... (University of California, Los Angeles, USA) first reviewed the principles of amyloid fibril formation and then discussed his work studying the structures of amyloid fibrils using X-ray crystallography ... microscopy, and something about mass spectrometry, but today nearly every structural problem has been studied using at least three techniques, or more.” This captured one of the themes of the meeting, ... unique challenges related to the fact that these proteins are normally much larger than structures typically solved by NMR, and the usual scarcity of constraints at the interdomain interface, which...