39943 conditional type i

Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx

Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx
... successively The < /b> immunoreactive bands were visualized using diaminobenzidine (DAB) (Boster Biological Technology, Wuhan, Hubei, China) The < /b> following antibodies were used: rabbit SRBI polyclonal antibody ... (PAK1) inhibition of < /b> the < /b> human scavenger < /b> receptor < /b> class < /b> B, type I promoter in macrophages is independent of < /b> PAK1 kinase activity, but requires the < /b> GTPase-binding domain J Biol Chem 276, 46< /b> 807 46< /b> 8 14 < /b> ... et al Fig DNA binding activity and transcription activity of < /b> KLF4 to the < /b> KLF binding element of < /b> hSR-BI promoter in PMA-differentiated THP-1 macrophages (A) Binding activity of < /b> KLF4 to the < /b> corresponding...
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Tài liệu Báo cáo khoa học: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor pptx

Tài liệu Báo cáo khoa học: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor pptx
... immunoprecipitated with an anti -FGFR3 serum then immunoblotted with anti-ubiquitin and anti -FGFR3 sera (D) Disabling the c-Cbl ubiquitylating activity does not affect the ubiquitylation of the wild -type, ... proteasome and lysosome inhibitors on ubiquitylation of wild -type and mutant FGFR3 (A) Ubiquitylation of wild -type and Y373C FGFR3 in the absence or presence of the proteasome inhibitor MG132 (50 lM ... with chloroquine as indicated Lysates were immunoprecipitated and processed for immunoblotting with anti-ubiquitin and anti -FGFR3 sera (C) Ubiquitylation of the wild -type receptor is increased by...
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Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf

Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf
... protein, additional information about post-translational modifications, like 2895 Signal peptidase I activity in M pneumoniae Fig SIGNAL P predicted and experimentally verified cleavage site for P40 ... N-terminal part of the peptide, it is evident that the N-terminal amino acid is asparagine (position 26), but increased in mass by 136 Da Because this modification is only possible at the free a amino ... although a SPase I activity has been shown to be essential for cell viability in all bacteria analyzed [26] To test experimentally whether there is a type I SPase activity in M pneumoniae, we determined...
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Tài liệu Báo cáo khoa học: Type I antifreeze proteins expressed in snailfish skin are identical to their plasma counterparts doc

Tài liệu Báo cáo khoa học: Type I antifreeze proteins expressed in snailfish skin are identical to their plasma counterparts doc
... Expression of snailfish type I AFPs in skin tissue A B C D Fig Distribution of type I AFP mRNA in skin and liver tissues from Atlantic and dusky snailfish (A) Northern blot analysis of skin tissue ... expression only in skin tissue Taken together, the evidence indicates that the circulating plasma AFPs and skin localized AFPs are identical proteins that are normally expressed by the same skin- specific ... transcripts produce proteins that are identical to their corresponding plasma proteins Results cDNA library screening and cloning of snailfish skin AFP A cDNA library was constructed to investigate the...
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Tài liệu Báo cáo khoa học: Identi®cation and properties of type I-signal peptidases of Bacillus amyloliquefaciens doc

Tài liệu Báo cáo khoa học: Identi®cation and properties of type I-signal peptidases of Bacillus amyloliquefaciens doc
... Cloning of sipU Cloning of sipU Cloning of sipU Cloning of sipU Cloning of sipU Cloning of sipU Cloning of sipU Cloning of sipU Cloning of sipV Cloning of sipV Cloning of sipV Cloning of sipV ... Cloning of sipV Cloning of sipV Cloning of sipV Construction of pOpacVh Construction of pOpacVh Cloning of sipW Cloning of sipW Cloning of sipW Cloning of sipW Cloning of sipW Cloning of sipW ... Construction of pOpacWh Construction of pOpacWh Construction of pOpacSh Construction of pOpacSh Construction of pOpacTh Construction of pOpacTh Construction of pOpacBh Construction of pOpacBh Construction...
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Báo cáo khoa học: Enzymatic investigation of the Staphylococcus aureus type I signal peptidase SpsB – implications for the search for novel antibiotics ppt

Báo cáo khoa học: Enzymatic investigation of the Staphylococcus aureus type I signal peptidase SpsB – implications for the search for novel antibiotics ppt
... in the presence of inhibitor, v0 is the initial velocity in the absence of inhibitor but with (2%) dimethylsulfoxide The IC50 value was determined by tting the percent inhibition versus inhibitor ... substrate binding [17], highlighting their signicance In SpsB, it is also likely that one or more of the amino acids immediately preceding the catalytic serine form a part of the substrate-binding pocket ... essentiality, the easier accessibility of the catalytic domain for potential inhibitors as a result of being located on the outer side of the cytoplasmic membrane, and the different catalytic mechanism...
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Báo cáo khoa học: Involvement of lysine 1047 in type I collagen-mediated activation of polymorphonuclear neutrophils doc

Báo cáo khoa học: Involvement of lysine 1047 in type I collagen-mediated activation of polymorphonuclear neutrophils doc
... (contained within the cyclic peptide CTRKKHDNAQC derived from jararhagin disintegrin) is essential for binding to the I domain of a2 integrins [24] Similarly, members of the lysine threonine–serine ... oxidase-hypoxanthine system (data not shown) These results suggested the involvement of lysine- containing sequences in the activation mechanism Involvement of lysine residues contained within a1CB6 peptides In ... A, Wiman B & Pap S (2003) Identification of amino acids in antiplasmin involved in its noncovalent lysine- binding-site’-dependent interaction with plasmin Eur J Biochem 270, 2023–2029 Panizzi P,...
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Báo cáo khoa học: Promoters of type I interferon genes from Atlantic salmon contain two main regulatory regions docx

Báo cáo khoa học: Promoters of type I interferon genes from Atlantic salmon contain two main regulatory regions docx
... role in the activation of the salmon IFN promoter, but it cannot act alone to initiate transcription A hallmark of mammalian IFN-a ⁄ b is their rapid induction by virus infection mainly because of ... Atlantic salmon A role for NFjB in the activation of PR -I was further supported by two different inhibitor experiments First, dose-dependent inhibition of promoter activity by the NFjB inhibitor ... type I IFN genes of Atlantic salmon show a rather unique organization of the promoter in comparison with mammals, 3894 birds and zebrafish Atlantic salmon stimulated with the dsRNA polyinosinic...
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Báo cáo khoa học: Differential interactions of decorin and decorin mutants with type I and type VI collagens pptx

Báo cáo khoa học: Differential interactions of decorin and decorin mutants with type I and type VI collagens pptx
... was higher than that of the dimeric complex of decorin with type I or type VI collagen The existence of an interaction of decorin with type I and type VI collagen has been shown in vivo in skin ... chips and with 0.3 M NaCl in the case of immobilized type VI collagen To form a complex consisting of decorin, type I and type VI collagen, type VI collagen was first immobilized After binding of ... glycosaminoglycan chain; type I collagen, black circle; type VI collagen, white cylinder (A) Interaction involving dimerization of decorin and binding of both collagens to the inner surface of decorin...
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