43319 santa claus is coming to town (1)

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... of gene expression As each step of the RNA metabolism is tightly regulated, the regulation of mRNA export, stability and translation rate is essential for the control of the expression of mRNAs ... localized in the UTRs of the transcript and the trans-acting factors (RNA-binding proteins and noncoding regulatory RNAs) that bind to these sequences Among the best studied regulatory sequences, the ... of the reporter protein fused with the full-length ASF ⁄ SF2 protein, or with the RRM1 alone Most likely, this difference is partly a result of the absence of the RS domain that contributes to...
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Báo cáo y học: "b-TrCP is dispensable for Vpu’s ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release" pot

Báo cáo y học:
... reflect distinct molecular scenarios (see Discussion) To exclude the influence of a potential compensatory functional redundancy of the two b-TrCP isoforms in cells in which only one of the isoforms ... CD317 at the TGN by direct or indirect mechanisms Despite increasing insight into the molecular mechanisms underlying Vpu’s ability to overcome the CD317mediated virion release restriction, key aspects ... leaves display potent anti -HIV-1 activity by increasing the virion density Retrovirology 2008, 5:27 Ishikawa J, Kaisho T, Tomizawa H, Lee BO, Kobune Y, Inazawa J, Oritani K, Itoh M, Ochi T, Ishihara...
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Báo cáo y học: "The HIV-1 Rev/RRE system is required for HIV-1 5’ UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particle" ppsx

Báo cáo y học:
... (including 5’ UTR cis elements, nucleocapsid, and Rev/RRE system) ; iv) the Rev/RRE system and 5’ UTR cis elements synergize to increase vector titers that rival those of HIV-1 derived vectors; and v) HIV-1 ... MLV GFP Cytoplasmic RNA Viral Particle RNA Figure HIV-1 Rev/RRE and cis elements in the 5 UTR cooperatively enhance RNA encapsidation into HIV-1 viral particles A Vector RNA was measured by qRT-PCR ... vector system was used to examine if the HIV-1 Rev/RRE and 5’ UTR cis elements can mediate packaging of RNA into MLV viral particles, thereby resulting in a loss of specificity for HIV-1 viral...
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Báo cáo y học: "Endogenous TGF-β activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells" docx

Báo cáo y học:
... cytosol to initiate cell death The late apoptotic and/ or dead cells may release ROS into the cultures to activate latent TGF-β [34,35] Indeed, the apoptotic T cells in the TCR- and CD28treated ... includes induction of Foxp3 and regulatory T cells As a critical step in this process, the ROS produced by TCR-activated T cells plays a significant role in converting the latent TGF-β into the ... Since TGF-β has been implicated in the induction of Tregs in murine cells, we set out to investigate whether TGF-β has a role in the unexpected induction of Tregs by TCR stimulation in human T cells...
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Báo cáo y học: "The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G" ppsx

Báo cáo y học:
... Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions Retrovirology 2007, 4:48 Liu B, Yu X, Luo K, Yu Y, Yu XF: Influence of primate lentiviral Vif ... required for HIV-1 infectivity in nonpermissive cells Co-expression of Vif and hA3G were necessary for a robust suppression of viral infectivity by the peptide A novel finding in this study is ... second histograms) due to the ability of Vif to suppress the antiviral activity of hA3G However, treatment of these producer cells with Peptide significantly suppressed the infectivity of +Vif virus...
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Báo cáo y học: " Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks" potx

Báo cáo y học:
... susceptibility to HIV-1 infection [11] Here we extended our investigations of the mechanisms underlying HIV-1 restriction in CD4 T cells and found that both entry and post -entry steps of HIV-1 replication ... remain uninfected (exposed uninfected individuals, EU) are likely to be naturally resistant to infection Relative resistance of CD4 T cells and/ or macrophages to HIV1 infection has been reported in ... of the in vitro resistance mechanisms described here may contribute to protection against HIV-1 infection in exposed uninfected Vietnamese individuals, possibly in conjunction with other innate...
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Báo cáo y học: " Protein methylation is required to maintain optimal HIV-1 infectivity" ppsx

Báo cáo y học:
... when HIV-1 Env was replaced by VSV-G One possibility is that HIV-1 Env methylation might contribute towards virus infectivity, although it is equally plausible that an endosomal entry pathway bypassed ... membrane -protein methylation in hereditary spherocytosis A marker of cytoskeletal disarray European Journal of Biochemistry 1995, 228(3):894-898 Manna C, Hermanowicz N, Ro JY, Neilan B, Glushko ... Alterations of protein methylation have been linked to several disease states including idiopathic pulmonary http://www.retrovirology.com/content/3/1/92 arterial hypertension, hereditary spherocytosis [24],...
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It is said that he is said to , v v và supposed to (1)

It is said that       he is said to   , v v   và supposed to (1)
... It is said that / He is said to , v. v Supposed to = The strike is expected to begin tomorrow (Người ta cho đình công bắt đầu v o ngày mai) - It is alleged to have stolen $60 = He is alleged ... gặp Tom) 2/3 It is said that / He is said to , v. v Supposed to - The train was supposed to arrive at 11.30 but it was 40 minutes late (The train should have arrived at 11.30 according to the ... It s supposed to be very good (= It is said to be very good; people say that it s very good) (Chúng ta xem phim Người ta nói phim hay lắm) - He is supposed to have stolen $60 ( =He is said to have...
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