Magnesium supplementtation reduces postoperative arrhythmias after cardiopulmonary bypass in pediatrics

... with increased risk of POA (infants having undergone repair of TOF, VSD,TGA, AVSD…) be given 50mg/kg Magnesium sulfate immediately after CPB CONCLUSIONS  Giving magnesium sulfate immediately after ... hemodynamic instability OBJECTIVES  Magnesium maintenance is an of essential myocardial cofactor for the transmembrane potential, magnesium deficiency decreases the threshold for arrhythmias ... saline (placebo group, n = 15) immediately after cessation of CPB  Results: in the placebo group, 27% JET developed in the ICU No JET was observed in the magnesium group (P =0.026) STUDIES  RCT(...

Báo cáo y học: "Prevalence of and risk factors for perioperative arrhythmias in neonates and children after cardiopulmonary bypass: continuous holter" docx

... perioperative arrhythmias in neonates and children after cardiopulmonary bypass: continuous holter monitoring before and for three days after surgery Journal of Cardiothoracic Surgery 2010 5:85 ... frequent in infants and children than in neonates For most types of arrhythmias surgical risk factors involving injury to a vulnerable part of the myocardial conduction system can be identified ... http://www.cardiothoracicsurgery.org/content/5/1/85 Page of Figure Period prevalences of arrhythmias The period prevalences of all arrhythmias as well as of the individual types of arrhythmias preoperatively, continuously...

Báo cáo y học: "Effect of short-acting beta blocker on the cardiac recovery after cardiopulmonary bypass" pot

... contractility when administered in the early stage In addition, esmolol improved the cardiac recovery and the heart oxygen delivery and consumption balance, which increased the myocardial energy stores ... List of abbreviations CPB: cardiopulmonary bypass; CABG: coronary artery bridge grafting Acknowledgements We thank Dr Liang Yongnian for his assistance in cardiopulmonary bypass work Authors’ contributions ... blocker on the cardiac recovery after cardiopulmonary bypass Journal of Cardiothoracic Surgery 2011 6:99 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online...

Báo cáo y học: "Myocardial contractile function in survived neonatal piglets after cardiopulmonary bypass" pptx

... elucidated in further studies comparing different types of myocardial protection Conclusions Applying an in vivo neonatal piglet model closely mimicking the clinical setting of cardiopulmonary bypass ... Cardiothoracic Surgery 2010, 5:98 http://www.cardiothoracicsurgery.org/content/5/1/98 hypercontractiliy after CPB This hypercontractility may be the result of the systemic inflammatory response on myocardial ... wall thickening indicates in some degree of Figure Performance of the left ventricular dP/dtmax in survived neonatal piglets in % of baseline value * P < 0.05 in comparison to the baseline value...

Báo cáo y học: "Effects of inosine on reperfusion injury after cardiopulmonary bypass" pps

... Despite the growing evidence of protective effects of inosine, the use of inosine for Page of prevention of reperfusion injury in the context of cardiopulmonary bypass has not yet been investigated ... intracoronary administration of a single bolus of acetylcholine (10-7 mol) expressed as percent change of coronary blood flow before and after cardiopulmonary bypass (CPB) at 60 of reperfusion (B) ... Effects of inosine on reperfusion injury after cardiopulmonary bypass Journal of Cardiothoracic Surgery 2010 5:106 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient...

Báo cáo y học: "Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass" pot

... One hour after end of surgery the distribution of the labeled neutrophils was analyzed by scintigraphy (Figure 6) In Figure 6A an example for the total body distribution of radioactivity is provided ... proposed that inhibition of neutrophil function by LIM may stabilize cardiac function Here, we report on our data showing the effects of LIM on CPB-related decrease of cardiac function in a porcine ... Journal of Inflammation 2007, 4:21 Background Cardiac surgery using cardiopulmonary bypass (CPB) is associated with impaired cardiac function at the end of surgery [1,2] However, the underlying...

Báo cáo khoa học: "Pulse contour analysis after normothermic cardiopulmonary bypass in cardiac surgery patients" pdf

... to and after cardiopulmonary bypass (CPB), and put (COPiCCOtherm) prior to and after cardiopulmonary bypass (CPB), and Bland-Altman plot of continuous arterial pulse contour analysis cardiac ... determination after calibration [17] In our study we investigated the validity of continuous CO measurement by pulse contour analysis after CPB The main advantage of COPiCCOpulse measurement after ... CO after CPB, the use of the uncalibrated continuous pulse contour cardiac output cannot be recommended after weaning from CPB Competing interests The authors declare that they have no competing...

Báo cáo y học: "Dextran-70 to modulate inflammatory response after cardiopulmonary bypass: potential for a novel approac" docx

... anti -inflammatory therapies Additionally, a combination of plasma inflammatory mediators and gene array analysis may lead to the identification of patients being more susceptible to harmful effects ... to cardiac transplantation and coronary artery bypass grafting J Thorac Cardiovasc Surg 1996, 111:469-77 Kawamura T, Inada K, Nara N, Wakusawa R, Endo S: Influence of methylprednisolone on cytokine ... Lassnigg A, Hamwi A, Vukovich T, Wolner E, Grimm M: Inflammatory response and myocardial injury following coronary artery bypass grafting with or without cardiopulmonary bypass Eur J Cardiothorac Surg...

Báo cáo y học: "Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery" ppt

... Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team: Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery Am J Kidney Dis 2005, ... Renin-angiotensin system and haemostasis gene polymorphisms and outcome after coronary artery bypass graft surgery Int J Cardiol 2005, 98:133-139 Eifert S, Rasch A, Beiras-Fernandez A, Nollert ... prospectively enrolled 220 consecutive adult patients (165 males and 55 females) with coronary artery disease (CAD) who were scheduled for coronary artery bypass grafting (CABG) using cardiopulmonary bypass...

Báo cáo khoa học: "Circulating inflammatory mediators and organ dysfunction after cardiovascular surgery with cardiopulmonary bypass: a prospective observational study" pot

... conception and design of the study and in the analysis and interpretation of data KCP, MF and DASAV conducted immunoassays and data acquisition and drafted the manuscript MLFM was involved in patient ... macrophage migration inhibitory factor (MIF) with postoperative organ failure scores (a) Sequential Organ Failure Assessment (SOFA) at day after surgery (b) Multiple Organ Dysfunction Score (MODS) at ... Thomas solutions Available online http://ccforum.com/content/10/2/R46 Figure Kinetics of inflammatory mediators at anesthesia induction and after cardiopulmonary bypass (a) Macrophage migration...

Báo cáo khoa học: " Hyperlactatemia during cardiopulmonary bypass: determinants and impact on postoperative outcome" ppsx

... m2) on CPB (calculated according to standard equations on the basis of arterial hemoglobin concentration and saturation and on pump flow indexed), the peak blood glucose, and the peak lactate concentration ... alone and HL plus HG; cp < 0.01 versus groups HL alone and HL plus HG; < 0.01 versus groups HL alone and HG alone; ep < 0.01 versus group no HL or HG and p = 0.014 versus group HG alone CPB, cardiopulmonary ... comorbidities (chronic renal failure, diabetes on medication, chronic obstructive pulmonary disease, and cerebrovascular accident), and laboratory assays (serum creatinine value [mg/dl] and hematocrit...

Báo cáo y học: " Determination of the threshold of cardiac troponin I associated with an adverse postoperative outcome after cardiac surgery: a comparative study between coronary artery bypass graft, valve surgery, and combined cardiac surgery" ppt

... statistical analysis and participated in the design of the study BR participated in the design and coordination of the study and performed the statistical analysis All authors read and approved the ... determination of a particular threshold in each type of cardiac surgery, the accuracy of cTnI was significantly greater in CABG than in valve surgery or combined surgery, and the specificity of ... outcome in cardiac surgical patients [11,12] A technician who was unaware of the clinical and electrocardiogram data performed the assays cTnI was analyzed with a sensitive and highly specific immunoenzymometric...

Báo cáo y học: "Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation" ppt

... Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation Critical ... anti -inflammatory properties have not yet been investigated in the context of post-resuscitation care Thus, a Page of 11 combination of hypothermia and anesthetic post-conditioning with sevoflurane ... of hypothermia on neuroprotection are considered to be due, in part, to suppression of post-injury pro -inflammatory factors by microglia However, the role of hypothermia in modulating anti-inflammatory...

Báo cáo y học: "entral venous oxygen saturation and blood lactate levels during cardiopulmonary bypass are associated with outcome after pediatric cardiac surgery" potx

... Central venous oxygen saturation and blood lactate levels during cardiopulmonary bypass are associated with outcome after pediatric cardiac surgery Critical Care 2010 14:R149 Submit your next ... morbidity and mortality in pediatric cardiac operations are still lacking At present, venous oxygen saturation may be continuously measured during CPB, by using specific detectors placed in the venous ... values of venous oxygen saturation during CPB are generally interpreted as an increased peripheral oxygenextraction rate due to an oxygen delivery (DO2) inadequate to sustain the oxygen consumption...

Báo cáo y học: " Endothelial Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery: a prospective observational stud" pptx

... conventional cardiopulmonary bypass J Thorac Cardiovasc Surg 2003, 125:843-848 doi:10.1186/cc10051 Cite this article as: Klein et al.: Endotoxemia related to cardiopulmonary bypass is associated with increased ... surgery is uncommon compared to previous reports • Endotoxemia correlates with the duration of surgery • Patients who have cardiopulmonary bypass associated endotoxemia are at a significantly increased ... in study design, data collection and analysis RN was responsible for statistical analysis and contributed to the manuscript ADR was involved in performing the assay and data analysis, and contributed...

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