Interventions for idiopathic steroid resistant nephrotic syndrome in children

Báo cáo y học: " Prolonged extracorporeal membrane oxygenation therapy for severe acute respiratory distress syndrome in a child affected by rituximab-resistant autoimmune hemolytic anemia: a case report" pptx

Báo cáo y học:
... steroid therapy with intravenous methylprednisolone at 2mg/kg/day was administered for days (Figure 1) An adequate Hb increase was obtained and the child was discharged after 10 days with oral prednisone ... with cyclophosphamide 10mg/kg/ day for 10 days and methylprednisolone 40mg/kg/day for days, which was tapered over 20 days Hb level increased and the patient was discharged 10 days later in good ... gave final approval of the version to be published References Ware RE, Rose WF: Autoimmune hemolytic anemia In Nathan and Oski’s Hematology of Infancy and Childhood Edited by Nathan DG, Orkin...
  • 5
  • 118
  • 0

GENETICS OF NEPHROTIC SYNDROME IN SINGAPORE PAEDIATRICS PATIENTS

GENETICS OF NEPHROTIC SYNDROME IN SINGAPORE PAEDIATRICS PATIENTS
... Mutations  in TRPC6  resulted in a gain of function.  Mutations in WT1 affect the DNA‐binding affinity of WT1  to the target gene. Heterozygous de novo mutations in WT1 resulting in the inability of ... C‐terminal  domain of podocin (Huber et al., 2001). The phosphorylation of nephrin also increases  the binding of nephrin and podocin (Li et al., 2004).     TRPC6  TRPC6  is  a  member  of the  ... Nephrin and other variants of nephrotic syndrome Although  nephrin  is  apparently  pivotal  in development  of CNF,  the  role  of nephrin  in other variants of NS is also of interest Lahdenkari et al. investigated NPHS1 in patients ...
  • 160
  • 41
  • 0

GENETICS OF NEPHROTIC SYNDROME IN SINGAPORE PAEDIATRICS PATIENTS 2

GENETICS OF NEPHROTIC SYNDROME IN SINGAPORE PAEDIATRICS PATIENTS 2
...   (20 11)  Diagnosis  Gender 22 0  10  4  M  22 3  6  5  F  23 1  11  9  M  23 2  6  3  M  23 5  18  9  M  23 6  10  7  M  23 21   3  M  24 4  9  2 25 2  19  17  M  25 3  4  4  M  25 4  14  11  M  25 5  ... A/A  A/A  154 Patient  no.  153  156  159  160  161  1 62 164  169  170  1 72 173  174  21 21 22 22 23 23 23 23 23 24 25 25 3  NPHS1  Gender  F  M  M  M  F  M  M  M  M  M  M  ... 0.93      158 c .23 98C>T (n= 125 )  CC  CT  c .28 71G>A (n= 125 )  GG  GA  c. 323 0A>G (n =22 1)  AA  AG  c.3315G>A (n =22 1)  GG  GA  AA      122  (98%)  3  (2%125  (100%)  0 (0%)  21 7 (98%)  4  (2% )  95 (43%)...
  • 25
  • 25
  • 0

New ESPGHAN guidelines for the diagnosis of Coeliac Disease in Children and Adolescents pptx

New ESPGHAN guidelines for the diagnosis of Coeliac Disease in Children and Adolescents pptx
... Change in clinical paradigm Definitions of coeliac disease New diagnostic guidelines Algorithms Interlaken ESPGHAN criteria (1979) Small intestinal biopsy: villous atrophy Gluten free diet for 1-2 ... unpublished Towards a new definition of coeliac disease  Chronic  Multi-organ  Small intestinal inflammation  Transglutaminase-related ESPGHAN working group, 2011 Suggestion: New definition  an immune-mediated ... 04-E029-2, 2004 NICE Clinical Guidelines 86 Coeliac Disease: Recognition and assessment of coeliac disease UK, May 2009 Guidelines: AHRQ (USA, 2004) Main issues Sensitivity/specificity of serological...
  • 33
  • 163
  • 0

báo cáo hóa học: " A radial basis classifier for the automatic detection of aspiration in children with dysphagia" doc

báo cáo hóa học:
... classifying a vibration signal as an aspiration when a swallow has actually occurred, whereas a false negative (FN) is the event of classifying a vibration signal as a swallow when an aspiration has ... implies that the mean and variance of the signal not change over time Determination of stationarity is important in selecting the appropriate analytical method, such as in the fractal characterization ... Aspiration classifier The proposed feature combinations and radial basis classifier achieved approximately 80% adjusted accuracy in classifying aspirations and swallows This accuracy level already exceeds...
  • 17
  • 131
  • 0

Báo cáo y học: "The evidence base for chiropractic treatment of musculoskeletal conditions in children and adolescents: The emperor''''s new suit" pdf

Báo cáo y học:
... words, there is no first level evidence available in relation to the effectiveness of manual therapy for spinal disorders in the young population As for the rest of the musculoskeletal system, only ... subject to bias) and non-randomized clinical studies were included if they investigated the effect of manual therapy on musculoskeletal disorders in children and/ or adolescents Therefore, we excluded ... treatment in the same manner as adults Logically, there might be considerations for treating children with manual therapy that not apply to adults [27] and therefore, treating children with therapies...
  • 4
  • 111
  • 0

Báo cáo khoa học: " Acupuncture treatment for idiopathic Horner''''s syndrome in a dog" doc

Báo cáo khoa học:
... acupoints that are used for treating facial paralysis in human Oriental medicine [14,16] These acupoints were treated bilaterally at each point with a filiform stainless-steel needle (AP needle No ... first acupoint of the Gallbladder meridian Tong Zi Liao means ‘fossa of bone near the pupil’ GB-1 is located at the lateral corner of the lateral canthus The ST-4 and GB-1 are local acupoints that ... needling appeared to have a dramatic effect on idiopathic Horner’s syndrome In addition, more cases should be investigated in order to determine the efficacy of acupuncture in Horner’s syndrome...
  • 3
  • 141
  • 0

Báo cáo y học: "Hip joint replacement surgery for idiopathic osteoarthritis aggregates in families" doc

Báo cáo y học:
... false-positive result) In the present study, using joint replacement surgery for idiopathic OA as a qualitative measure of joint failure, we sought to determine how hip joint failure and knee joint failure ... laboratory, and physical examination findings were reviewed Siblings who had joint replacements were interviewed to ascertain the reason for their joint replacement Probands or affected siblings ... the original patient cohorts were stratified into subgroups based on sex, affected joint site, number of affected joints, and severity of joint disease, such as having undergone joint replacement...
  • 9
  • 74
  • 0

Báo cáo y học: "Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus" pps

Báo cáo y học:
... in the expression and binding of GRs in SS patients compared with those in controls except for the binding of GR in T lymphocytes Similar results were also found in patients with nephrotic syndrome ... specificity of staining in FCM was established by using non-specific mouse IgG1 and unlabelled Dex Additionally, to evaluate the reproducibility of FCM analysis of GR, GR expression and binding in T lymphocytes ... SLE patients were divided into the SR and the SS groups accordingly GR expression and binding in T lymphocytes (CD3/GR) and monocytes (CD14/ GR) of SR, SS patients and controls were measured by...
  • 11
  • 138
  • 0

Báo cáo y học: " Perioperative infusion of low- dose of vasopressin for prevention and management of vasodilatory vasoplegic syndrome in patients undergoing coronary artery bypass grafting-A double-blind" potx

Báo cáo y học:
... al.: Perioperative infusion of lowdose of vasopressin for prevention and management of vasodilatory vasoplegic syndrome in patients undergoing coronary artery bypass grafting-A double-blind randomized ... in the vasopressin actions Conclusions In summary, infusion of an “ultra-low” dose vasopressin (0.03 U/min) during cardiopulmonary bypass and for the first four hours after coronary artery bypass ... Ten minutes before termination of the cardiopulmonary bypass, a solution of norepinephrine, at a dose of 0.03 μg/Kg/min was routinely administered (in continuous iv infusion) , and it was individually...
  • 12
  • 65
  • 0

báo cáo khoa học: "E-learning interventions are comparable to user’s manual in a randomized trial of training strategies for the AGREE II" pps

báo cáo khoa học:
... intervention arm passed the online training with the practice PG The multivariate analysis of variance failed to show a difference in participants’ reporting of mental effort as a function of training ... Grimshaw J, Hunt C, for the AGREE Collaboration: Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project Qual ... User’s Manual to determine their effects on various measures related to performance on and attitudes toward the AGREE II The goal was to identify the best strategy to facilitate the AGREE II’s appropriate...
  • 10
  • 112
  • 0

Báo cáo y học: "Gabapentin for complex regional pain syndrome in Machado-Joseph disease: a case report" pot

Báo cáo y học:
... again by wheelchair Discussion In this case, all of the clinical features of pain- such as spontaneous continuing regional pain with cutaneous thermal change, thermal hypersensitivity, focal edema, ... of this journal Figure Visual analogue scale (VAS) and daily dosage of gabapentin (GBP) in the hospital Our patient’s pain was gradually resolved from to on the VAS by an increase in GBP from ... Neuropathic pain: a maladaptive response of the nervous system to damage Annu Rev Neurosci 2009, 32:1-32 Schwartzman RJ, Erwin KL, Alexander GM: The natural history of complex regional pain syndrome Clin...
  • 3
  • 109
  • 0

báo cáo khoa học: " High-dose steroid therapy for idiopathic optic perineuritis: a case series" doc

báo cáo khoa học:
... at a dose of 30 mg/day at her previous hospital After we performed steroid pulse therapy at our hospital for Cases and 3, there was no recurrence in Case 3, and no subsequent recurrence in Case ... clinical and radiographic features Arch Ophthalmol 2001, 119(9):1299-1306 doi:10.1186/1752-1947-4-404 Cite this article as: Tatsugawa et al.: High-dose steroid therapy for idiopathic optic perineuritis: ... treponemal-antibody; MR: magnetic resonance; Author details Department of Ophthalmology, Hiroshima Prefectural Hospital, Hiroshima, Japan, 1-5-54, Ujinakanda, Minami-ku, Hiroshima 734-8530, Japan Department...
  • 4
  • 142
  • 0

Xem thêm

Nạp tiền Tải lên
Đăng ký
Đăng nhập