EndovascularTreatment of cerebral arteriovenous malformations

EndovascularTreatment of cerebral arteriovenous malformations

EndovascularTreatment of cerebral arteriovenous malformations
... agents, with a complication rate of 4.8% - Neuroendovascular embolization represents a critical component of the multidisciplinary management of cerebral arteriovenous malformations - Safe, effective ... treatment of unruptured AVMs beneficial? Benefits Risks Crowford : ( symtomatic AVM10,4years) - Rish of Hemorrhage: 42% - Rish of Dead: 29% - Rish of Neurological Deficits : 27% - Rish of Epilepsy: ... Complication risk of endovascular embolization for cerebral arteriovenous malformation (http://www.ncbi.nlm.nih.gov/pubmed/20950972)  CONCLUSIONS: Embolization of brain AVMs is safe, 95.9% of patients...
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Báo cáo khoa học: Recent insights into cerebral cavernous malformations: the molecular genetics of CCM pot

Báo cáo khoa học: Recent insights into cerebral cavernous malformations: the molecular genetics of CCM pot
... clinical care of the patients and were an important step towards the understanding of the mechanisms of this disorder This minireview summarizes the advances in CCM molecular genetics and the remaining ... exons 17 and 18 of CCM1 , one deletes exon of CCM2 and one deletes exon of CCM3 The last two deletions have been used to map potential relevant interaction domains of CCM2 and CCM3 [23,26] However, ... loss, within affected cells, of the two alleles of a given CCM gene Loss of one of the alleles (first hit) would be the result of a germline mutation and loss of the second allele (second hit)...
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Báo cáo khoa học: Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype pptx

Báo cáo khoa học: Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype pptx
... function and lesion biology By exploring the function of the CCM genes in animal models this gap is being CCM animal models bridged Animal models have demonstrated the central importance of endothelial ... increase in both the intracerebral hemorrhage phenotype of rap1b and the cardiac developmental phenotype of san The zebrafish experiments demonstrate the role of the CCM genes in cardiac and vascular ... further understand the human phenotype Recent investigations have further refined our understanding of this phenotype, and bear reviewing in this manuscript In human CCM disease, the lesions exhibit...
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Báo cáo khoa học: Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction doc

Báo cáo khoa học: Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction doc
... KRIT1, a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein Proc Natl Acad Sci U S A 99, 10677–10682 Boulday G, Blecon A, Petit N, Chareyre F, Garcia LA, Niwa-Kawakita ... AI, Aebersold R, Raught B & Gingras AC (2009) A PP 2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous ... 38 angiogenesis: implications for human cerebral cavernous malformations Dis Model Mech 2, 168–177 Whitehead KJ, Chan AC, Navankasattusas S, Koh W, London NR, Ling J, Mayo AH, Drakos SG, Marchuk...
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Báo cáo khoa học: Molecular basis of cerebral neurodegeneration in prion diseases pdf

Báo cáo khoa học: Molecular basis of cerebral neurodegeneration in prion diseases pdf
... mediate an interaction of PrPC with accessory proteins, such as transmembrane proteins involved in PrP-induced signaling Alternatively, deletion of the HD could indirectly affect intermolecular interactions ... basolaterally, indicating that this domain acts as a dominant sorting signal Vice versa, Dpl or PrPC lacking the HD were found mainly at the apical surface of MDCK cells [36] An interesting activity of PrPC ... neurodegeneration in prion diseases Dpl- and PrPDF-induced neurodegeneration [32,35] This effect is difficult to understand in the light of the differential sorting of PrPC and Dpl However, in polarized...
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báo cáo hóa học: " Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy" doc

báo cáo hóa học:
... duplication, chitotriosidase testing was performed, and in all cases no activity was measurable Each of these cases was excluded from further analysis Therefore, chitotriosidase activity could be assayed ... these patients had active disease at the time samples were collected Of the 42 CALD patients studied, in one case a plasma sample was not obtained, and in another and no spinal fluid was available ... Plasma Chitotriosidase Determinations Are Associated with MRI and Functional Scores: For ALD patients with cerebral disease, the correlation of plasma chitotriosidase activity prior to transplantation...
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Báo cáo sinh học: " Research Article Time-Frequency Characterization of Cerebral Hemodynamics of Migraine Sufferers as " pptx

Báo cáo sinh học:
... frequency content of the NIRS oxygenation signals From a methodological point of view, the use of timefrequency analysis proved essential in the characterization of the subjects’ cerebral hemodynamics ... performing breath-holding, whereas MwA subjects shows higher values Our study showed that the time-frequency analysis of these signals is crucial if the assessment of cerebral hemodynamics is the clinical ... Swiat, M Tomaszewski, and J Krejza, Cerebral hemodynamics and investigations of cerebral blood flow regulation,” Nuclear Medicine Review, vol 10, no 1, pp 29–42, 2007 [4] R Aaslid, Cerebral autoregulation...
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Báo cáo y học: "Electroconvulsive therapy and determination of cerebral dominance" pptx

Báo cáo y học:
... handwriting position, language laterality, and the Levy-Nagylaki model of handedness and cerebral organisation Neuropsychologia 1980, 18:99-102 Beaumont JG, McCarthy R: Dichotic ear asymmetry ... speech dysfunction after ECT Traditionally, the routine clinical determination of cerebral dominance has been through the assessment of hand, foot and eye dominance It certainly is an easy and inexpensive ... R: Memory and electroconvulsive therapy Am J Psychiatry 1965, 122:546-554 Fleminger JJ, Horne DJ, Nair NPV, Nott PN: Differential effect of unilateral and bilateral ECT Am J Psychiatry 1970,...
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Báo cáo y học: "Daily rhythm of cerebral blood flow velocity" pdf

Báo cáo y học:
... and cerebral blood flow velocity in healthy humans Acta Physiol Scand 2002, 175(1):1-9 Yan H, Shan Y, Huang W, Bai Y, Zhang Q: Effect of body position changes and circadian rhythm on cerebral blood ... hypothesis that there is tight coupling of normal neuronal activity and blood flow was formulated over 100 years ago [36] The drop in CBFV may be a consequence of the lowered cerebral activity ... difference in the CBFV rhythm with Page of 11 (page number not for citation purposes) Journal of Circadian Rhythms 2005, 3:3 respect to the CBT rhythm may help explain previous findings of lower CBFV...
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báo cáo khoa học: " Paradoxical embolism following thromboaspiration of an arteriovenous fistula thrombosis: a case report" pot

báo cáo khoa học:
... (CT) scan of the abdomen revealed a perigraft hematoma Three days later (on day 25), she developed thrombosis of her AV fistula Anticoagulation treatment with danaparoid sodium (Orgaran) was reinitiated ... to the preparation of this case report PL is the supervisor of the management and DS has managed the patient and written this case report All authors read and approved the final manuscript Competing ... specificity approach 96% [9] The treatment of paradoxical embolism includes antiplatelet agents, systemic anticoagulation and closure of the PFO [10] In its acute phase, paradoxical embolism is usually...
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Báo cáo y học: " A pattern of cerebral perfusion anomalies between Major Depressive Disorder and Hashimoto Thyroiditis" doc

Báo cáo y học:
... SPECT The evaluation of images was both qualitative and semiquantitative On visual analysis, anomalies in cerebral areas where the uptake of the radioactive drug was decreased in at least three ... Cite this article as: Hardoy et al.: A pattern of cerebral perfusion anomalies between Major Depressive Disorder and Hashimoto Thyroiditis BMC Psychiatry 2011 11:148 Submit your next manuscript ... study indicates that MDD is associated with asymmetry in cerebral diffuse hypoperfusion, right and left Frontal hypoperfusion, right Temporal hypoperfusion and Parietal perfusion Perfusion anomalies...
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Báo cáo y học: " Bench-to-bedside review: A possible resolution of the glucose paradox of cerebral ischemia" pdf

Báo cáo y học:
... together, they unequivocally point at CT as the culprit behind the glucose paradox of cerebral ischemia The CT hypothesis is consequently being offered to explain this paradox instead of the lactic ... acidosis hypothesis Summary The glucose paradox of cerebral ischemia, the phenomenon of preischemic hyperglycemia-aggravated postischemic outcome, has been blamed on the accumulation of lactate ... Tsubota S, Adachi N, Chen J, Yorozuya T, Nagaro T, Arai T: Dexamethasone changes brain monoamine metabolism and aggravates ischemic neuronal damage in rats Anesthesiology 1999, 90:515-523 Bruno A, ...
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Báo cáo y học: "Argon: Neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury" pdf

Báo cáo y học:
... III, Eberwine JH, Meaney DF, McIntosh TK: Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization ... neuroprotective potential in both in vitro models of ischemia and traumatic brain injury Protection was observed with three different concentrations of argon (25, 50 and 74%), either directly applied after ... of xenon and helium in an in vitro model of traumatic brain injury Crit Care Med 2008, 36:588-595 Dingley J, Tooley J, Porter H, Thoresen M: Xenon provides shortterm neuroprotection in neonatal...
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INVESTIGATION ON CLINICAL FEATURES, BRAIN IMAGING, a NUMBER OF RIKS FACTORS AND THE VALUE OF d DIMER IN DIAGNOSIS OF CEREBRAL VENOUS THROMBOSIS

INVESTIGATION ON CLINICAL FEATURES, BRAIN IMAGING, a NUMBER OF RIKS FACTORS AND THE VALUE OF d DIMER IN DIAGNOSIS OF CEREBRAL VENOUS THROMBOSIS
... types of veins They emerge from the brain and lie in the subarachnoid space They pierce the arachnoid mater and the meningeal layer of the dura and drain into the cranial venous sinuses Blood from ... venography (MRV) imaging provide a best non-invasive technique for the diagnosis of CVT which is considered as a gold standard and can replace invasive conventional cerebral angiography and is used ... headache and paraparesis According to the study of Le Van Thing and Trinh Tien Luc, seizures symptom accounted 32%, ranked the 3rd position after headache and cranial nerve paralysis According...
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