... comparable to those of TvuCMBP The structures of TvuCMBP-G4 and unli˚ ganded EcoMBP are almost identical, with a 1.84 A rmsd (Fig 1D) The open and closed forms of several solute-binding proteins have ... open form Results and Discussion Overall structures of TvuCMBP–ligand complexes The crystal structures of TvuCMBP liganded with a-CD, b-CD and G4 have been determined at 1.7, 1.8 ˚ and 1.55 A resolutions, ... minor closed species in the absence of ligand [36], indicating 3016 that the conformation of the solute-binding protein could be determined by the ratio of the open fi closed rate to the closed fi open...