Engineers Notebook II A Handbook Of Integrated Circuit Applications

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)
... sampling until injection to GC, and from the standard solution to a test specimen) In principle, the sampling, extraction and GC analysis should be made at low temperature, in a gastight state and ... transformation in rats J Pharm Sci 74:780–782 10) Kielbasa WB, Bauer JA, Fung HL (1999) Analysis of isobutyl nitrite inhalant in rat and human blood: application for pharmacokinetic investigations J Chromatogr ... concentration of an alkyl nitrite on the horizontal axis and peak area on the vertical axis The concentration of the analyte in a specimen is calculated using the calibration curve i Assessment and some...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)
... GC/MS analysis for DAEMS in serum (a) a total ion chromatogram (TIC) and a mass chromatogram; (b) an EI mass spectrum of DAEMS; (c) a CI mass spectrum of DAEMS Poisoning case, and toxic and fatal ... GC/MS analysis for EMPA in serum (a) a TIC and mass chromatograms; (b) an EI mass spectrum of the t-BDMS derivative of EMPA; (c) a CI mass spectrum of the same derivative of EMPA data of animals According ... concentrations of DAEMS are spiked into blank serum specimens containing a fixed amount of DAEMO (IS) each and extracted as described before Since the base peaks of DAEMS and DAEMO (IS) equally appear...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)
... 188 Cannabinoids and their metabolites GC analysis of cannabinoids in plant specimensa Reagents and their preparation • • • Extraction and purification of cannabinoids [3]: Cannabis sativa L is ... construct a calibration curve with cannabinoid concentration on the horizontal axis and with peak area ratio of a cannabinoid to IS on the vertical axis GC analysis of cannabinoids in plant specimens ... side-chain hydroxylated ∆6-tetrahydrocannabinol metabolites Acta Pharm Suec 16:21–33 9) Yamamoto I, Watanabe K, Narimatsu S et al (1990) A GC-MS method for determination of ∆9-tetrahydrocannabinol-11-oic...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)
... Main metabolic pathways of morphine, heroin and codeine The thick and thin arrows show the main and minor metabolic pathways, respectively ⊡ Figure 3.1 196 Morphine and its analogues GC and ... Qualitative analysis is made by the comparison of the retention time of a peak of a specimen with that of the authentic standard and also by the confirmation of the absence of such a peak in a ... morphine, codeine and tetrahydropapaveroline in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible biosynthetic pathway of morphine from L-3,4-dihydroxyphenylalanine...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)
... normal cyanosis headache, dyspnea, tachypnea, tachycardia and hypertension mental derangement, listlessness and metabolic acidosis coma, convulsive attack and hypotension death A poisoning case ... centrifugation at 3,000 rpm for min, 1- or 4- L of the upper layer is injected into GC Various known amounts of nitrate and a fixed amount of IS are added to blank specimens and processed in the same way ... of the oxidation of nitrite into nitrate and the same extractions as those for nitrate A calibration curve for nitrite using blank specimens and IS is also prepared for quantitation in the same...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)
... amanitin 473, 477, 479 amido-type local anesthetic 385 1-amino-4-phenylbutane 173 2-amino-6-hydroxymethyl8-hydroxyquinazoline 482 aminomethyl phosphonic acid 546 7-aminonitrazepam 19 5-aminoquinoline ... alminoprofen 325, 330, 332 alprazolam 284, 285, 290 alternative specimens Amanita neoovoidea 480 Amanita pantherina 469 Amanita phalloides 469 Amanita verna 469, 474 Amanita virosa 469, 473 amanitin ... N-chloromethylphthalimide 327 N-de-ethyl-LSD 228 n-decane 165 n-heptane 165 n-hexane 165 N-methyl- 1-( 3,4-methylenedioxyphenyl )-2 -butanamine 229 N-methyl- 1-( 3,4-methylenedioxyphenyl )-3 -butanamine 233 N-methyl-bis(trifluoroacetamide)...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)
... shows mass spectra of the authentic cocaine, EME and BE after derivatization Setting up of cutoff values are very common in USA and Europe as a part of QC (quality control) and QA (quality assurance) ... Significance and problems of doping tests and toxin analysis Nipponrinsho 57:361–363 (in Japanese) 10) Sander R, Ryser MA, Lamoreaux TC et al (1985) An epidemic of cocaine associated deaths in Utah ... and death In addition, the ratios of cocaine to BE in blood and in the brain, and the brain-to-blood ratios of cocaine and BE were compared with those described in literature [11]; such comparison...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)
... concentration in the horizontal axis and peak area ratio of pentazocine to IS in the vertical axis The peak area ratio of a test specimen is applied to the calibration curve to obtain its pentazocine ... bring its pH to about A 10-mL volume of ethanol and 10 mL distilled water are passed through a Sep-Pak C18 cartridge using a 10-mL volume glass syringe to activate the cartridge at a flow rate ... (17) 285 (9) Poisoning case, and toxic and fatal concentrations A 17-year-old female [11] ingested about 100 tablets of pentazocine (total amount estimated, 2.5 g) and fell into unconsciousness...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)
... blood and urine, because its amount to be ingested is as small as about 10 µg and LSD is rapidly metabolized in human bodies As metabolites of LSD, 2-oxo-LSD, 3-, 1 3- and 14-hydroxy-LSDs and an N-de-ethyl-LSD ... Jiho Inc., Tokyo, pp 108–109 (in Japanese) 2) The Pharmaceutical Society of Japan (ed) (1992) Standard Methods of Chemical Analysis in Poisoning – With Commentary – Nanzando, Tokyo, p 43 and p ... N-de-ethyl-LSD are known [3] After oral ingestion of 160 µg LSD, the maximum blood concentration of LSD was ng/mL and its half-life is said to be about h The concentrations of LSD of LSD-abusing...
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