on a separate area: “examination andstandards in examination,”“e-learning in medicine, ”“evaluation of teaching,”“practical year,” and “prepara-tion for final examination.” The practical year ... towards increased involvement of academic departments of child and adolescent psychiatry intraining medical students.IntroductionIn a recent review of child and adolescent psychiatry(CAP) in undergraduate ... a relatively early stage,with interdisciplinary cooperation just beginning. InSwitzerland, child psychiatry is integrated into the psy-chiatry curriculum and thus CAP is required in under-graduate...
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Báo cáo y học:

Báo cáo y học: "Refractive Status and Prevalence of Refractive Errors in Suburban School-age Children"

... importance of reducing near-work activity and preserving outdoor time in the setting of academically demanding sche-dules to reduce the prevalence of myopia. Acknowledgements We thank Prof. ... Military Medical University, Chongqing, People’s Republic of China  Corresponding author: Dr Zheng-Qin Yin, Southwest Hospital, Southwest Eye Hospital, Third Military Medical Univer-sity, Gaotanyan ... Bureau of Education and Bu-reau of Health in Yongchuan District approved the implementation of this study. Eye Examination Eye examinations were performed by a medical team consisting of three...
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Báo cáo y học:

Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"

... Availability for the duration of the entire study period Exclusion History of underlying inflammatory arthropathy or severe rheumatoid arthritis Hyperuricaemia (>440 μmol/l) and/ or past history of ... and Aflapin® conferred clinically and statis-tically significant improvements in pain scores and physical ability scores in OA subjects between base-line and day 90 (Table 3). Tukey's ... validated pain scores. Various parameters of serum biochemistry, hematology and urine analysis were carried out on each evaluation day. Safety was monitored by clinical and laboratory assessments...
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Tài liệu Báo cáo Y học: Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase pdf

Tài liệu Báo cáo Y học: Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase pdf

... for studying eukaryotic histidinephosphorylation/dephosphorylation.Keywords: dephosphorylation; N-phosphorylation; phos-phoamidase; phosphopeptide; protein histidine phospha-tase.Boyer and ... considerationalso for other combinations of phosphatases and interme-diary phosphorylated enzymes. Therefore, kinetic data onthe dephosphorylation of autophosphorylated ATP-citratelyase in the paper in press ... eukaryotes has beensparsely studied compared to protein serine/threonine and tyrosine phosphorylation. In an attempt to rectify this byprobing porcine liver cytosol with the phosphohistidine-containing...
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Tài liệu Báo cáo Y học: Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana docx

Tài liệu Báo cáo Y học: Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana docx

... activity and absorption spectra typical of cytochrome b5-type heme coordination, independent of pH(I.V.H. Kjærsga˚rd and K.G. Welinder, unpublished results).Therefore, AtP1 will stain poorly ... the ortholog of HRPC2 (91% aminoacid identity). Shinmyo et al. [64] have studied the promoteractivity and wound-induction of HRPC and -E types, and of AtPCa and AtPEa. Most remarkably, C2, and ... mV and thereafter with a variety of organic or inorganic reducing substrates, which are often oxidized toform radicals. Peroxidase activity was detected early in horseradish roots (reviewed in...
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Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx

Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx

... lipids wereextracted and the amount of labelled PtdIns wasdetermined (Table 1). In the absence of CMP, thepresence of AtPIS1 allows the incorporation of labelledinositol into PtdIns, according ... synthesis is puzzling or in anycase very difficult to analyse in terms of kinetics. From afunctional point of view, if a reaction reverse of synthesisfollowed by synthesis using CDP-DAGs different ... Phosphatidylinositol synthesis and exchange of the inositol headare catalysed by the single phosphatidylinositol synthase 1fromArabidopsisAnne-Marie Justin, Jean-Claude Kader and Sylvie CollinUniversite´Pierre...
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Tài liệu Báo cáo Y học: Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL pptx

Tài liệu Báo cáo Y học: Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL pptx

... AlexanderGirshovich who initiated and was actively involved in the beginning of this work. We wish to thank I. Gokhman for her help during thesubcloning of YbdQ. This research was supported by the MINERVAFoundation, ... ServicesDepartment of the Weizmann Institute by a single injection of 150 lg of the purified protein, followed by two boostershots of the same amount of protein at 2-week intervals.Serum was collected and ... then incubatedat 86 °C for 8 min. Typically, cell extracts (5–10 lgofprotein) were separated by SDS/PAGE using the standardLaemmli system [30] with 13% and 4% (w/w) acrylamide in the separating...
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Báo cáo Y học: Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N -acyl-D-amino acid amidohydrolase responsible for D-amino acid production pdf

Báo cáo Y học: Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N -acyl-D-amino acid amidohydrolase responsible for D-amino acid production pdf

... lgÆmL)1ampicillin in each well using a sterile toothpick and incubated at 37 °C overnight. The transformantswere screened for enzyme activity by adding to each well10 lL2mgÆmL)1lysozyme and incubating ... [12,13].N-acyl-D-amidohydrolase (EC.3.5.1.81, N-D-AAase) is anenzyme capable of catalysing the hydrolysis of N-acyl-D-amino acids to yield the correspondingD-amino acid and the organic acid. They ... containingD-methionine,D-leucine and D-alanine and against N-chloroacetyl-D-phe-nylalanine. Importantly, the enzyme does not act on theN-acetyl-L-amino acid derivatives. The enzyme was inhibitedby chelating...
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Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

... each of the other 19 amino-acid residues showed that Y8 1A, Y8 1G and Y8 1S are capable of making hexaprenylpyrophosphate (C30) [59]. The final products of Y8 1C, Y8 1H, Y8 1I, Y8 1L, Y8 1N, Y8 1T and Y8 1V ... presence of farnesyl hydroxyphosphonate. This brings the loop con-taining Arg264 and Arg266 close to the C1 hydroxy group of farnesyl hydroxyphosphonate, and an additional Mg2+site forms. In analogy, ... strategies for substrate binding and catalysis. First,they use hydrophobic interactions to bind the hydrocarbonmoiety of the allylic pyrophosphate substrate. Secondly,pyrophosphtae leaving is facilitated...
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