... B Double KO C elegans metallothioneins are not the only players in metal detoxification and homeostasis The effects on the ligand environments of cadmium and zinc upon deletion of metallothioneins ... in C elegans In contrast, the reduced accumulation, or excretion, of cadmium and zinc is MT-mediated, as there was a large effect on the levels of accumulated zinc and cadmium when CeMT-1 and ... deal with cadmium and zinc We have shown for the first time that the responses to cadmium and zinc ions at the cellular level are isoform-specific, and that this specificity is reflected at the protein...