403 song across the universe by fiona apple

Báo cáo khoa học: Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane potx

Báo cáo khoa học: Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane potx
... the anesthetics benzyl alcohol, propofol, chloroform and diethyl ether reversed the resistance by acceleration of the passive transport of the drug or dye across the plasma membrane At these concentrations, ... concentrations, the anesthetics further enhanced the rate of passive drug permeation and interfered with the active export of the drug by Pgp Effect of modulators on the efflux of the rhodamine ... anesthetic-mediated acceleration of transbilayer drug movement is due either to enhanced rate of drug flip-flop across the lipid core of the membranes or to greater affinity of the drugs for the plasma membrane...
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báo cáo hóa học: " Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF" potx

báo cáo hóa học:
... Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the bloodbrain barrier is mediated by luminal microvessel IL-6 and GM-CSF 1,2,3 Shinya Dohgu 2,3,4 , Melissa A Fleegal-DeMotta ... permeability of the BMEC monolayer as measured by TEER is not mediated by extracellular IL-6 and GM-CSF We further investigated this functional polarity by adding IL-6 and GM-CSF to the luminal or abluminal ... whether IL-6 and GM-CSF release from BMEC by LPS mediated these effects The presence of LPS and antibodies to IL-6 or GM-CSF in the 15 luminal chamber attenuated LPS-enhanced HIV-1 transport across...
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Báo cáo hóa học: " Evaluation of the nanotube intrinsic resistance across the tip-carbon nanotube-metal substrate junction by Atomic Force Microscopy" pptx

Báo cáo hóa học:
... Cite this article as: Dominiczak et al.: Evaluation of the nanotube intrinsic resistance across the tip-carbon nanotube- metal substrate junction by Atomic Force Microscopy Nanoscale Research Letters ... CNT -substrate R substrate Figure (a) Schematic view of the AFM tip and the «tip-CNT -substrate junction A bias voltage V is applied between the tip and the substrate, the arrows represent the ... between the tip and the substrate, supplies the two junctions in series tip-CNT and CNT -substrate The CNT -substrate interface is supposed to be formed by a number of elementary contacts at the top of...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_1 pot

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_1 pot
... burst out: “It’s the products The products SUCK! There’s no sex in them anymore.”1 The Fall of Apple Apple’s fall was quick and dramatic In 1994, Apple commanded nearly 10 percent of the worldwide ... experience from the TV ads that stimulate desire for Apple s products, to the museum-like retail stores where customers buy them; from the easy-touse software that runs the iPhone, to the online ... the money,” Jobs said Wozniak was the hardware genius, the chip-head engineer, but Jobs understood the whole package Thanks to Jobs’s ideas about design and advertising, the Apple II became the...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_2 potx

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_2 potx
... to bring the Apple people around and sell the deal.” 16 The Brand Jobs realized that while the products sucked, the Apple brand was still great He considered the Apple brand as one of the core ... another The killing of the Newton was widely considered an act of vengeance on a previous Apple CEO, John Sculley, who had ousted Jobs from Apple in the late 1980s The Newton was Sculley’s baby, ... anywhere If they continued to buy Apple s machines, they were a great foundation for a comeback The Clones Jobs killed the clone business The move was highly controversial, even inside the company,...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_3 pdf

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_3 pdf
... for Steve Jobs is the right hemisphere talks to the left hemisphere.”11 Lessons from Steve • Be a despot Someone’s got to make the call Jobs is Apple s one -man focus group It’s not how other ... on another machine that was placed next to the Director demo When they showed the working code to Jobs, he’d lean forward, his nose to the screen, and examine them closely, moving from the demo ... attract great games From the Mac to the Palm Pilot and the Xbox, the success of a platform is primarily determined by the software that can run on it In some cases this is the socalled killer...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_6 docx

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_6 docx
... celebrating the misfits, the rebels, the troublemakers the crazy ones.” The people who are crazy enough to think they can change the world are the ones that do,” the ad proclaimed The commercial ... Apple has led the world in industrial design His partners at Apple include Jon Rubinstein, who oversaw a string of hit hardware, from the iMac to the iPod; and Ron Johnson, who masterminded Apple s ... late-night comedy shows, then the ads have graduated from the commercial to the cultural realm Jobs’s association with the ad company began in the early 1980s, when the agency—then known as Chiat/Day—...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_7 doc

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_7 doc
... the people who report to him, Apple s middle managers demand the same level of high performance from their staff The result is a reign of terror Everyone is in constant fear of losing their jobs ... to work there,” said Eigerman “They are very excited to be there There’s a lot of passion People love the products They really believe in the products They are very excited about what they are ... believe Apple s chutzpah and thought the company had stepped over the line In Apple s defense, Clow told the New York Times that Apple intended to honor the subjects of the campaign, not exploit them...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_8 pdf

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_8 pdf
... with Jobs, he’d take off his leather shoes and put on the sneakers Steve is a militant vegan,” the source explained Inside the company, Jobs is known simply as Steve or "S.J.” Anyone else whose ... Anyone else whose name is Steve is known by their first and last names At Apple, there is only one Steve There are also F.O.S.—Friends Of Steve persons of importance who are to be treated with ... phenomenon, it comes from many places, but much of it is informed by Jobs’s careful attention From the scroll wheel on the iPod to the box the iPod comes in, Jobs is alert to every aspect of the customer...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_9 ppt

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_9 ppt
... focus Who usually ends up running the show?” asked Jobs The sales guy.”12 Jobs cited as a good example Steve Ballmer at Microsoft, the company’s chief salesman who took over from Bill Gates, the ... you can take business from is yourself?” Jobs said in situations like this, the people who built the company in the first place— the product-oriented staffers—tend to become replaced by those with ... that period “It’s the marketing guys or the ones who expand the business into Latin America or whatever Because what’s the point of focusing on making the product even better when the only company...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_10 pot

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_10 pot
... even knew of the existence of the iPod project To complete the project as quickly as possible, the team took as many parts as possible off -the- shelf: the drive from Toshiba, a battery from Sony, ... details, after the executive team The graphics department, for example, was one of the first groups inside Apple to learn the iPod’s name, so that it could prepare the packaging The other groups ... uncompromising focus on the customer experience Lessons from Steve • Don’t lose sight of the customer The Cube bombed because it was built for designers, not customers • Study the market and the industry...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_11 pptx

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_11 pptx
... believes that Apple needs to wrest control of the devices partly from the consumer The iPod is a good example The complexities of managing an MP3 player are hidden from the consumer by having iTunes ... and the Xbox at the heart of Microsoft’s own “digital hub.” Controlling the whole widget may have been the wrong model for the last thirty years, but it is the right model for the next thirty the ... error • Embrace the team The iPod doesn’t have a sole progenitor: there’s no single “Podfather.” It’s never just one person— success always has many fathers Chapter Total Control: The Whole Widget...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_13 ppt

Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_13 ppt
... quality, approach to quits Apple ( ) reorganization of Apple ( ) returns to Apple ( ) secrecy whole systems approach See also Apple Inc.; individual topics Johnson, Ron, Apple Stores Joswiak, Greg ... Gregory Mandich, Mitch Manock, Jerry Manovich, David Manufacturing overseas and product design Marketing Macworld Expo product reviewers and secrecy as theater Mercer, Paul Microsoft Apple innovations, ... process iWeb Jobs, Steve Apple as reflection of biographical information business- related weaknesses cancer charisma/reality distortion field as control freak detail orientation of focus at Apple getting...
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