... chronic schizophrenia: Assessment with xenon 133 single-photon emission computed tomography and the Tower of london Arch Gen Psychiatry, 1992; 49:943-958 Kwon JS, McCarley RW, Hirayasu Y, Anderson ... that the efficacy of Clozapine is clinically significant on the negative symptomatology but is delayed compared to the efficacy on the other dimensions of symptomatology evaluated using the PANSS ... J Psychiatry 1993; 150:1325-1336 Gordon E, Barry RJ, Anderson J, Fawdry R, Yong C, Grunewald S, Meares RA Single photon emission computed tomography (SPECT) measures of brain function in schizophrenia...