Exhaled nitric oxide measurements
Exhaled nitric oxide measurements
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Báo cáo y học: "Effect of allergen-specific immunotherapy with purified Alt a1 on AMP responsiveness, exhaled nitric oxide and exhaled breath condensate pH: a randomized double blind study" ppsx
... weal was ≥3 mm larger in diameter than that of the glycerinated saline Data analysis An intention-to-treat approach was followed in the analysis of efficacy data All patients with a baseline and ... profile of SIT with Alt a1 is superior to that detected with a conventional standardized extract of Alternaria Conclusions Although SIT with Alt a1 is well tolerated and induces an allergen-specific ... placebo-controlled study of Alternaria alternata immunotherapy: Clinical efficacy and safety Pediatr Allergy Immunol 2008, 19:67-75 Asturias JA, Ibarrola I, Ferrer A, Andreu C, Lopez-Pascual...
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Báo cáo y học: " Exhaled nitric oxide and clinical phenotypes of childhood asthma" docx
... proximal and distal airway nitric oxide categories Respir Res 2010, 11:47 doi:10.1186/1465-9921-12-65 Cite this article as: Mahut et al.: Exhaled nitric oxide and clinical phenotypes of childhood ... asthma, showing that exhaled NO does help to describe a clinically useful phenotype despite its ability to describe underlying pathophysiology (inflammation and modified airway smooth muscle function) ... clinical and physiological correlates of exhaled NO, and the degree of FENO variance explained by the correlates The second approach used a more complex statistical tool, namely cluster analysis,...
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Báo cáo y học: " Diagnosing asthma in general practice with portable exhaled nitric oxide measurement – results of a prospective diagnostic study" ppsx
... history, physical examination, bodyplethysmography and bronchial provocation results Data Analysis Baseline data is presented descriptively Two-by-two contingency tables of FENO values vs asthma ... diagnosing severe asthma has already been demonstrated [3] In mild asthma in particular, an airway obstruction is often not present, thus leading to diagnostic uncertainty Serial peak-flow measurement ... sensitivity analyses showed that the cut-off point of FENO remained the same when actually non-smoking patients initially labelled as COPD or overlap were classified as asthma patients with fixed airway...
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Báo cáo y học: " ''''Diagnosing Asthma in General Practice with Portable Exhaled Nitric Oxide Measurement – Results of a " pps
... say "FENO £16 ppb", "8 1% (95% CI 6 4–9 1 )" should say "8 2% (95% CI 7 2– 90 )" and "3 4" should say "6 8" In line 3, "FENO £12 ppb" should say "FENO £16 ppb" and "five" should say "three" In line "1 2 ... £1 6" In the second paragraph, in line 1, "five" should say "three" In line 5, "1 6 patients had FENO £12 ppb" should say "3 7 patients had FENO £ 16 ppb" Also in line 5, "three" should say "two" and ... 6 3–8 9 )" In line 6, "1 6 (15.8% )" should say "3 7 (36.6% )", "FENO £12 ppb" should say "FENO £16 In the Discussion section, in line 4, "8 1 %" should say "8 2 %" and in line 5, "FENO £1 2" should say "FENO...
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Báo cáo y học: " Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics" docx
... exhaled nitric oxide and exhaled 8-isoprostanes by body mass index in adults with asthma [See additional file: figure keys] Association of exhaled nitric oxide and exhaled 8-isoprostanes by body ... exhaled 8-isoprostanes by body mass index in healthy non-asthmatic adults Figure Association of exhaled nitric oxide and exhaled 8-isoprostanes by body mass index in healthy non-asthmatic adults [See ... leptin and adiponectin with levels of exhaled NO and exhaled 8-isoprostanes in subjects with stable asthma and healthy controls In subjects with asthma, BMI and the systemic leptin/adiponectin...
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Báo cáo y học: " Exhaled nitric oxide and urinary EPX levels in infants: a pilot study" potx
... Simpson, LA Lowe, A Woodcock, A Custovic, National Asthma Campaign Manchester Asthma and Allergy Study G, Urinary eosinophilic protein X, atopy, and symptoms suggestive of allergic disease at years ... dampness, measured as windowpane condensation Measuring FeNO by the present method may be an interesting non-invasive way of evaluating early inflammation in the airways Page of 8 Acknowledgements ... the sanitary towel In our own analysis of five healthy volunteers, we found a marked decrease in urinary EPX/ c levels after incubation of urine in the sanitary towel However, this systematic...
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Exhaled nitric oxide measurement in asthma
... Most exhaled NO found in low exhaled flow rates is produced by the airways During atopy (with or without asthma) , there is an increase in airway NO production (J’awNO ), explaining the increase in ... FENO In asthma, J’awNO (and FENO ) corre-lates with the eosinophilic airway inflammation Predictive value of FENO in diagnosing asthma • FeNO can help in the diagnosis of asthma when clinical ... concentration of exhaled nitric oxide • J’awNO : airway NO production • CANO: alveolar concentration of NO CONTENTS: • Introduction • FeNO in diagnose asthma • FeNO in manage asthma + Predicting response...
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Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"
... synthase (NOS; EC 1.14.13.39), and the citrulline generated as a by-product can be recycled to arginine by successive actions of argininosuccinate synthetase (AS; EC 6.3.4.5) and argininosuccinate ... accidents and also during incidents involving anesthesia To understand the role of citrulline- NO cycle enzymes, GS and the oxidative status in anoxia and reperfusion, NOS, AS, AL, GS and arginase ... Ca2+ influx (41) The increased activity of NOS and the increased formation of NO in brain in anoxia as observed by increase in NOx concentration in this study support the earlier findings of NO involvement...
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Báo cáo y học: "Does Flavanol Intake Influence Mortality from Nitric Oxide-Dependent Processes
... 1,193/100,000/year in those over 60 years of age Cancer followed with a frequency of 74.71/100,000/year The frequency in males (77.6/100,000/yr) exceeded only slightly the frequency in females ... 100,000 over years for the conditions specified in the hypothesis that a very high dietary intake of flavanoids might predict Note the remarkable year-to-year consistency in Panama and the very much ... in Table The stability year-by-year for each diagnosis in Pa- nama was evident In the case of cancer, the frequency over the five years ranged from 64.2 to 72.2/100,000/yr with a mean of 68.4±1.60...
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Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf
... the rate of electron import into the FMN subdomain and the resulting formation of FMNH2 The extent to which KeqA or the rate of FMNH2 formation influences electron flux through the NOS flavoprotein ... NOS, the second electron is provided to the hemedioxy species by a bound H4B cofactor rather than by the flavoprotein domain [16] The H4B radical is then reduced within the enzyme by the flavoprotein ... incomplete extents as the flavoprotein cycles through its 3- and 2 -electron reduced states during catalysis This, in turn, can impact the rate of electron exit and flux through the flavoprotein Two studies...
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Tài liệu Báo cáo khoa học: Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells pdf
... localization of iNOS to apical domains of intestinal epithelial cells Particulate fraction association of iNOS in vivo In order to determine the distribution of iNOS in intestinal epithelial cells in vivo, ... epithelial cells Apical distribution of iNOS in intestinal epithelial cells To get more insight into the localization of iNOS in intestinal cells, Caco-2 cells were investigated Caco-2 FEBS Journal ... which, in intestinal cells, could be bacteria present in the intestinal lumen This hypothesis is supported by positioning of iNOS on the apical side of intestinal crypts Recently PDZ-binding a2...
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Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx
... well as NO production Accordingly, we concluded that the enhancing effect of TS on LPS/IFN -induced NO production is caused by enhancement of iNOS protein induction Effects of a-T and its derivatives ... amphiphilic structure of the polar carboxyl moiety and the hydrophobic isoprene moiety The enhancing effect of TS on LPS/IFN -induced NO production was inhibited by the coexistence of a-T, TA and TN ... the VSMC, but TS was not hydrolyzed to a-T and succinic acid [32] Accordingly, the enhancement of LPS/IFN -induced NO production is attained by TS itself rather than a derivative TS enhanced LPS-dependent...
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Báo cáo khoa học: Space, time and nitric oxide – neuronal nitric oxide synthase generates signal pulses pptx
... reactivity of nitric oxide J Exp Med 169, 101 1–1 020 Abu-Soud HM & Stuehr DJ (1993) Electron transfer in the nitric- oxide synthases Nitric oxide synthases reveal FEBS Journal 276 (2009) 667 7–6 688 ª ... purview and parameters Nat Rev Mol Cell Biol 6, 15 0–1 66 Lancaster J (1997) A tutorial on the diffusibility and reactivity of free nitric oxide Nitric Oxide 1, 1 8–3 0 Salerno JC (2008) Neuronal nitric ... nitric oxide synthase indicating a neural role for nitric oxide Nature 347, 76 8–7 70 Knowles RG, Merrett M, Salter M & Moncada S (1990) Differential induction of brain, lung and liver nitric oxide...
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Báo cáo khoa học: Interference with the citrulline-based nitric oxide synthase assay by argininosuccinate lyase activity in Arabidopsis extracts docx
... determine the source of arginine-dependent NOS activity in plants, using crude protein extracts from Arabidopsis leaves By employing the citrulline-based NOS assay, an arginine-dependent activity ... 4) The plate was then autoradiographed The markers were visualized by ninhydrin staining, and then marked as dashed lines on the autoradiogram The origin was marked with an ink spot Argininosuccinate ... Argininosuccinate is the immediate precursor to arginine in the urea cycle, and is converted to arginine and fumarate by argininosuccinate lyase (ASL; EC 4.3.2.1; Fig 5) Argininosuccinate is normally...
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