... SRPK1 and SRSF1, together with crystal structures of SRPK1 bound to peptide and protein substrates and the recent structures of CLK1 and CLK3, suggest an elegant mechanism of recognition and phosphorylation ... sequential and processive phosphorylation of an SR protein by SRPK1 Mol Cell 29, 563–576 29 Ma CT, Ghosh G, Fu XD & Adams JA (2010) Mechanism of dephosphorylation of the SR protein ASF ⁄ SF2 by protein ... nuclear distribution of SRSF1 and other SR proteins Thus, through interactions with two families of protein kinases, the cellular location and, presumably, splicing function of SR proteins can be...