Accurate results in the clinical laboratory 2013

Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx

Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx
... resulting in the accumulation of both unmodified cholesteryl esters and glycated apoB in the cells The rate of removal of the latter species is slow, with only 20–30% of the glycated protein being ... although the concentrations of these materials present in the artery wall, and in atherosclerotic lesions, are unknown The role of glycation and the two facets of glycoxidation in generating modified ... Klein RL & Virella G (1996) Modification of lipoproteins in diabetes Diabetes Metab Rev 12, 69–90 10 Tomkin GH & Owens D (2001) Abnormalities in apo B-containing lipoproteins in diabetes and atherosclerosis...
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Exploring Challenges, Progress, and New Models for ENGAGING THE PUBLIC in the CLINICAL RESEARCH ENTERPRISE Clinical Research Roundtable Workshop Summary pot

Exploring Challenges, Progress, and New Models for ENGAGING THE PUBLIC in the CLINICAL RESEARCH ENTERPRISE Clinical Research Roundtable Workshop Summary pot
... Exploring Challenges, Progress, and New Models for ENGAGING THE PUBLIC in the CLINICAL RESEARCH ENTERPRISE Clinical Research Roundtable Workshop Summary Based on a Workshop of the Clinical Research ... Contents Foreword ix Workshop Summary 1 Priorities for Engaging the Public in the Clinical Research Enterprise Workshop Introduction, Priorities for Engaging the Public, Key Issues Facing the Clinical ... Biographies C Background for CRR Workshop: Exploring New Models for Engaging the Public in the Clinical Research Enterprise D Voluntary Health Agencies and the Clinical Research Enterprise: Exploratory...
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báo cáo hóa học:" Trends in the clinical characteristics of HIVinfected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009" pdf

báo cáo hóa học:
... characteristics of patients accessing ART during this phase of the scale up in east Africa Methods Patients The EA-IeDEA is a cohort of patients from clinical care sites in Uganda, Kenya and Tanzania ... comprised a decreasing fraction of new patients accessing ART in Kenya, dropping from 41% in 2002- 03 to 34% in 2008-09 (p < 0.01), but the fraction of men accessing care in Uganda and Tanzania did ... were from Uganda, and 4119 (9%) were from Tanzania Of 35 sites, 28 were in Kenya, four in Uganda and three in Tanzania Overall, 1118 (2%) patients started ART in 2002- 03, 12, 875 (27%) in 2004-05,...
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Quality and Risk Management in the IVF Laboratory pdf

Quality and Risk Management in the IVF Laboratory pdf
... especially in the developed world Quality and Risk Management in the IVF Laboratory As a result of this global expansion and commercialization, quality management and risk management are becoming increasingly ... scheme for IVF clinics has recently been introduced as a joint venture between the CCHSA and the Canadian Fertility and Andrology Society (CFAS) 14 Quality and Risk Management in the IVF Laboratory ... success within or years TQM in IVF can be seen as encompassing the following areas of a Center’s operation, all of which impinge upon the laboratory 32 Quality and Risk Management in the IVF Laboratory...
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Báo cáo y học: "Developments in the clinical understanding of osteoarthritis" docx

Báo cáo y học:
... provided new insights into how OA may be successfully managed The symptoms of osteoarthritis: pain and instability The pain of OA is activity-related, with pain coming on generally only when a person ... ligaments especially near their insertions, in bone, in muscle, and in the outer third of the meniscus in the knee In an unusual study in which the lead investigator became the study subject and underwent ... not the only symptom of OA experienced by patients with knee and hip OA They also frequently experience a sensation of instability or buckling The most common symptom is one of shifting or instability...
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Báo cáo y học: "Developments in the clinical understanding of rheumatoid arthritis" ppt

Báo cáo y học:
... ultimately, of the upregulation of proinflammatory cytokines [19,20] By whichever means they themselves become activated, they induce a plethora of inflammatory products, including degradative enzymes, ... attained under therapy, the lower the progression of joint damage [12,22] On the other hand, in clinical practice and clinical trials, response to or improvement of therapy has been the center of ... mediate most if not all of the total phenotypic expression of RA, including joint destruction The fact that CRP is induced by the proinflammatory cytokine interleukin-6 (IL-6) and the observation that...
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Báo cáo y học: "Developments in the clinical understanding of lupus" pot

Báo cáo y học:
... by type I IFN A randomized placebo-controlled study of the withdrawal of hydroxychloroquine treatment in clinically stable SLE patients was published in 1991 by the Canadian Hydroxychloroquine ... pathophysiology through their capacity to focus relevant antigens for presentation to T cells, by production of cytokines, through their role in organizing the anatomy of the germinal centers and other ... at the 2008 ACR meeting Neither primary nor secondary endpoints were achieved Active debate in the clinical research community has included the possibility that prednisone, administered early in...
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A Primer on Quality in the Analytical Laboratory potx

A Primer on Quality in the Analytical Laboratory potx
... as the Food and Drug Administration In these cases, the analytical laboratory is one component of many that plays a part in a total quality scheme, or Total Quality Management, TQM TQM is a concept ... tank of liquid sugar solution used in a pharmaceutical preparation into the analytical laboratory for analysis The small portion of the solution, perhaps a small vial, that is obtained for the ... is global For this reason, an international standards organization governing global quality has been created It is called the International Organization for Standardization or ISO, and is a worldwide...
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Báo cáo y học: "Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat" pdf

Báo cáo y học:
... content of rat lungs Hydroxyproline content of rat lungs There was no significant difference in the hydroxyproline content of the four groups at days after instillation The hydroxyproline content of ... obviously by Lv-shCD36 Accordingly, CD36 may participate in the activation process of L-TGFβ1 in the early phase of the experimental silicosis Furthermore, silencing expression of CD36 prevented the ... activation by Lv-shCD36 in BALF The activation of L-TGF-β1 was determined by detecting the quantity of TGF-β1 in BALF using the CCL-64 growth inhibition assay The quantities of total TGF-β1 and active...
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Báo cáo khoa học: "Application of the Italian version of the Intensive Care Unit Memory tool in the clinical setting" ppsx

Báo cáo khoa học:
... intensive care Intensive Care Med 2002, 28: 38-43 Jones C, Humphris G, Griffiths RD: Preliminary validation of the ICUM tool for assessing memory of the intensive care experience Clin Intensive Care ... original, English language version of the instrument is available in full in the report by Jones and coworkers [10].) Analysis of the Intensive Care Unit Memory questionnaire To examine the extent ... administration Flow diagram of patient enrolment and questionnaire administration ICU, intensive care unit; ICUM, Intensive Care Memory (tool) was used in the study (see Appendix 1) (Note that the...
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Báo cáo y học: "Clinical review: Noninvasive ventilation in the clinical setting – experience from the past 10 year" pps

Báo cáo y học:
... with increasing physician experience Carlucci and coworkers [9] reported an 8-year retrospective study in which they investigated the changes in clinical practice of NIV in COPD patients In that ... suffering from COPD exacerbations to standard medical therapy alone or medical therapy combined with NIV Intubation and mortality rates in the NIV group were lower than in the conventional therapy ... NIV 100 The major advantages of NIV are related to the effects generated by the increase in intrathoracic pressure These benefits include increases in functional residual capacity and oxygenation,...
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Báo cáo khoa học: " Expression of cell surface receptors and oxidative metabolism modulation in the clinical continuum of sepsis" ppt

Báo cáo khoa học:
... the SOFA score Furthermore, we evaluated the cell surface expression previously [31] and the oxidative metabolism in monocytes In the present study, the expression of cell surface receptors and ... adhesion involves the interaction of leukocyte integrins of the beta subfamily (CD11a, CD11b and CD11c) with endothelial ligand receptors [19] An increase in the expression of those integrins on ... among the groups of patients and controls The expression of these integrins on neutrophils is clearly induced ex vivo upon LPS stimulation [38] In a clinical setting, Russwurm et al [20] found increased...
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Báo cáo y học: "Dose of dialysis in the intensive care unit: is the venom in the dose or in the clinical experience" pdf

Báo cáo y học:
... kidney injury patients than the dose of dialysis Finally, despite the previous seminal study [2] by the senior author of the paper by Vesconi and colleagues demonstrating that a ‘high’ dose of 35 ml/kg/h ... J, Hoy L, Haller H, Fliser D, Kielstein JT: The Hannover Dialysis Outcome Study: comparison of standard versus intensified extended dialysis for patients with acute kidney injury in the intensive ... number of dialysis days per week, targeting a Kt/V urea threshold However, as long as we know neither the nature nor the kinetics of many of the ‘toxins’ involved in the acute ‘uraemic syndrome’...
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