Design and Synthesis of Novel Benzodiazepines

Design and synthesis of novel metal complex protein conjugation agents for applications in bio imaging

Design and synthesis of novel metal complex protein conjugation agents for applications in bio imaging
... Design and Synthesis of novel metal complex- protein conjugation agents for Applications in bio- imaging WANG TAO (BSc, Sichuan University2008 ) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ... Modification of Proteins There is an increasing interest in protein conjugates for diagnosis and therapy Even though proteins often display limited pharmacokinetics, low proteolytic stabilities and the ... Design of biocompatible metal- complex protein conjugates In order to design biocompatible metal- complex protein conjugates which can achieveprecise intracellular delivery and improved sensitivity for...
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identification, design and synthesis of oxygenated hydrocarbon-based carbon dioxide-soluble polymers for chemical and petroleum engineering applications

identification, design and synthesis of oxygenated hydrocarbon-based carbon dioxide-soluble polymers for chemical and petroleum engineering applications
... ABSTRACT IDENTIFICATION, DESIGN AND SYNTHESIS OF OXYGENATED HYDROCARBON-BASED CO2-SOLUBLE POLYMERS FOR CHEMICAL AND PETROLEUM ENGINEERING APPLICATIONS Lei Hong, Ph.D University of Pittsburgh, 2006 ... defended on March 29, 2006 and approved by Dr Eric J Beckman, Professor, Chemical and Petroleum Engineering Department Dr J Karl Johnson, Professor, Chemical and Petroleum Engineering Department ... Professor, Department of Chemistry Dissertation Director: Dr Robert M Enick, Chairman and Professor, Chemical and Petroleum Engineering Department ii Copyright © by Lei Hong 2006 iii ABSTRACT IDENTIFICATION,...
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Design and synthesis of stimuli responsive polymer based nanoparticles

Design and synthesis of stimuli responsive polymer based nanoparticles
... of stimuli- responsive polymers are temperature -responsive polymers and pH -responsive polymers Other types of stimuli- responsive polymers, such as light -responsive polymers, field -responsive polymers ... methodologies for synthesis of stimuli- responsive polymers and the techniques for preparation of smart polymer based nanoparticles In Chapter 3, well-defined comb-like graft copolymers, consisting of a fluorescent ... images of the self-assembled hollow nanoparticles of the KVND copolymer of Table 3.1 in aqueous media: (a) pH and 25 oC, (b) pH and 25 oC and (c) pH and 40 oC The concentration of the copolymer...
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Design and synthesis of functional graphene composites and their applications

Design and synthesis of functional graphene composites and their applications
... DESIGN AND SYNTHESIS OF FUNCTIONAL GRAPHENE COMPOSITES AND THEIR APPLICATIONS JANARDHAN BALAPANURU M.Sc., University of Pune, India A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... bond of graphene and (b) formation of bond between organic functional groups and oxygenated-groups of GO (a) Addition of free radicals to sp2-carbon of graphene: Upon heating the mixture of diazonium ... functional graphene composites for various applications In this thesis, the design and synthesis of various graphene- based composites and their potential applications have been discussed with regards...
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Design and synthesis of donor acceptor hybridized small molecules and graphene derivatives for photovoltaic and optical studies

Design and synthesis of donor acceptor hybridized small molecules and graphene derivatives for photovoltaic and optical studies
... DESIGN AND SYNTHESIS OF DONOR ACCEPTOR HYBRIDIZED SMALL MOLECULES AND GRAPHENE DERIVATIVES FOR PHOTOVOLTAIC AND OPTICAL STUDIES ANUPAM MIDYA M.Sc (Chemistry), ... the interface of the donor and acceptor material and split into hole and electron For efficient charge separation, the HOMO and LUMO energy levels of p-type (Donor) and n-type (Acceptor) materials ... and formation of bonds (a) for two sp2 -hybridized carbon atoms Figure 1.2 A schematic diagram of energy levels, hybridization of atomic orbitals creates two continuous band states of filled and...
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Design and synthesis of cysmethynil and analogues as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT)

Design and synthesis of cysmethynil and analogues as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT)
... Wang M, Casey PJ Amino derivatives of indole as potent inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt) v TABLE OF CONTENTS ACKNOWLEDGEMENT .ii CONFERENCES AND PUBLICATIONS ... Analogues of cysmethynil demonstrate improved isoprenylcysteine carboxyl methyltransferase (Icmt) inhibition activity and antiproliferative activity in PC3 prostate cancer and MDA-MB-231 breast ... Gorla SK, Go ML, Wang M, Casey PJ Analogues of the Isoprenylcysteine Carboxylmethyltransferase Inhibitor Cysmethynil With Improved Antiproliferative Activity Against Breast and Prostate Cancer Cells...
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facile synthesis and characterization of novel nanocomposites

facile synthesis and characterization of novel nanocomposites
... To the best of our knowledge, this is the first time to observe this novel morphological structure of the nanocomposites of rutile nanocrystals and titanate nanotubes Fig XRD patterns of the starting ... large amount of water and hydroxyl groups existed in the tubular products because of the existence of a bending vibration of H O H at 1630 cm−1 , and a strong stretching vibration of O H Fig EDX ... reaction of bulky rutile powders and 10 M NaOH solution without using any templates and catalysts The inner and outer diameters of the nanotubes were approximately and nm, respectively The amount of...
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synthesis and characterization of novel ferromagnetic ppy-based nanocomposite

synthesis and characterization of novel ferromagnetic ppy-based nanocomposite
... Results and discussions The structures of the PPy/Zn0.5Cu0.5Fe2O4 nanocomposite were investigated by FTIR spectroscopy and X-ray diffraction FTIR spectra of the PPy and PPy/Zn0.5Cu0.5Fe2O4 nanocomposite ... XRD patterns of PPy/Zn0.5Cu0.5Fe2O4 nanocomposite (a) and the reference standard data for Zn0.5Cu0.5Fe2O4 of the JCPDS file No 77-0012 (b) Fig SEM micrographs of Zn0.5Cu0.5Fe2O4 (a) and PPy/Zn0.5Cu0.5Fe2O4 ... surface of Zn0.5Cu0.5Fe2O4 Fig shows the magnetic hysteresis loops of Zn0.5Cu0.5Fe2O4 and PPy/Zn0.5Cu0.5Fe2O4 nanocomposite at room temperature It can be observed that the saturation magnetization of...
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Báo cáo khoa học: Kinetic studies on endo-b-galactosidase by a novel colorimetric assay and synthesis of N -acetyllactosamine-repeating oligosaccharide b-glycosides using its transglycosylation activity pptx

Báo cáo khoa học: Kinetic studies on endo-b-galactosidase by a novel colorimetric assay and synthesis of N -acetyllactosamine-repeating oligosaccharide b-glycosides using its transglycosylation activity pptx
... in this work (A) Consecutive additions of GlcNAc and Gal to Galb1-4GlcNAcb-pNP by b3GnT and b4GalT (B) Consecutive additions of GlcNAc and Gal to Galb1-4Glcb-pNP by b3GnT and b-D-galactosidase ... of that of The same tendency was seen in a comparison of and This was also the case for B fragilis endo-b-galactosidase as shown in Table Transglycosylation reaction of endo-b-galactosidase from ... transglycosylation and time courses of the production of transglycosylation products and 10 from and degradation of (A) HPLC analysis was performed as described in Materials and methods (B) A reaction mixture...
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báo cáo hóa học: " The design and testing of a novel mechanomyogram-driven switch controlled by small eyebrow movements" docx

báo cáo hóa học:
... work was supported in part by an Ontario Graduate Scholarship, Natural Sciences and Engineering Research Council of Canada and the Canada Research Chairs program The authors acknowledge Mr Ka Lun ... the manuscript TC conceived the study, advised on the design and coordination of the experiments, and edited the manuscript All authors read and approved the final version of the manuscript Acknowledgements ... factor was selectable in the 1.2-2.5 range, and was adjusted for each participant such that false activations due to blinks and movement were avoided and participants were able to activate the switch...
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Báo cáo hóa học: " Facile Synthesis of Novel Nanostructured MnO2 Thin Films and Their Application in Supercapacitors" pptx

Báo cáo hóa học:
... surface of MnO2 and also possible intercalation/deintercalation of H? and alkaline metal cations in the bulk of MnO2 [29] Since the 3-D dandelion-like microspheres of the sample A are composed of ... 1036 substrate in the thin film form The effects of the synthesis temperature on the morphology of the films are investigated, and the capacitive behaviors of nanostructured MnO2 thin films with different ... scanning rate of 1°min-1 Surface morphology of the as-deposited thin films was characterized using a Hitachi S-4100 field emission scanning electron microscope (FESEM) Weights of the MnO2 thin films...
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synthesis and characterization of novel polymers for functional and stimuli responsive silicon surfaces

synthesis and characterization of novel polymers for functional and stimuli responsive silicon surfaces
... ProQuest Information and Learning Company 300 North Zeeb Road P.O Box 1346 Ann Arbor, MI 48106-1346 Synthesis and Characterization of Novel Polymers for Functional and Stimuli Responsive Silicon Surfaces ... Modification of Silicon/ SiO2 Surfaces with TTMS and Random Copolymers 241 241 241 242 Results and Discussion 7.4.1 Synthesis of TTMS 7.4.2 Synthesis of Poly(EHAM-co-AIEMA) 7.4.3 Silicon/ SiO2 ... describes the synthesis and characterization of novel amphiphilic block copolymers used as stimuli responsive coatings on surfaces The behavior of surfaces covalently modified with these copolymers...
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Design, optimization and applications of novel electrochemical sensors based on prussian blue

Design, optimization and applications of novel electrochemical sensors based on prussian blue
... logarithm of K+ concentration (inset of a) and logarithm of Na+ concentration (inset of b) S = electrode slope towards the logarithm of the relevant cation concentration Reproduced with permission from ... separation -based applications [30–32] As a continuation of the work on the Pt-coated nanoporous alumina membrane electrode, the direction of my honors year research project was on the exploration of ... a number of applications However, the pH stability of PB has been of concern, particularly under alkaline conditions [8] This constitutes a major drawback for PB -based applications, and much...
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Synthesis and characterization of novel jacketed polymers and investigation of their self assembly and application 6

Synthesis and characterization of novel jacketed polymers and investigation of their self assembly and application 6
... rigid core exert hindrance to self- assembly whereas the pyrimidine groups stabilized the self- assembly of jacketed polymers A series of novel jacketed liquid crystalline polymers, in which the terphenyl ... expected to help the self- assembly of the polymers The length of the alkyl chain and position of the alkyl chain on the mesogenic units appears to have significant effect on the self- assembly Besides ... between rigid segments and flexible segments, polar or nonpolar effect is investigated through the incorporation of the polar functional groups A series of novel jacketed polymers were synthesized...
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Synthesis and characterization of novel jacketed polymers and investigation of their self assembly and application 5

Synthesis and characterization of novel jacketed polymers and investigation of their self assembly and application 5
... of polymers 3a, 3b and 3c were measured in chloroform solution The absorption and emission spectra of the polymers are shown in Fig .5. 3 and the values as given in Table 5. 2 The UV spectrum of ... = 5. 2Hz, CCH(O)-, H), 4 .5 (d, J = 5. 5 Hz, O-CH2-, H), 2.7 (s, -OH, H) 13 CNMR ( 75. 4 MHz, CDCl3, δ ppm) 154 .2, 137.2, 134.7, 127.7, 126.7, 126.0, 1 25. 7, 1 25. 5, 121.0, 1 05. 3 (ArC), 69.4 (O-CH-), ... 300 400 50 0 wavelength (nm) Figure 5. 3 UV-vis absorption and Fluorescence spectra of polymers measured in chloroform at room temperature Table 5. 2 The detailed data of UV-vis absorption and Fluorescence...
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