... C, Nardone AM, Columbaro M, Scarano G, Mattioli E, Sabatelli P, et al (2005) Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy ... mutations in lamin A, we have also observed major changes in chromosome positioning, away from the nuclear periphery, however, these cells appear to have A- type lamins as part of the nuclear lamina ... (2005) Both lamin A and lamin C mutations cause lamina instability as well as loss of internal nuclear lamin organization Exp Cell Res 304, 582–592 60 Crisp M, Liu Q, Roux K, Rattner JB, Shanahan...