... the nuclear membrane hasadvanced dramatically in the recent years. We now know that protein residents of the nuclear membraneregulate processes as diverse as DNA replication andtranscription, ... emerin are redundant, however, func-tional overlap is likely, because mammalian MAN1and mammalian emerin do have many common part-ners (see below).MAN1 needs lamins in order to localize to ... membrane; LAP, lamina associated polypeptide; MH-domain, Mad homology domain; pRb, retinoblastoma protein;PP, protein phosphatase; RR-motif, RNA recognition motif; R-Smads, regulatory Smads; SANE,...