CIRCUMSTANCE AND CHOICE: THE ROLE OF INITIAL CONDITIONS AND POLICIES IN TRANSITION ECONOMIES

Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf

Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... raise the possibility that GSK3 may help to coordinate increases in glucose uptake and glycogen synthesis allowing for more effective ÔchannellingÕ of glucose into glycogen in response to insulin ... Effects of insulin, Li and SB-415286 on signalling elements implicated in the regulation of GSK3 and GS To further understand the effects of Li and SB-415286 on cell signalling events we assessed their ... by insulin Regulation of GS activity To establish the importance of GSK3 inhibition on GS activity we monitored the effects of insulin, Li, SB-415286 and wortmannin (a PI3K inhibitor) on the incorporation...
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Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... phenylalanine was therefore mutated to Ala, Leu, Trp or Tyr These mutations may in uence the shape and volume of the acyl binding pocket and thereby alter the binding mode and affinity of the enzyme ... PAA and derivatives thereof, while maintaining the hydrophobicity of the binding site To test the effect of the mutations on the specificity for phenylacetylated substrates, the steady-state kinetic ... the deacylation reaction in the active site of the acyl- enzyme have been changed by the bF24A mutation The rate-limiting step in the synthesis reaction is the acylation of the enzyme and it therefore...
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báo cáo khoa học: "The role of 18F-FDG-PET/CT in the preoperative staging and posttherapy follow up of gastriccancer:Comparison with spiral CT" docx

báo cáo khoa học:
... the decision of continuing the ongoing therapy or stopping and redirecting the patient to other salvage therapies Our study also supports the idea of routine use of PET or preferably PET/CT in ... and serial imaging tests The subjects were divided into three groups 4/42 of the analysed scans were performed for preoperative staging (group 1), 30/42 of the for posttherapy restaging (Group ... on spiral CT The superiority of PET/CT, a metabolic imaging tool, over CT in the preoperative N staging is marked in this case In the literature, although PET/CT does not have a role in T staging...
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Báo cáo y học: "Chronic whiplash and central sensitization; an evaluation of the role of a myofascial trigger points in pain modulation" docx

Báo cáo y học:
... (muscle pains) mayperpetuateandaccentuate thepain status of afflicted patients, [8,9] and Ge et al recently reported experimental evidence of a physiologic link between myofascial trigger points and ... study the authors set out to evaluate whether anesthetic infiltration of myofascial trigger points in patients with chronic and refractory neck pain can affect pain thresholds in uninjured parts ... tissues, and explained the finding as the expression of an abnormal processing of nociceptive information in the brain and spinal cord [2-7] Others have postulated that chronicposttraumatic myalgia...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production

The Role of Genetically Modified Organisms (GMOs) in Beverage Production
... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes in ... Finally, the food and beverage industries hope that the next generation of GM products will deliver compelling consumer beneÞts THE FUTURE OF GENETICALLY MODIFIED FOODS The next generation of ... of relevance to the beverage industry will be provided HISTORY OF GENETIC MODIFICATION OF FOOD PLANTS AND ANIMALS People have been genetically modifying the food supply during the thousands of...
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Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx

Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx
... helix of the third cluster of CHCs is part of the inter-domain segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation of the ... rather than functional role Role of hydrophobic contacts in serine hydroxymethyltransferase In the present study, the importance of the third hydrophobic cluster as a structural determinant of ... Y55¢ interacts with the phosphate moiety of PLP; E57¢ is crucial in the binding of the l -serine hydroxyl group [15] and in the catalysis of the hydroxymethyltransferase reaction [16]; and Y65¢ interacts...
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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx
... of glycogen in the intact liver in vivo Second, during infusion of [1-1 3C ]glucose, label incorporation was observed not only into the C1 of glycogen but also the C6 , which can only occur by label ... a mechanism can lead to increases in labeling of glycogen C6 even in the presence of decreased activity of the indirect pathway, provided that the increase in glycolytic flux exceeded the decreased ... (A) The stack plot of 1 3C spectra acquired over 7.6 h after beginning at t ¼ (right scale), the infusion of [1-1 3C ]glucose 1 3C- label incorporation into hepatic glycogen was detected in the glycogen...
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The role of floating-rate bank loans in institutional portfolios pdf

The role of floating-rate bank loans in institutional portfolios pdf
... not indicative of future results Russell Investments // Role of bank loans in a rising rate environment / p6 Bank loans in rising interest rate environments In the past 20 years (since 1992), there ... of St Louis, U.S Department of the Treasury Indexes are unmanaged and cannot be invested in directly Past performance is not indicative of future results Russell Investments // Role of bank loans ... used index “ designed to mirror the investable universe of the U.S dollar denominated leveraged loan market.” https://www.credit-suisse.com Russell Investments // Role of bank loans in a rising...
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Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx

Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx
... monophosphate kinases L Wang supply of nucleoside monophosphates may regulate the synthesis of nucleoside di- and triphosphates In Mollicutes, other enzymes exist that are capable of synthesizing nucleoside ... purification of Ureaplasma nucleoside monophosphate kinases Primers used in PCR amplification of Ureaplasma nucleoside monophosphate kinases were designed according to the DNA sequence of the respective ... volume of 20 lL The reaction was initiated by the addition the enzyme (100 ngÆreaction)1 for the determination of NTP synthesis rates and 0.5–1 ngÆreaction)1 for the determination of NDP synthesis...
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báo cáo hóa học: " The role of cumulative physical work load in symptomatic knee osteoarthritis – a case-control study in Germany" potx

báo cáo hóa học:
... http://www.occup-med.com/content/3/1/14 Table 2: Occupational exposure to kneeling/squatting and lifting/carrying of loads and symptomatic knee osteoarthritis Variable Cases N % Kneeling and squatting combined No kneeling/squatting ... kneeling work D'Souza et al [20] examine the relationship between the daily amount of kneeling and knee osteoarthritis in the subset of participants at the Third National Health and Nutrition Examination ... combination of kneeling and heavy lifting According to our study the knee osteoarthritis risk is particularly elevated in occupations that involve both kneeling/squatting and heavy lifting/carrying...
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Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps

Báo cáo y học:
... anti-IL-1 therapy AntiIL-17 cytokine therapy might be an interesting new antirheumatic approach that could contribute to the prevention of joint destruction as an adjunct to anti-TNF and anti-IL-1 therapy ... together regulate interleukin-17- induced nitric oxide production in human osteoarthritic chondrocytes: possible role of transactivating factor mitogen-activated protein kinase-activated protein ... (IL-17) in relation to other key cytokines in the pathogenesis of arthritis RANKL, receptor activator of NF-κB ligand; TNF, tumor necrosis factor inactivation of IL-17 [40] In line with the situation...
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Báo cáo y học: "The role of tumor necrosis factor-alpha in systemic lupus erythematosus" pdf

Báo cáo y học:
... interfere with the inflammatory response in SLE by administering only an induction regime of four infusions of infliximab within 10 weeks rather than by planning for long-term therapy Evidence for ... vascular permeability J Clin Invest 2002, 110:433-435 67 Aringer M, Graninger WB, Steiner G, Smolen JS: Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an ... TNF often is a survival signal (green lines) and plays a role in maintaining survival niches for long-lived plasma cells (PlasmaC) Some of these effects are indirect in part, involving cytokines...
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báo cáo khoa học: " Multiple evidence for the role of an Ovate-like gene in determining fruit shape in pepper" pptx

báo cáo khoa học:
... between the CaGA20ox1 expression in the two fruits: there is an increase in the expression of the gene in the DAA fruit of the infiltrated plant compared to the expression in the DAA fruit of the ... fruits of the infiltrated plant exhibit an average fruit shape index more than 1, characteristic of their oblong shape, while the average fruit shape index of the fruits of the WT is lower than The ... reference gene that of the wild type Specifically, the average fruit shape index is 1.14 for the fruits of the infiltrated plant while the average fruit shape index of the fruits of the WT is...
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Báo cáo khoa học: "The role of high-frequency oscillatory ventilation in paediatric intensive care" pot

Báo cáo khoa học:
... where it is possible to maintain relatively high end-expiratory lung volumes without inducing overdistension Many of the available data regarding the use of HFOV in the paediatric population are ... supporting the use of HFOV in the treatment of severe respiratory failure in children, studies in the paediatric population have not been able to demonstrate any significant improvements in clinically ... FB: High Frequency Oscillatory Ventilation in Children: a single center experience of 53 cases Crit Care 2005, 9:R274-R279 Froese AB, Kinsella JP: High-frequency oscillatory ventilation: Lessons...
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