32922 quiz breaking the ice activity

Cambridge - The grammar activity book (bob obee)

Cambridge - The grammar activity book (bob obee)
... in the United Kingdom at the University Press, Cambridge ISBN 521 575796 The Grammar Activity Book Map of the book KEY : E=ELEMENTARY; P=PRE-INTERMEDIATE; I=INTERMEDIATE; U=UPPER-INTERMEDIATE Activity ... Road, Oakleigh, Melbourne 3166, Australia © Cambridge University Press, 1999 The pages in this book marked ‘From The Grammar Activity Book by Bob Obee © Cambridge University Press 1999 P H O T O ... PUBLISHED BY THE PRESS SYNDICATE OF THE UNIVERSITY OF CAMBRIDGE The Pitt Building, Trumpington Street, Cambridge CB2 1RP, United Kingdom CAMBRIDGE UNIVERSITY PRESS The Edinburgh Building, Cambridge...
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the ICE - An integrated solution

the ICE - An integrated solution
... the flag and grabs the emulator Next, they try to find Joe or Susan — the one or two engineers in the place who actually know how to use it — and hope they can find and fix the problem The other ... for a week now, and they’ve finally thrown in the towel and want to bring in the big gun Up to now, they’ve resisted the urge to get the ICE because they figured it would take them the better part ... would want to set the trigger point so that the trigger point occurs in the middle of the trace buffer In this way, you can see all of the states of the system leading up to the failure and then...
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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... there could be a link between EGF-induced reduction in Bid and tBid levels and the ubiquitin ligase activity of Itch In this study, we first examined the ability of Itch to interact with Bid and ... proteins Bim and Bak and the C-terminal fragment of Bid The ubiquitin ligases responsible for the ubiquitylation are in most cases not known [44] Here, we have identified Itch as the ubiquitin ligase ... Azakir et al Itch promotes tBid degradation Fig tBid, the active, apoptotic form of Bid, interacts with the ubiquitin ligase Itch, which leads to its degradation and proteasomedependent degradation...
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Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf

Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf
... effect on the chaperone activity of aB-crystallin against the DTT-induced aggregation and precipitation of insulin B C Fig aB-crystallin protects against the DTT-induced aggregation of insulin, ... increased the chaperone activity of aB-crystallin (84 ± 4%) against this target protein The effect of Arg-HCl on the structure and assembly of aB-crystallin We investigated whether the effects of these ... on the overall activity of chaperone proteins Of the target proteins tested, Arg-HCl was found to specifically increase the activity of aB-crystallin against DTT-induced precipitation of insulin...
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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
... geometry of the hinge loop after ligation Also in this case no clashes were detected at Electrostatic interactions and antitumor RNases the dimer interface of the models or in the surroundings of the ... the C-terminal and N-terminal structural regions, respectively, of the two A and B monomers of the dimeric RNase The black circle between the monomers indicates the mass center of the dimer Electrostatic ... Electrostatic interactions and antitumor RNases r ¼ 180° and i ¼ 90° In this orientation, characterized by the strongest electrostatic attraction of the RNases with the membrane, all RNases pointed their...
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Tài liệu Báo cáo khoa học: Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3 pdf

Tài liệu Báo cáo khoa học: Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3 pdf
... mixture of enzyme and oxidized elafin, NE and Pr3 are inhibited to the extent of 25% and 10%, respectively This clearly shows that oxidized elafin is a poor inhibitor of the elastolytic activity of these ... of dissociation of 36 –105 [15] The oxidation of elafin and trappin down-shifts the half-life of there complexes with NE to % 1 .3 1.8 On the other hand, the oxidized inhibitor–Pr3 complexes are ... oxidation of M51 and M89 of M25L elafin and M63L trappin, respectively On the other hand, oxidation of M25L elafin and M63L trappin did not significantly affect their Ki for NE (Table 2) We therefore...
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Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx

Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... IMAGEQUANT software, and depurination was calculated by relating the amounts of the small aniline-fragment and 5.8S rRNA and expressing values as a percentage Reassociation and quantification of ... carried out for each individual atom Data collection and refinement statistics are given in Table Assay of the N-glycosidase activity of ricin A chain variants The activity of each of the RTA ... To assess the effect of substitutions made at each of the arginyl residues on catalytic activity of RTA, the ability of each of the purified RTA variants to depurinate yeast ribosomes was compared...
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Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx

Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx
... Mapping of ATP and pNPP binding sites of the Na pump (Eur J Biochem 271) 3933 Table Comparison of the primary structures of isoforms of Na+/K+ ATPase and H+/K+ ATPase in the range of the binding site ... and its position in the binding site was optimized Results Effects of truncation of the cytoplasmic H4-H5 loop of the a subunit of Na+/K+ ATPase on TNP -ATP binding and p-nitrophenylphosphatase activity ... 7.4 Binding of FITC was determined as the molar ratio of FITC bound per H4-H5 loop or per the a subunit of Na+/K+ ATPase [17] K+ activated phosphatase activity of the ATPase as well as the phosphatase...
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Tài liệu Báo cáo khoa học:Symmetric fluoro-substituted diol-based HIV protease inhibitors Ortho-fluorinated and meta-fluorinated P1/P1¢-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyy docx

Tài liệu Báo cáo khoa học:Symmetric fluoro-substituted diol-based HIV protease inhibitors Ortho-fluorinated and meta-fluorinated P1/P1¢-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyy docx
... difluoro-substitutions at the ortho and meta positions on P1/P1¢-benzyloxy side groups of symmetric diol-based protease inhibitors preserve the binding efficacy and significantly improve the antiviral potency ... inhibitors complexed to HIV protease Compared with the nonsubstituted analog, the fluoro inhibitors have improved the antiviral activity and retained the binding efficacy The flexibility of the target molecule ... the P1/P1¢ side groups and residue side- chain adaptations In Fig inhibitors and are superimposed on to the nonsubstituted analog to show the difference in position of the benzyloxy side groups associated...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc

Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
... between the base adenine (or hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, ... Regulation of calcium signalling by the second messenger cyclic adenosine diphosphoribose (cADPR) Curr Mol Medical 4, 239–248 16 Guse AH (2004) Biochemistry, biology, and pharmacology of cyclic adenosine ... situation is unique for the northern ribose since replacement of the oxygen by a carbocyclic bridge in the southern ribose in the molecule termed cyclic aristeromycin diphosphoribose (cArisDPR,...
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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx
... suppression of respiration during hypoxia In the absence of differential regulation of a speci c nuclear gene coding for the subunits of CytOX, changes in the microenvironment of the cell may induce alterations ... modulates the expression of mRNAs for CytOX subunits and also the catalytic activity of the enzyme complex Our results show that the levels of some of the select mitochondrial and nuclear genome encoded ... genes CYC1 and CYC7, which encode iso-1 and iso-2 of yeast cytochrome c, respectively CytOX 5a and CYC1 are coexpressed under aerobic conditions (O2 > 0.5 lM), whereas CytOX 5b and CYC7 are co-expressed...
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Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt

Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
... a monoclonal anti-porphyrin Ig, with an iron( III)-DoCPP cofactor and imidazole as an axial ligand of the iron which, respectively, mimick the heme cofactor and the axial histidine ligand of the ... Binding of imidazoles to the iron( III) of Fe(ToCPP) and Fe(ToCPP))13G10 The second part of our results concerns the binding of imidazole derivatives on the iron of Fe(ToCPP) either alone in solution ... binding of ligands on the iron of Fe(porphyrin))13G10 complexes: (A) binding of H2O2 on the iron of 13G10-(Fe(ToCPP), (B) binding of two CN± ligands on the iron of 13G10-(Fe(ToCPP), (C) binding of...
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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc
... within )260/)119, we Ó FEBS 2002 Integrin a3 gene promoter (Eur J Biochem 269) 4529 Fig Effects of mutations in the Ets- and GATA-binding sites and the E-box of the mouse a3 integrin gene on promoter ... assay (EMSA) using the Ets consensus site at )133 As the involvement of the Ets consensus binding site at )133 in the promoter activity of the mouse a3 integrin gene was suggested by the luciferase ... regulation for the integrin a3 subunit is one of crucial issues to be resolved in cancer biology We previously reported the structures of the mouse a3 integrin subunit gene including the exon/intron...
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Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx

Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx
... mutations at these positions in Sendai should promote instability of the surface region As the C region of Sendai also would play an important role in restraining the conformational change of the surface ... temperature indicates the stability of the structure of the protein The difference of the increments between the inactive temperature and the Tm should indicate that the mutations improved the stability ... original activity after h and h of incubation, respectively The stability of Y269A/A271T/Q272R- and Y269A-ALP I in alkaline Ó FEBS 2002 The molecular surface in enzymatic stability in extraordinary environments...
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